University of Nebraska Medical Center

Mark Rupp, MD

Chief, Division of Infectious Diseases
Professor, Department of Internal Medicine
Medical Director, Infection Control & Epidemiology
Associate Medical Director, Antimicrobial Stewardship 


Mark Rupp

Dr. Rupp is a professor and Chief of the Division of Infectious Diseases in the Department of Internal Medicine at the University of Nebraska Medical Center. He is the Medical Director of the Nebraska Medical Center Department of Infection Control & Epidemiology.

Dr. Rupp received his medical degree from Baylor College of Medicine, Houston, Texas, and holds a bachelor's degree in chemical engineering from the University of Texas at Austin. He underwent internship and residency training in Internal Medicine and completed Fellowship training in Infectious Diseases at Virginia Commonwealth University. He is board certified in infectious diseases.

He is a Diplomate, American Board of Internal Medicine in the subspecialty area of Infectious Diseases. He is a Fellow of the American College of Physicians, the Infectious Diseases Society of America, and the Society for Hospital Epidemiology of America (SHEA). He is a past president of SHEA (2009). Dr. Rupp has served as a consultant for the U.S. Food and Drug Administration, the Centers for Disease Control and Prevention, the National Institutes of Health, and the VA. He recently served as the Chief of Staff at Nebraska Medicine.

Dr. Rupp has published nearly 500 peer-reviewed articles, chapters, and abstracts and holds three U.S. patents. His research efforts have been funded by the NIH, CDC, VA, AHA, and industry. He frequently presents papers at national and international meetings, serves as a guest lecturer, and is an active teacher and researcher. Dr. Rupp’s research interests are in the areas of health care-associated infections and antimicrobial stewardship.


  • Medical School: Baylor College of Medicine, 1984
  • Fellowship: Microbiology, Baylor College of Medicine, 1985
  • Internship: Medical College of Virginia, 1986
  • Residency: Internal Medicine, Medical College of Virginia, 1988
  • Fellowship: Infectious Disease, Medical College of Virginia, 1991