Glaucoma pharmacology and physiology
Dr. Shan Fan is interested in clinical and animal studies on effects of glaucomatous disease process on fluid flow within the eye. Glaucoma has long been recognized as a leading cause of blindness in the United States and worldwide. Abnormalities in aqueous humor may elevate intraocular pressure (IOP) and high IOP is a major risk factor for the development of glaucoma. She and her collaborators are focusing on the aqueous humor dynamics studies and how different medications and drainage devices can be utilized to treat glaucoma.
Ethnicity plays an important role in glaucoma prevalence of different types. Previous surveys and studies have suggested that primary open-angle glaucoma is more common in people of European or African descent but primary angle-closure glaucoma is more prevalent in Asians. She is interested in studying whether there are some significant differences in aqueous humor dynamics exist between Caucasian and Asian populations and it may lead to improved screening and treatment options for glaucoma in both populations.
Lanzhou Medical School, Lanzhou, Gansu, P.R. China
Fellowship: The Eye Hospital of Tianjin, P.R. China
Visiting Physician: Mayo Clinic and Mayo Foundation, Rochester, MN