Team Building the Pipeline of IDeAs: Strength in the diversity of our students, faculty, and community

Day 1 - July 26th

8:30-9:20 Opening Remarks and Introduction
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  8:30-8:40 Paul Sorgen, Ph.D.  NE-INBRE PI
  Moderator: Steve Caplan (UNMC, NE-INBRE PC-Research Institutes)
  8:40- 9:10 (Presentation) Jon R. Lorsch, Ph.D. NIGMS Director
  9:10-9:20 (Q&A) Jon R. Lorsch, Ph.D. NIGMS Director
9:20-9:50 Keynote Speaker
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  Moderator: Surinder Batra (UNMC, Chair Biochemistry and Molecular Biology)

Ali Khan MD, MPH, MBA (Dean, College of Public Health, UNMC)
Title: Science and anti-science in the age of COVID

9:50-10:20 IDeA Leaders (10 min each)
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  Moderator: Paul Sorgen (UNMC, PI NE-INBRE)
  9:50-10:00  Konstantin Gus Kousoulas, Ph.D.  NAIPI President
  10:00 - 10:10 Doug Wright, Ph.D.   SHARP HUB
  10:10 - 10:20 Matthew Rizzo, M.D.  Great Plains IDeA-CTR
10:20-10:30 Break
10:30-11:00 Workshop: Team Building the Pipeline of IDeAs (Matt Rizzo, M.D., Babu Guda, Ph.D., and Paul Estabrooks, Ph.D.)
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11:00-12:30 Concurrent Session (6x 10 min talks with 5 min Q/A)
  A. Cancer Biology (Co-Chairs: Drs. Ma (OUHSC) and Zempleni (UNL))
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11:00 Sandeep K Singhal University of North Dakota
  Title: Racial disparity and molecular biology of breast cancer: A multi-omics approach
11:15 Joshua Corbin Oklahoma University Health Sciences Center
  Title: AN-DISE: A potential RNA interference-based therapy for prostate cancer
11:30 Fangfang Qiao University of Nebraska Medical Center
  Title: Ctdp1 deficiency results in early embryonic lethality and lactation defects in mice
11:45 Horrick Sharma Southwestern Oklahoma State University
  Title: Discovery of a Novel Class of LDH inhibitors against Cancer
12:00 Dianna Huisman University of Nebraska Medical Center
  Title: Molecular Characterization of Tumor Initiation in Small-cell Lung Carcinoma
12:15 Derek Baldwin Wichita State University
  Title: Observing actin structures and organization to reveal Palladin’s role in metastasis
  B. Viruses and Bacteria (Co-Chairs: Drs. Huber (USD) and Liu (OSU)) 
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11:00 Sydney Newsom University of Oklahoma Health Sciences Center
  Title: Ranking potential drug targets in coronavirus spike protein by analyzing amino acid functional conservation and evolutionary pressure
11:15 Miruthula T. Selvan Oklahoma State University
  Title: Establishing a naturally occurring Feline model for SARS CoV-2 infection and disease
11:30 Phoebe Pena University of Nebraska Lincoln
  Title: Impact of pre-existing serological cross-reactivity against SARS-CoV-2 on cancer patients in sub-Saharan Africa
11:45 Lauren Zenewicz University of Oklahoma
  Title: A Clostridioides difficile toxin induces activation of innate lymphocytes
12:00 Austin Nuxoll University of Nebraska Kearney
  Title: Decreased Tricarboxylic acid (TCA) cycle in Staphylococcus aureus increases survival to innate immunity
12:15 Chyeyenne Loo University of Kansas
  Title: Promiscuity of the Chromobacterium subtsugae QS receptor CviR and its role in interspecies competition
12:30-1:00 Lunch Break
1:00-2:15 Poster Session 1 (Faculty/Graduate Students/Undergraduate Students)
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2:15-3:45 Concurrent Session (6x 10 min talks with 5 min Q/A)
  A. CTR (Co-Chairs: Drs. Basson (UND) and VanWagoner (OUHSC))
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2:15 Michael G. Nichols Creighton University
  Title: In vivo quantification of metabolic and tissue architectural changes associated with UVA-induced skin cancer in SKH1 Mice
2:30 Kathryn Burge University of Oklahoma Health Sciences Center
  Title: Hyaluronic acid 35 kDa protects against necrotizing enterocolitis in a hyperosmotic, formula feeding mouse model
2:45 James Fletcher Creighton University
  Title: Synthesis and antimicrobial evaluation of 1,2,3-triazole-containing phenanthridines
3:00 Mark K. Larson Augustana University
  Title: Differential Platelet Responses in Native Americans
3:15 George Varghese Creighton University
  Title: Early detection of Squamous Cell Carcinoma by NADH Phasor FLIM in SKH1 Mice
3:30 Shane Scholten Augustana University
  Title: Ischemic preconditioning effects on physical performance.
  B. Neuroscience (Co-Chairs: Drs. Kirkpatrick (KSU) and Dunavesky (UNMC))
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2:15 Lara Bergdolt University of Nebraska Medical Center
  Title: Astrocytic contribution to audiogenic seizure susceptibility in a mouse model of fragile X syndrome
2:30 Jennifer Sexton University of Nebraska Medical Center
  Title: Investigating the association between Hippocampal volume and neuropsychological abilities vulnerable to Alzheimer's Disease: A developmental approach
2:45 Danielle Germundson University of North Dakota
  Title: Repeated allergen exposure triggers neuroinflammation and behavioral changes in a mouse model of asymptomatic cow’s milk allergy
3:00 Carly Baker Creighton University
  Title: Characterization of CPTII Knockdown on Zebrafish Body and Brain Development and Function
3:15 Anastasia Kerr-German Boys Town National Research Hospital
  Title: Moving Towards a viable characterization of the neurocognitive mechanisms underlying the development of ADHD
3:30 DeSilva Mohotti University of Kansas
  Title: Defining lipid changes during demyelination & myelin repair using a novel genetic mouse model
3:45-3:55 Break
3:55-4:25 Keynote Speaker
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  Moderator: Doug Wright (KUMC, PI KU-INBRE and SHARP HUB)

