UNMC_Acronym_Vert_sm_4c
University of Nebraska Medical Center

Suvendra Bhattacharyya, MSc, PhD

Education

  • PhD in Life Sciences, Indian Institute of Chemical Biology, Jadavpur University, Kolkata, India 2004
  • MSc in Biochemistry with Physics and Mathematics, Presidency College, University of Calcutta , India, 1996
Honors, Awards, Fellowships and Certifications

2023                JC Bose Fellowship Award, Science and Engineering Research Board

2021                Sun Pharma Award in Medical Sciences, Basic Research

2021                Elected Fellow of the Indian National Science Academy, New Delhi (INSA)

2019                Members of the Joint Science Education Panel of Indian Academy of Sciences,

2018                Khosla Science Award, IIT Roorkee

2017                CDRI Award for Excellence in Drug Research by CSIR-CDRI Lucknow

2017                Members of the Senate of Academy of Scientific and Innovative Research (AcSIR), India

2017                Elected Fellow of the National Academy of Sciences India (NASI)

2017                Elected fellow of the Indian Academy of Sciences, Bangalore (IAS)

2016               Shanti Swarup Bhatnagar Prize in Biological Sciences 2016 by CSIR,  Govt. of India (Highest Science award for Scientist working in India)

2016                National Bioscience Award for Career Development by Dept. of Biotechnology, Government  of India

2016                Elected Fellow of the West Bengal Academy of Science and Technology, India

2016                Prof B K Bachhawat Memorial Travel Award

2016                Elected Member of the Guha Research Conference, India         

2015                Swarna Jayanti Fellowship of Dept of Science and Technology, Govt. of India

2015                NASI-Scopus Young Scientist Award from NASI, India and Scopus, India

2004                AAAS/Science Young Scientist Award given for best PhD work at global level l by AAAS/Science, USA

2004                INSA Young Scientist Award (Highest Science Award for researcher working in India below 32 years)

1998                All India First Rank in GATE 1998 examination in Life Sciences

Selected Publications
  1. Hom Choudhury S, Bhattacharjee S, Mukherjee K, Bhattacharyya SN. Human antigen R transfers miRNA to Syntaxin 5 to synergize miRNA export from activated macrophages.  J Biol Chem. 2024 Apr;300(4):107170. doi: 10.1016/j.jbc.2024.107170. PMID: 38492777
  2. Ghosh S, Hom Choudhury S, Mukherjee K, Bhattacharyya SN. HuR-miRNA complex activates RAS GTPase RalA to facilitate endosome targeting and extracellular export of miRNAs. J Biol Chem. 2024 Mar;300(3):105750. doi: 10.1016/j.jbc.2024.105750. PMID: 38360271
  3. Bandyopadhyay D, Basu S, Mukherjee I, Chakrabarti S, Chakrabarti P, Mukherjee K, Bhattacharyya SN. Accelerated Export of Dicer1 from Lipid-Challenged Hepatocytes Buffers Cellular miRNA-122 Levels and Prevents Cell Death. J Biol Chem. 2023 Jun 30:104999. doi: 10.1016/j.jbc.2023.104999. Online ahead of print. PMID: 37394005
  4. Ganguly S, Ghoshal B, Banerji I, Bhattacharjee S, Chakraborty S, Goswami A, Mukherjee K, Bhattacharyya SN.Leishmania survives by exporting miR-146a from infected to resident cells to subjugate inflammation. Life Sci Alliance. 2022 Jun;5(6). doi: 10.26508/lsa.202101229. Print 2022 Jun. PubMed PMID: 35210329; PubMed Central PMCID: PMC8881743. 
  5. De D, Bhattacharyya SN.Amyloid-β oligomers block lysosomal targeting of miRNPs to prevent miRNP recycling and target repression in glial cells.J Cell Sci. 2021 Jun 1;134(11). doi: 10.1242/jcs.258360. Epub 2021 Jun 7. PubMed PMID: 34096603. 
  6. De D, Mukherjee I, Guha S, Paidi RK, Chakrabarti S, Biswas SC, Bhattacharyya SN.Rheb-mTOR activation rescues Aβ-induced cognitive impairment and memory function by restoring miR-146 activity in glial cells. Mol Ther Nucleic Acids. 2021 Jun 4;24:868-887. doi: 10.1016/j.omtn.2021.04.008. eCollection 2021 Jun 4. PubMed PMID: 34094708; PubMed Central PMCID: PMC8141608. 
  7. Ghoshal B, Bertrand E, Bhattacharyya SN.Non-canonical argonaute loading of extracellular vesicle-derived exogenous single-stranded miRNA in recipient cells. J Cell Sci. 2021 May 1;134(9). doi: 10.1242/jcs.253914. Epub 2021 May 17. PubMed PMID: 33785534. 
  8. Goswami A, Mukherjee K, Mazumder A, Ganguly S, Mukherjee I, Chakrabarti S, Roy S, Sundar S, Chattopadhyay K, Bhattacharyya SN.MicroRNA exporter HuR clears the internalized pathogens by promoting pro-inflammatory response in infected macrophages. EMBO Mol Med. 2020 Mar 6;12(3):e11011. doi: 10.15252/emmm.201911011. Epub 2020 Feb 7. PubMed PMID: 32031337; PubMed Central PMCID: PMC7059013. 
  9. Mukherjee K, Ghoshal B, Ghosh S, Chakrabarty Y, Shwetha S, Das S, Bhattacharyya SN.Reversible HuR-microRNA binding controls extracellular export of miR-122 and augments stress response. EMBO Rep. 2016 Aug;17(8):1184-203. doi: 10.15252/embr.201541930. Epub 2016 Jul 11. PubMed PMID: 27402548; PubMed Central PMCID: PMC4967961. 
  10. Bose M, Bhattacharyya SN.Target-dependent biogenesis of cognate microRNAs in human cells. Nat Commun. 2016 Jul 22;7:12200. doi: 10.1038/ncomms12200. PubMed PMID: 27448149; PubMed Central PMCID: PMC4961841. 
  11. Ghosh J, Bose M, Roy S, Bhattacharyya SN.Leishmania donovani targets Dicer1 to downregulate miR-122, lower serum cholesterol, and facilitate murine liver infection. Cell Host Microbe. 2013 Mar 13;13(3):277-88. doi: 10.1016/j.chom.2013.02.005. PubMed PMID: 23498953; PubMed Central PMCID: PMC3605572.
  12. Bhattacharyya SN, Habermacher R, Martine U, Closs EI, Filipowicz W. Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell. 2006 Jun 16;125(6):1111-24. doi: 10.1016/j.cell.2006.04.031. PubMed PMID: 16777601.