Faculty Bio

Ted Mikuls, M.D.Ted  R. Mikuls, M.D., M.S.P.H.
Umbach Professor of Rheumatology, Internal Medicine
Division of Rheumatology

Academic Office:
University of Nebraska Medical Center 
986270 Nebraska Medical Center 
Omaha, NE 68198-6270

Practice Locations:
University of Nebraska Medical Center
Omaha VA Medical Center

1990    B .S., Cum laude,  Santa Clara University, Santa Clara, CA
1995    M.D., High honors,  University of Nebraska Medical Center (UNMC), Omaha, NE
1998    Resident, Internal Medicine UNMC, Omaha, NE
1999    Chief Resident, Internal Medicine UNMC, Omaha, NE
2001    M.S.P.H., Epidemiology,  University of Alabama at Birmingham, Birmingham, AL
2001    Fellow in Rheumatology University of Alabama at Birmingham, Birmingham, AL
2002    Participant, NIH (K-30) Clinical University of Alabama at Research Training Program Birmingham,
            Birmingham, AL 

Current Hospital and Academic Appointments:
Associate Member, Eppley Institute, Cancer Prevention and Control Program
Faculty, University of Nebraska Graduate College
Director / Investigator, Nebraska Arthritis Outcomes Research Center (NAORC)
Director, Omaha VA RA/DMARD Clinic
Professor, UNMC and Omaha VAMC, Omaha, NE
Biographical Sketch:

Dr. Mikuls is a rheumatologist and epidemiologist with research interests focused on the epidemiology, pathogenesis, and outcomes of rheumatoid arthritis (RA) and gout.  He is actively engaged in clinical/translational research activities and receives research funding from the NIH, U.S. Department of Defense, Veterans Affairs, the Rheumatology Research Foundation, and industry.  He has extensive experience conducting multi-center / multidisciplinary trials, serving as the Principal Investigator (PI) for the multicenter Veterans Affairs Rheumatoid Arthritis (VARA) registry since its inception in 2003.  He has served on multiple national study sections including those convened by the NIH, VA, American College of Rheumatology (ACR), and the Arthritis Foundation among others.  He previously chaired the ACR Subcommittee for Practice Guidelines, served on the US FDA’s Arthritis Advisory Committee, and was the lead Editor for the textbook A Color Handbook – Rheumatology.

Research Interests/Current Research:
Outcomes and epidemiology of rheumatoid arthritis
Health outcomes and quality of care in gout

Selected Publications/Current Publications (selected from more than 80): 