Steve Soper Ph.D. (Department of Chemistry, KU)
Title: Convergence of medicine and engineering: Building unique research and educational infrastructure focused on precision medicine


Day 2 - July 27th


8:30-8:35 Opening Remarks
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8:35-9:05 Concurrent Sessions
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  1. Undergraduate Workshop (Dr. Sorgen, UNMC)
  2. Graduate Student Workshop (Dr. Caplan, UNMC)
  3. Faculty Workshop - High Risk High Reward (HRHR) Program (Dr. Basavappa, Program Leader for the Common Fund program in the NIH Office of Director)
  4. Core Facilities Workshop (Kuenstling, Ph.D., Michael Kinter, Ph.D., Cyndi Anderson, Ph.D., and Chamani Perera, Ph.D.)
9:05-9:35 Keynote Speaker
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  Moderator: Kate Hyde (UNMC, NE-INBRE Cancer Biology Scientific Theme Director)
  Sheritta Strong M.D. (Director of Inclusion, UNMC)
Title: Can having a growth mindset improve DEI in research?
9:35-9:45 Break
9:45-11:15 Concurrent Session (6x 10 min talks with 5 min Q/A)
  A. Drug Addiction and Targets (Co-Chairs: Drs. Paulus (UO) and Bevins (UNL))
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9:45 Manali Kamath University of Oklahoma Health Sciences Center
  Title: The unfolded protein response is essential for the corneal pathogenesis of Aspergillus fumigatus
10:00 Nathan Zimmerman Creighton University
  Title: Effects of Psychopharmaceuticals on neuronal sterol synthesis
10:15 Sarah Alsuleiman University of Nebraska at Omaha
  Title:  Bone marrow transcriptomics suggest immunomodulation of promising anti-Schistosoma analog SA01
10:30 Julie Soukup Creighton University
  Title:  Evolutionary conservation of ornithine decarboxylase antizyme pseudoknot RNA binding to spermine
10:45 Jetty Duffy-Matzner Augustana University
  Title: Chitosan, hyaluronic acid biopolymer (LbL) assembly on siloxy amino functionalized balafilcon A contact lenses
11:00 Caleb Sandall  University of Nebraska at Omaha
  Title: Changes in Reactive Species Production Caused by the Novel Anti-Schistosomal Compound CS01
  B. Molecular Target Discovery and Development/Nanomedicine (Co-Chairs: Drs. West (OU) and Guzman (KU))
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9:45  Suman Maharjan Oklahoma State University 
  Title: Cell shape variation in Escherichia coli with point mutations in mreB
10:00  Isioma Akwanamnye Chadron State College
  Title: The title of my presentation is the Effect of Curcumin on gene expression induced by the NF-KB pathway in Triple-Negative breast cancer
10:15 Sadegh Nikfarjam University Central Oklahoma
  Title: Laser microgrooving and nanofiber membrane application for total knee replacement  implants using a Caprine model
10:30  Evelyn Carreto University of Nebraska Medical Center
  Title: Investigation of Molecular Adducts Formed with a Novel NTSR1-targetted Radiotherapeutic in the Pancreatic Cancer Cell Line
10:45  Vivek Swmi University Central Oklahoma
  Title: The title of my project is effect of PCL nanofiber support of an in vitro skin equivalent
11:00  Emily Gilbert  College of St. Mary
  Title: The formulation, development, and analytical characterization of polyphenolic combinations
11:15-12:30 Poster Session 2 (DRPP Faculty/Graduate Students/Undergraduate Students)
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12:30-1:45 INBRE Undergraduate Rising Stars (Julie Soukup, CU, NE-INBRE PC-Primary Undergraduate Institutes)
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12:30 Johnny Dinh Phan University of Kansas Medical Center (KU)
  Title: TBA
12:45 Elizabeth Holmes* & Jason Becker* Augustana University (SD)
  Title: Antimicrobial effects of placenta on Staphylococcus aureus biofilms
*Both authors contributed equally; both will be presenting
1:00 LeeAnna Lui University of Nebraska Omaha (NE)
  Title: Developing a combinational drug therapy against the chronic stage of Toxoplasma gondii
1:15 Nicholas Bergum University of North Dakota (ND)
  Title: Chronic Exposure to Arsenic Increases the Invasiveness of the Luminal Bladder Cancer Cell Line, RT4
1:30 Emily Bedea Southwestern Oklahoma State University (OK)
  Title: Identification and Characterization of an Important Metabolic Enzyme from Streptococcus Sanguinis
1:45 Conference Remarks - Paul Sorgen (UNMC, PI NE-INBRE)
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              2022    NISBRE(Washington D.C.)
              2023    Central Region IDeA Meeting(Kansas)