What is Central IRB?

The UNMC IRB uses the term “central IRB” or “cIRB” to indicate that the reviewing IRB (i.e., the IRB of record) of a multisite study is external to UNMC.

The UNMC IRB has contracted with two commercial IRBs, Advarra and WCG. In addition, the UNMC IRB partners with consortium, academic, and medical center IRBs nationwide.

For more details around the use of a cIRB, including when the use of an external central IRB is not permitted, see UNMC HRPP Policy 1.4., UNMC Ceding Review to an External Central IRB.