Tissue Sciences Facility
The UNMC Tissue Sciences Facility (TSF) provides comprehensive histology, immunohistochemistry, imaging, and pathology support services for animal and human tissue research. The facility offers standardized and specialized services including tissue processing, embedding, sectioning, paraffin and frozen staining, multiplex immunohistochemistry/immunofluorescence, digital slide scanning, tissue microarray construction, and technical support for client-use instrumentation.
TSF supports investigators through expert technical guidance, pathology consultation, and training on specialized histology procedures and equipment. Services are available to University of Nebraska researchers, external academic institutions, and industry partners.
Led by Medical Director Dinesh Pradhan, MD, TSF provides expert guidance in specialized sample preparation, histology, imaging, staining, immunohistochemistry, and frozen sectioning. Skilled technologists are also available to assist researchers throughout the tissue processing and imaging workflow.
Submission Services
For more information regarding Tissue Sciences Facility policies, please see core personnel.
Please contact the lab when planning a project to discuss sample handling, tissue fixation and embedding to avoid any delays.
A standard turn-around time of five or 10 business days is assigned to orders at the time of submission; turn-around times are dependent on the complexity and size. Antibody optimization, tissue micro array construction, image analysis services or client dependent projects are not subject to assigned turn-around times. Orders are accepted 9 a.m. to 3:45 p.m. Monday through Friday on a first-come, first-served basis. Samples received after 3:45 p.m. will not be processed until the following business day.
- Fixed specimens, unless otherwise noted, are assumed to be at their end fixing point.
- Tissue should be no more than 2-3mm thick in 20 times the fixative volume.
- Fresh Formalin works best.
- 70% Ethanol is the preferred drop-off solution, but 10% NBF or other fixatives are accepted in containers properly labeled with all hazards and cautions.
- Any hazardous samples, biohazard, radiation, etc., must be pre-approved before drop-off.
- Please contact core personnel for any special embedding or tissue orientation request.
- Please supply all samples in individual cassettes with proper labeling that matches paperwork; a typed specimen ID list is required.
- Use pencil or solvent-resistant marking pen (Surgipath01880).
- Use of a simple coding system containing no more than 8 characters is recommended.
- Patient names are never accepted.
Orders are accepted anytime in DRC1 1059, in our self-service room; orders received after 3:45 p.m. may be processed the following business day. Samples must be accompanied with a completed order form. A cost center is required at the time of submission, and any order without a cost center will not be processed. Specimen submission containers are available free of charge and can be picked up anytime in DRC1 1059, in our self-service room.
User will be notified via email or phone when orders are ready for pickup.
Boxes for slides are available for purchase.
Orders may be picked up anytime in DRC1 1059, in our self-service room.
Tissue Sciences Facility
University of Nebraska Medical Center
601 South Saddle Creek Rd
DRC1 1052
Omaha, NE 68106-5815
TSF Price List
Prices are subject to change and are for University of Nebraska institutions only as of July 1, 2025. Click here for the TSF price list.
For external researchers or clinical trials pricing, please contact Ember Eldridge, TSF Supervisor.
How to Cite Our Core Facility
Publications resulting from work performed in the Tissue Science Facility should include the core's Research Identifier (RRID).
“We recognize the use of the University of Nebraska Medical Center - Tissue Science Facility, RRID:SCR_012465, which receives support from the Buffett Cancer Center Support Grant P30CA03672.”
TSF Contact Info
Hours: 10:00 AM - 3:00 PM Facility Location: DRC1 1052 Lab Phone: 402-559-5123 Email: tissuescifacility@unmc.edu