University of Nebraska Medical Center

Huangui Xiong, MD, PhD

  • PhD in Neurophysiology, University of Ottawa, Canada, 1993
  • MD in Surgery, Southern Medical University, Guangzhou, China, 1981
  • Distinguished Scientist, UNMC 2010
Selected Publications
  • Dutta D, Liu J, Xiong H.  The Impact of COVID-19 on People Living with HIV-1 and HIV- 1-Associated Neurological Complications. Viruses 15(5): 1117, 2023
  • Zheng Y, Reiner B, Liu J, Xu L, Xiong H.  Methamphetamine augments HIV-1 gp120 inhibition of synaptic transmission and plasticity in rat hippocampal slices: Implications for methamphetamine exacerbation of HIV-associated neurocognitive disorders. Neurobiol Dis 168:105712, 2022
  • Zhang J, Gong X, Xiong H.   Significant higher-level C-C motif chemokine ligand 2/3 and chemotactic power in cerebral white matter than grey matter in rat and human. Eur J Neurosci  Mar 16;10.1111/ejn.15187. doi: 10.1111/ejn.15187, 2021
  • Xu E, Liu J, Liu H, Wang XB, Xiong H. Inflammasome activation by methamphetamine potentiates lipopolysaccharide stimulation of IL-1β production in microglia. J Neuroimmune Pharmacol.  13(2):237-253. 2018
  • Liu J, Xu E, Tu G, Liu H, Luo J, Xiong H. Methamphetamine potentiates HIV-1gp120 induced microglial neurotoxic activity by enhancing microglial outward K+ current. Mol Cell Neurosci. 82:167-175, 2017
  • Zhou Y, Liu J, Xiong H. HIV-1 Glycoprotein 120 Enhancement of N-Methyl-D-Aspartate NMDA Receptor-Mediated Excitatory Postsynaptic Currents: Implications for HIV-1-Associated Neural Injury. J Neuroimmune Pharmacol. 12(2):314-326, 2017
  • Liu H, Liu J, Xu E, Tu G, Guo M, Liang S, Xiong H.  Human immunodeficiency virus protein Tat induces oligodendrocyte injury by enhancing outward K+ current conducted by KV1.3.  Neurobiol Dis. 97(Pt A):1-10, 2017
  • Yang JM, Hu D, Liu J, Boukli NM, Xiong H.  Enhancement of NMDA receptor-mediated excitatory postsynaptic currents by gp120-treated macrophages: Implications for HIV-1-associated neuropathology.  J. NeuroImmune Pharmacol.  8:921-933, 2013
  • Hu D, Liu J, Keblesh JP, Xiong H. Involvement of the 4-aminopyridine sensitive transient A-type K+ current in macrophage-induced neuronal injury. Eur J Neurosci. 31:214-22, 2010
  • Anderson, E.R., Gendelman, H.E. Xiong, H.   Memantine Protects Hippocampal Neuronal Function in a Murine Model of HIV-1 Encephalitis.  J Neurosci 24:7194-7198, 2004.