Professor - Department of Neurological Sciences
Director - Memory Disorders & Behavioral Neurology Program
Director - Behavioral Neurology and Neuropsychiatry Fellowship
Vice Chair - Clinical and Translational Research
|4242 Farnam Street, Suite 650
North Doctor's Tower
Omaha, NE 68131
988440 Nebraska Medical Center
- University of Nebraska School of Medicine, MD (1989)
- University of Michigan Hospitals, Resident (1990-1993)
- University of Michigan Hospitals, Fellowship (1993-1996)
- University of Michigan, School of Public Health, MS (1996-1997)
University of Nebraska Medical Center
Behavioral, Cognitive and Geriatric Neurology
Dr. Murman is a Professor with the Department of Neurological Sciences at the University of Nebraska Medical Center. This institution is also where he received his medical education and he graduated with research honors. His postgraduate training included a Residency in Neurology and a Fellowship in Cognitive Disorders/Geriatric Neurology at the University of Michigan Hospitals in Ann Arbor, Michigan. While a fellow, Dr. Murman completed a masters degree in Clinical Research Design and Biostatistical Analysis form the School of Public Health at the University of Michigan. Prior to coming to UNMC, Dr. Murman was an Assistant and Associate Professor in the Department of Neurology and Ophthalmology at Michigan State University. Dr. Murman joined the faculty at UNMC in 2004.
Dr. Murman is a board-certified Neurologist with subspecialty training and certification in Behavioral Neurology & Neuropsychiatry (BNNP) and Geriatric Neurology. He is a tenured Professor and Vice Chair for Clinical and Translational Research in the Department of Neurological Sciences at UNMC. Dr. Murman directs the Nebraska Medicine Memory Disorders Clinic and the UNMC BNNP Fellowship. The Memory Disorder Clinic evaluates older adults with symptoms of cognitive decline that may be caused by a neurodegenerative disease such as Alzheimer's Disease, Lewy Body Dementias, or Frontotemporal Dementias, or a Vascular Dementia. Dr. Murman provides teaching to medical students, residents, fellows, and graduate students in the areas of Behavioral, Cognitive and Geriatric Neurology. Dr. Murman’s investigator-initiated research has focused on health services research of dementia care and the pharmacoeconomics of treatments for patients with Alzheimer's Disease. In addition, for over 15 years Dr. Murman has actively participated in multi-center, late phase clinical trials of new treatments for AD and for over 25 years has been involved in clinical and translational research studies focused on patients with neurodegenerative diseases such as Alzheimer’s Disease, Parkinson’s Disease, Lewy Body Dementias and Frontotemporal Dementias.
Dr. Murman's Active Clinical Research:
Anti-Amyloid Treatment in Asymptomatic Alzheimer's Disease (A4 Study)
A phase 3, multi-center, randomized, double-blind, parallel-group, placebo-controlled trial to evaluate the efficacy and safety of sodium oligomannate (GV-971) in treatment of mild to moderate Alzheimer’s disease. (Green Memory Study)
ADvance II: A 12-month double-blind, randomized, controlled study to evaluate the safety and efficacy of deep brain stimulation of the fornix (DBS-f) in patients with mild probable Alzheimer’s disease.
A phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group, efficacy and safety study of gantenerumab in patients with early (prodromal to mild) Alzheimer’s disease. The “Graduate II Study.”
Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (the “LEARN Study”).
Murman, DL. The impact of age on cognition. Seminars in Hearing, 2015. 36(3) 111-121.
Michaud TL, Su D, Siahpush M, Murman DL. The risk of incident MCI and the progression to dementia by MCI subtypes. Dement Geriatr Cogn Disord Extra 2017; 7:15-29.
Michaud TL, High R, Charlton ME, Murman DL. Dependence stage and pharmacoeconomic outcomes in patients with Alzheimer’s disease. Alzheimer Dis Assoc Disord 2017; 31:209-217.
Michaud TL, Siahpush M, Farazi PA, Kim J, Yu F, Su D, Murman DL. The association between body mass index and cognitive, functional, and behavioral declines in incident dementia. J Alzheimers Dis 2018; 66(4):1507-1517.
Alwatban M, Murman DL, Bashford G. Cerebrovascular reactivity impairment in preclinical Alzheimer’s disease. J Neuroimaging 2019; 29(4):493-498.
Wiesman AI, Murman DL, May PE, Schantell M, Losh RA, Johnson HJ, Willet MP, Eastman JA, Christopher-Hayes NJ, Knott NL, Houseman LL, Wolfsen SL, Losh KL, Johnson CM, Wilson TW. Spatio-spectral relationships between pathological neural dynamics and cognitive impairment along the Alzheimer’s disease spectrum. Alzheimer’s Dement 2021; 31;13(1):e12200. doi: 10.1002/dad2.12200. PMID: 34095434.
Phipps CJ, Murman DL, Warren DE. Stimulating Memory: Reviewing interventions using repetitive transcranial magnetic stimulation to enhance or restore memory abilities. Brain Sci 2021;11(10):1283. doi:10.3390/brainsci11101283. PMID 34679348.
Wiesman AI, Murman DL, Losh RA, Schantell M, Christopher-Hayes NJ, Johnson HJ, Willett MP, Wolfson SL, Losh KL, Johnson DM, May PE, Wilson TW. Spatially resolved neural slowing predicts impairment and amyloid burden in Alzheimer’s disease. Brain 2022; online ahead of print; doi: 10.1093/brain/awab430. PMID: 35088842.Book Chapters:
Eggenberger E, Murman DL. Prion Diseases and Other Rapidly Progressive Dementias. In: Schapira A, Wszolek Z, Dawson TM, Wood N eds. Neurodegeneration. John Wiley & Sons, Ltd. 2017.
Murman DL. Neurology. In: Harper, GM, Lyons WL, Potter JF, et al, eds. Geriatric Review Syllabus: A Core Curriculum in Geriatric Medicine, 11th Edition. New York: American Geriatric Society; 2022.
Murman, DL, Pichler, M. Stroke and Cerebrovascular Disease. In: Harper GM, Lyons, WL, Potter JF, et al, eds. Geriatric Review Syllabus: A Core Curriculum in Geriatric Medicine, 11th Edition. New York: American Geriatric Society; 2022.