Yu Lei, Ph.D.

Yu Lei, Ph.D.Assistant Professor

Ph.D. in Applied Physics; Chinese Academy of Sciences; China, 2003
M.S.  in Medical Physics, Wayne State University; 2009 
B.En. in Optics; ChangChun Institute of Optics and Fine Mech.; China, 1997

American Board of Radiology - Therapeutic Radiological Physics

Professional Memberships:
American Association of Physicists in Medicine (AAPM)
Sigma Xi

Clinical & Research Interests:
Brachytherapy (HDR and LDR)
3D/IMRT treatment planning
Y-90 Radioembolization
SRS/SBRT techniques
Radiation dosimetry 
Linac QA and HDR system

Research Projects:
Quality assurance and safety improvement in radiotherapy; information technology in radiotherapy; application of statistical learning in radiotherapy.


  1. "A Quality Assurance Approach for Linear Accelerator Mechanical Isocenters with Portal Images" Q. Fan, S. Zhou, Y. Lei, S. Li, M. Zhang. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology, 7, 100-114.
  2. "A Feasibility Study of Applying Thermal Imaging to Assist Quality Assurance of High Dose Rate Brachytherapy" X. Zhu, Y. Lei, D. Zheng, S. Li, V. Verma, M. Zhang, Q. Zhang, X. Tang, J. Lian, S. Chang, H. Song, S. Zhou, C. Enke. Cancer Transl Med 2017; 3: 159-66.
  3. "Using weighted power mean for equivalent square estimation" S. Zhou, Q. Wu, X. Li, R. Ma, D. Zheng, S. Wang, M. Zhang, S. Li, Y. Lei, Q. Fan, M. Hyun, T. Diener, C. Enke, J. Appl. Clin. Med. Phys. 2017 Nov; 18(6): 194-199.
  4. "Estimation of internal organ motion-induced variance in radiation dose in non-gated radiotherapy" S. Zhou, X. Zhu, M. Zhang, D. Zheng, Y. Lei, S. Li, N. Bennion, V. Verma, W. Zhen, C. Enke, Phys. Med. Biol. 61(23) (2016): 8157.
  5. "Automatic planning on hippocampal avoidance whole-brain radiotherapy" S. Wang, D. Zheng, C. Zhang, R. Ma, N.R. Bennion, Y. Lei, X. Zhu, C.A. Enke, S. Zhou, Med Dosim. 42(1) (2016):63.
  6. "Automated survey of 8000 plan checks at eight facilities", T. Halabi, HM Lu, DA Bernard, JC Chu, MC Kirk, RJ Hamilton, Y. Lei, J. Driewer, Med. Phys. 43(9) (2016): 4966.
  7. "Target dose conversion modeling from pencil beam (PB) to Monte Carlo (MC) for lung SBRT", D. Zheng, X. Zhu, Q. Zhang, X. Liang, W. Zhen, C. Lin, V. Verma, S. Wang, A. Wahl, Y. Lei, S. Zhou, C. Zhang, Radiat Oncol. (2016): 11:83.
  8. "Investigations of a GPU-based Levy-Firefly Algorithm for Constrained Optimization of Radiation Therapy Treatment Planning" G. Kalantzis, C. Shang, Y. Lei, T. Leventoun. Swarm and Evolution Computation 26 (2016): 191.
  9. "Technical Note: Fabricating Cerrobend grids with 3D printing for spatially modulated radiation therapy:  A feasibility study" X. Zhu, J. Driewer, S. Li, V. Verma, Y. Lei, M. Zhang, Q. Zhang, D. Zheng, T. Cullip, S. Chang, A. Wang, S. Zhou, C. Enke. Med. Phys. 42 (2015): 6269.
  10. "A new variable for SRS plan quality evaluation based on normal tissue sparing: the effect of prescription isodose levels" Q. Zhang, D. Zheng, Y. Lei, et al. Br J Radiol 87 (2014): 20140362.
  11. "A Self-tuned Bat Algorithm for Optimization in Radiation Therapy Treatment Planning" G. Kalantzis, Y. Lei, Software Engineering, Artificial Intelligence, Networking and Parallel/Distributed Computing 2014: 1-6.