Daniel R. Anderson, M.D., Ph.D.
Acting Chief of Cardiovascular Medicine
Associate Professor
Dyad Leader with Dr. Moulton
Division of Cardiovascular Medicine

Academic office:
Department of Internal Medicine
982265 Nebraska Medical Center
Omaha, NE 68198-2265

Practice Locations:
Omaha, Nebraska
Durham Outpatient Center
For An Appointment Call (402)559-8888
Toll Free 1-800-97-HEART (1-800-974-3278)

Oakview Medical Building
For An Appointment Call (402)559-8888
Toll Free 1-800-97-HEART (1-800-974-3278)

Hospital Appointments:
Nebraska Medicine
 
Board Certification:
Cardiovascular Medicine
Clinical Cardiac Electrophysiology 

Education:
University of Nebraska Medical Center (Omaha, NE)
Doctorate of Philosophy, 1996
Doctor of Medicine, 1998
Resident - Internal Medicine, 2002
Fellow - Cardiovascular Disease, 2005
Fellow - Electrophysiology, 2006

Clinical Interests:  

Cardiac electrophysiology: Cardiac Electrophysiology is the science of the mechanisms, functions, and performance of the electrical activities of specific regions of the heart. Dr. Anderson’s specific clinical interests include understanding the aspects and contributing factors involved in atrial and ventricular arrhythmias, as well as in atherosclerosis and ischemic cardiomyopathy. Such arrhythmias are conditions in which the electrical activity of the heart is irregular, is faster or slower than normal and can be life threatening. 

Research Interests:

Molecular and cellular immunology is the foundation of Dr. Anderson’s research. Dr. Anderson has a specific focus and interest in innate immunity (preexisting immunity) and how such immune responses contribute to the mechanisms of cardiovascular disease processes. His studies have specifically focused on underlying mechanisms of viral myocarditis, atherosclerotic disease and the impact inflammation has on cardiac rhythm abnormalities. Recent studies have detailed the role of inflammation in arrhythmogenesis and atherosclerosis. Dr. Anderson has also detailed the utility of microbubble technology in the detection and monitoring of vascular inflammation. 

Ongoing Research Support:

Grant Title: Protein Adduction and Cardiovascular Disease
Funding Agency: Harry R & Sarah H Caspersen Coronary Artery Disease Research Foundation
Start and end dates: September 2015 - September 2017
Role: Principal Investigator

Grant Title: Cardiovascular Inflammation Reduction Trial (CIRT)
Funding Agency: NIH
Start and end dates: February 2014 - February 2019
Role: Site Principal Investigator

St. Jude Medical: September 2007 - Present
OPTIMUM Lead Insulation Material Registry
Role: Study Site Principal Investigator

Start-up Funds

Detection and Monitoring of Vascular Inflammatory Events

Role: Principal Investigator 

NIH Loan Repayment Award:  July, 2007- June, 2009

Publications

1. Anderson DR, Duryee MJ, Shurmur SW, Um JY, Bussey WD, Hunter CD, Garvin RP, Sayles HR, Mikuls TR, Klassen LW, Thiele GM. Unique Antibody Responses to Malondialdehyde-Acetaldehyde (MAA)-Protein Adducts Predict Coronary Artery Disease. PLoS One. 9:e107440;2014.
2. Thiele, GM, Duryee MJ, Anderson DR, Klassen LW, Mohring SM, Yound KA, Benissan-Messan D, Sayles H, Dusad A, Hunter CD, Sokolove J, Robinson W, O’Dell JR, Nicholas AP, Tuma D, Mikuls TR. Malondialdehyde-acetaldehyde adducts (MAA) and anti-MAA antibody in rheumatoid arthritis. Arthritis Rheumatol, 67:645-655; 2015.
3. Nandi SS, Shahshahan H, Thiele GM, Anderson DR, Mishra PK. Induction of autophagy markers is associated with attenuation of miR-133a in diabetic heart failure patients undergoing mechanical unloading. Am J Transl Res. 7:683-96; 2015.
4. Haglund NA, Burdorf A, Jones T, Shostrom V, Um J, Ryan T, Shillcutt S, Fischer P, Cox ZL, Raichlin E, Anderson DR, Lowes BD, Dumitru I. Inhaled Milrinone After Left Ventricular Assist Device Implantation. J Card Fail. 21:792-7; 2015.
5. Antoniak, DT, Duryee MJ, Mikuls TR, Thiele GM, Anderson DR. Aldehyde-modified proteins as mediators of early inflammation in atherosclerotic disease. Free Radic Biol Med. 89:409-418;2015.
6. Carson JS, Xiong W, Dale M, Yu F, Duryee MJ, Anderson DR, Thiele GM, Baxter BT. Antibodies against malondialdehyde-acetaldehyde adducts can help identify patients with abdominal aortic aneurysm. J Vasc Surg. 63:477-85; 2016.
7. Targeted myocardial gene expression in failing hearts by RNA sequencing.  Dhar K, Moulton AM, Rome E, Qiu F, Kittrell J, Raichlin E, Zolty R, Um JY, Moulton MJ, Basma H, Anderson DR, Eudy JD, Lowes BD. J Transl Med. 2016 Nov 25;14(1):327.

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