  1. Yu Y; Koehn CD; Yue Y; Li S; Thiele GM; Hearth-Holmes MP; Mikuls TR; O Dell JR; Klassen LW; Zhang Z; Su K. Celastrol Inhibits Inflammatory Stimuli-Induced Neutrophil Extracellular Trap Formation. Current Molecular Medicine. 2015
  2. Li S; Yu Y; Yue Y; Liao H; Xie W; Thai J; Mikuls TR; Thiele GM; Duryee MJ; Sayles H; Payne JB; Klassen LW; O Dell JR; Zhang Z; Su K. Autoantibodies from single circulating plasmablasts react with citrullinated antigens and Porphyromonas gingivalis in rheumatoid arthritis. 2015
  3. Navarro-Millan I; Yang S; DuVall SL; Chen L; Baddley J; Cannon GW; Delzell ES; Zhang ES; Safford MM; Patkar NM; Mikuls TR; Singh JA; Curtis JR. Association of hyperlipidemia, inflammation and serological status and coronary heart disease among patients with rheumatoid arthritis: data from the National Veterans Health Administration (Epub ahead of print). Annals of the rheumatic diseases. 2015; 0003-4967
  4. Baker JF; Cannon GW; Ibrahim S; Haroldsen C; Caplan L; Mikuls TR. Predictors of longterm changes in body mass index in rheumatoid arthritis (Epub ahead of print). Journal of Rheumatology. 2015
  5. Payne JB; Golub LM; Thiele GM; Mikuls TR. The link between periodontitis and rheumatoid arthritis: a periodontist's perspective. Current Oral Health Report. 2015; Vol. 2: p. 20-9
  6. Davis ML; Levan T; Yu F; Sayles H; Michaud K; Sokolove J; Robinson W; Thiele GM; Mikuls TR. Associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms and rheumatoid arthritis disease progression: an observational cohort study. International immunopharmacology. 2015; Vol. 24 (2): p. 346. 1567-5769
  7. Anne-Marie Quirke; Karin Lundberg; Jan Potempa; Ted R. Mikuls; Patrick J. Venables. PPAD remains a credible candidate for inducing autoimmunity in rheumatoid arthritis: Comment on the article by Konig et al. Annals of the Rheumatic Diseases. 74 : e7. 2015
  8. Brian W. Coburn; Harlan R. Sayles; Jeffrey B. Payne; Robert S. Redman; Jeffery C. Markt; Mark W. Beatty; Garth R. Griffiths; David J. McGowan; Ted R. Mikuls. Performance of self-reported measures for periodontitis in rheumatoid arthritis and osteoarthritis. Journal of Periodontology. 86 : 16-26. 2015
  9. Michael D. Darley; Dany Saad; Souha Haydoura; David McGowan; Jeffrey B. Payne; Grant W. Cannon; Ted R. Mikuls. Spinal epidural abscess following minimally invasive dental examination in a rheumatoid arthritis patient receiving methotrexate, glucocorticoids, and anti-tumor necrosis factor therapy. Journal of Clinical Rheumatology. 21 : 52-53. 2015
  10. Marshall L.R. Davis; Tricia D. Levan; Fang Yu; Harlan Sayles; Jeremy Sokolove; William Robinson; Kaleb Michaud; Geoffrey M. Thiele; Ted R. Mikuls. Associations of toll-like receptor (TLR)-4 single nucleotide polymorphisms and rheumatoid arthritis disease progression: An observational cohort study. International Immunopharmacology. 24 : 346-352. 2015
  11. Geoffrey M. Thiele; Michael J. Duryee; Daniel R. Anderson; Lynell W. Klassen; Stephen M. Mohring; Kathleen A. Young; Dathe Benissan-Messan; Harlan Sayles; Anand Dusad; Carlos D. Hunter; Jeremy Sokolove; William H. Robinson; James R. O'Dell; Anthony P. Nicholas; Dean J. Tuma; Ted R. Mikuls. Malondialdehyde-acetaldehyde adducts and anti-malondialdehyde-acetaldehyde antibodies in rheumatoid arthritis. Arthritis and Rheumatology. 67 : 645-655. 2015
  12. Nazia Rashid; Brian W. Coburn; Yi-Lin Wu; T.C. Cheetham; Jeffrey R. Curtis; Kenneth G. Saag; Ted R. Mikuls. Modifiable factors associated with allopurinol adherence and outcomes among patients with gout in an integrated healthcare system. Journal of Rheumatology. 42 : 504-512. 2015
  13. Anand Dusad; Geoffrey M. Thiele; Lynell W. Klassen; Dong Wang; Michael J. Duryee; Ted R. Mikuls; Elizabeth B. Staab; Todd A. Wyatt; William W. West; Stephen J. Reynolds; Debra J. Romberger; Jill A. Poole. Vitamin D supplementation protects against bone loss following inhalant organic dust and lipopolysaccharide exposures in mice. Immunologic Research. 2015
  14. Shawneen M. Gonzalez; Jeffrey B. Payne; Fang Yu; Geoffrey M. Thiele; Alan R. Erickson; Paul G. Johnson; Marian J. Schmid; Grant W. Cannon; Gail S. Kerr; Andreas M. Reimold; Jeremy Sokolove; William H. Robinson; Ted R. Mikuls. Alveolar bone loss is associated with circulating anti-citrullinated protein antibody (ACPA) in patients with rheumatoid arthritis. Journal of Periodontology. 86 : 222-231. 2015
  15. Ruchika Patel; Ted R. Mikuls; John S. Richards; Gail Kerr; Grant W. Cannon; Joshua F. Baker. Disease characteristics and treatment patterns in veterans with rheumatoid arthritis and concomitant hepatitis C infection. Arthritis Care and Research. 67 : 467-474. 2015