Research Faculty Bio

Bin Duan, Ph.D.Duan_photo.jpg
Assistant Professor
Division of Cardiovascular Medicine
Mary & Dick Holland Regenerative Medicine Program

Academic office:
982265 Nebraska Medical Center
Omaha, NE 68198-2265

Education:
The University of Hong Kong, PhD, 2010
Tianjin University, MS, 2006
Tianjin University, BS, 2003

Biographical Sketch:

Research Expertise:
The long-term goal of Dr. Duan’s lab (Biomaterials, Biofabrication and Biointerface Lab) is to create multi-scale complexity within engineered tissues to understand the fundamentals of cell-material interactions and mimic the native tissues for biomedical applications with a specific emphasis on tissue disease, tissue regeneration and stem cell bioengineering. Dr. Duan’s research involves: (i) utilizing biofabrication techniques (e.g. 3D bioprinting and electrospinning) to fabricate scaffolds with tailored micro- and macroscopic structures for specific tissue regeneration (e.g. heart valve, osteochondral, and spinal cord); (ii) developing 3D tissue constructs/organoids to investigate the pathogenesis of diseased tissue and examining potential therapeutic remedies; (iii) investigating the interaction of stem cells with defined microenvironments and developing materials-based techniques to control stem cell differentiation.

Selected Publications:

Duan B, Wang M. Customized Ca-P/PHBV nanocomposite scaffolds for bone tissue engineering: Design, fabrication, surface modification and sustained release of growth factor. Journal of the Royal Society Interface, 2010, 7: S615-S629.

Duan B, Kapetanovic E, Hockaday LA, Butcher JT. 3D printed trileaflet valve conduits using biological hydrogels and human valve interstitial cells. Acta Biomaterialia, 2014, 10: 1836-1846.

Duan B, Yin Z, Hockaday LA, Magin R, Butcher JT. Tissue stiffness modulates differentiation and biomechanical remodeling by valve interstitial cells. Acta Biomaterialia, 2016, 36, 42-54.

Duan B. State-of-the-art review of 3D bioprinting for cardiovascular tissue engineering. Annals of Biomedical Engineering, 2017, 45, 195-209.

Wang Y, Wu SH, Kuss MA, Streubel PN, Duan B. Effects of hydroxyapatite and hypoxia on chondrogenesis and hypertrophy in 3D bioprinted ADMSC laden constructs. ACS Biomaterials Science and Engineering, 2017, 3: 826-835.

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