University of Nebraska Medical Center

Subhash Chand, PhD

Instructor, UNMC Department of Anesthesiology
Research Faculty

Subhash Chand, PhD
Research Interests
  • HIV infection, substance abuse, and related cardiovascular comorbidities.
  • Impact of inflammation and extracellular vesicles (EVs) in HIV infection-associated comorbidities.
  • Modulation in endocannabinoid system in HIV infection and substance use disorders.
  • Chand S, DeMarino C, Gowen A, Cowen M, Al-Sharif S, Kashanchi F, Yelamanchili SV, "Methamphetamine Induces the Release of Proadhesive Extracellular Vesicles and Promotes Syncytia Formation: A Potential Role in HIV-1 Neuropathogenesis" (Viruses, 2022) Impact Factor = 5.818PMID: 35336957 PMCID: PMC8950763 DOI: 10.3390/v14030550.
  • Chand S, Gowen A, Savine M, Moore D, Clark A, Huynh W, Wu N, Odegaard K, Weyrich L, Bevins RA, Fox HS, Pendyala G, Yelamanchili SV, "A comprehensive study to delineate the role of an extracellular vesicle-associated microRNA-29a in chronic methamphetamine use disorder Journal of Extracellular Vesicles" (Journal of Extracellular Vesicles, 2021) Impact Factor = 17.337. PMID: 34913274 PMCID: PMC8674191 DOI: 10.1002/jev2.12177.
  • Jain S, Uritskiy, Mahalingam M, Batra H, Chand S, Trinh H, Beck, Shin W, AlSalmi W, Kijak, Eller LA, Kim J, Kihara D, Tovanabutra S, Ferrari G, Robb M, Rao M, Rao VB, "A genetic shift in an escaped transmitted/founder virus guides combinatorial vaccine design against HIV-1" (bioRxiv, 2021)DOI: 10.1101/2021.06.16.448593.

Bridge Funding Award ($75,500) 01/01/2023 - 12/31/2023

“MicroRNAs in Heart Derived Extracellular Vesicle as Diagnostic Biomarkers of Heart Failure in People Living With HIV”

Lieberman Research Award ($25,000) 05/03/2022 - 12/31/2023

“Impact of HIV and polysubstance use disorder on the cardiovascular function”

Nebraska Center for Nanomedicine Core ($5,000)  08/01/2022 - 09/30/2023

“This proposal aims to delineate the role of extracellular vesicles (EVs) in dilated cardiomyopathy under HIV-1 and methamphetamine comorbidity.”