Benita Mcvicker, Ph.D.

Benita McVicker, Ph.D.Associate Professor, Internal Medicine, Gastroenterology & Hepatology

Academic office:
Omaha VA Medical Center
Research (151). R221
4101 Woolworth Ave
Omaha, NE 68105

Education:
University of Nebraska Medical Center, Omaha, NE, PhD, 1997
College of St. Mary, Omaha, NE, PhD, 1987

Areas of Interest
Research in Dr. McVicker’s lab involves the study of (i) altered protein trafficking and hepatocellular injury in animal models of alcohol-associated liver disease; (ii) the role of alcohol in the potentiation of colorectal liver metastases; (iii) the study of hepatic stellate cell transformation and models of liver fibrosis; (iv) targeting profibrotic mechanisms using anti-miRNA nanoparticles; and (v) pre-clinical assessments using human precision-cut liver slices.

Selected Publications
McVicker B, Tuma DJ, Lazure KE, Thomas P, Casey CA. Alcohol, carcinoembryonic antigen processing and colorectal liver metastases. Adv Exp Med Biol. 2015;815:295-311. doi: 10.1007/978-3-319-09614-8_17. Review. PubMed PMID: 25427914

McVicker BL,
Bennett RG. Novel Anti-fibrotic Therapies. Front Pharmacol. 2017;8:318. doi: 10.3389/fphar.2017.00318. eCollection 2017. Review. PubMed PMID: 28620300; PubMed Central PMCID: PMC5449464

Mohr AM, Gould JJ, Kubik JL, Talmon GA, Casey CA, Thomas P, Tuma DJ, McVicker BL. Enhanced colorectal cancer metastases in the alcohol-injured liver. Clin Exp Metastasis. 2017 Feb;34(2):171-184. doi: 10.1007/s10585-017-9838-x. Epub 2017 Feb 6. PubMed PMID: 28168393.

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