Research Faculty Bio

Dahn Clemens, PhDDahn Clems, Ph.D.
Associate Professor, Internal Medicine
Division of Cardiovascular Medicine

Academic office:
3005 Wittson Hall
Department of Internal Medicine
982265 Nebraska Medical Center
Omaha, NE 68198-2265
dclemens@unmc.edu


Education:

Ph.D., Microbiology, Colorado State University, Fort Collins, CO, 1984 - 1989

M.S., Microbiology, Idaho State University, Pocatello, ID, 1981 - 1984

B.A., Biology, Saint Mary’s College, Winona, MN, 1975 - 1979

Biographical Sketch:

1989 - 1992 IRTA Fellow, Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratory, NIAID, NIH , Hamilton, MT

1992 - 2004 Assistant Professor, Department of Internal Medicine, University of Nebraska Medical Center and VA Medical Center, Omaha, NE, Assistant Professor, Department of Pathology and Microbiology, University of Nebraska Medical Center and VA Medical Center, Omaha, NE

1992-2016 Research Biologist and Chief of Molecular Biology, Omaha VA Medical Center , Alcohol Center, Omaha, NE

2004- present Associate Professor, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, Associate Professor, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE

2013-present Member, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE 

Research Expertise:

Doctor Clemens has a long-standing interest in the role of inflammation in the pathogenesis of disease. He has recently joined the Division of Cardiology, where his research will focus on the role of inflammation in cardiovascular disease. Specifically, he is interested in determining the molecular mechanisms by which reactive oxygen species cause inflammation and how these mechanisms lead to the initiation and progression of cardiovascular disease. Additionally, Dr. Clemens is interested in determining the effectiveness of antioxidants and anti-inflammatory agents in preventing and treating cardiovascular disease.

Publications:

Ding WX, Chen X, Ni HM, Gao W, Lu B, Stolz DB, Clemens DL, and Yin XM. Mitigation of Ethanol-induced Hepatotoxicity and Steatosis by Autophagy.  Gastroenterology 139: 1740-7152, 2010 PMID: 20659474

Clemens DL, Mahan KJ, Nuss RF, Ethanol Metabolism Activates DNA Replication Check Points. Alcohol. 45: 785-793, 2011 PMID: 21924579

Petrosyan A, Pi-Wan Cheng PW, Dahn L. Clemens DL, and Casey CA. Downregulation of the Small GTPase SAR1A: A Key Event Underlying Alcohol-Induced Golgi Fragmentation in Hepatocytes. Scientific Reports. 5:17127, 2015 PMID: 26607390

Cho NE, Gurung P, Li M, Clemens DL, Underhill TM, James LP, Chase JR and Saito T. Retinoid Regulation of Antiviral Innate Immunity in Hepatocytes. Hepatology: 63:1783-95, 2016  PMID: 26638120

Clemens DL, Schneider KJ, Arkfeld CK, Grode JR, Wells MA, and Singh S. Alcoholic Pancreatitis: New Insights Into the Pathogenesis and Treatment. World J Gastrointest Pathophysiol. 7(1):48-58, 2016 PMID: 26909228

Marc A. Scheer, Katrina J. Schneider, Rochelle L. Finnigan, Eamon P. Maloney, Mark A. Wells, and Dahn L. Clemens. The Involvement of Acetaldehyde in Ethanol-Induced Cell Cycle Impairment. Biomolecules. 6. pil: E17, 2016 PMID: 27043646

Sarawathi    Saraswathi, Curtis Perriotte-Olson, Murali Ganesan, Cyrus V. Desouza, Yazen Alnouti, Michael J. Duryee, Geoffery M. Thiele, Tara M. Nordgren, Clemens DL. A combination of dietary N-3 fatty acids and a cyclooxygenase-1 inhibitor attenuates nonalcoholic fatty liver disease in mice. J Nutr Biochem. 42:149-159, 2017 PMID: 28187366

For more publications