Dandan Zheng, Ph.D.

Dandan Zheng, Ph.D.Associate Professor & Physics Residency Program Director

Education:
Ph.D. in Applied Science Engineering; Univeristy of California at Davis; 2007 
MS in Biomedical Engineering; University of California at Davis; 2007
BS in Biological Sciences; University of Science & Technology of China; 2003

Certifications:
American Board of Radiology - Therapeutic Radiological Physics

Professional Memberships:
American Association of Physicists in Medicine (AAPM)
American Society for Therapeutic Radiation Oncology (ASTRO)

Clinical & Research Interests:
Brachytherapy (HDR and LDR)
3D/IMRT treatment planning
SRS/SBRT/IGRT techniques
Radiation dosimetry
QA of linac and HDR system

Research Projects:
Dr. Zheng’s research interests include advanced treatment planning, dose calculation, and motion management for stereotactic body radiotherapy and stereotactic radiosurgery; image-guided adaptive radiotherapy and related imaging modalities; radiomics analysis for personalized cancer diagnosis and therapy; and brachytherapy.

Publications:

  1. Zheng, J. Ford, J. Lu, D. Lazos, J. Hugo, D. Pokhrel, L. Zhang, and J. Williamson, "Bow-tie wobble artifact: Effect of source assembly wobble on cone-beam CT", Medical Physics 38, 2508 -2514 (2011)
  2. S. Liang, D. Zheng, C. Zhang, D.M. Standley, "Fast and accurate prediction of protein side-chain conformations", Bioinformatics 27 (20), 2913-2914 (2011)
  3. J. Ford, D. Zheng, and J. Williamson, "Estimation of CT cone-beam geometry using a novel method insensitive to phantom fabrication inaccuracy: Implications for isocenter localization accuracy", Medical Physics 38, 2829-2840 (2011)
  4. D. Zheng, and D. Todor, "A novel method for accurate needle tip identification in trans-rectal ultrasound-based prostate high dose rate brachytherapy", Brachytherapy 10 (6), 466-473 (2011)
  5. D. Zheng, “The Use of Cone Beam Computed Tomography in Image-Guided Radiotherapy”, Radiology: Open Access doi:10.4172/roa.1000e104 (2012)
  6. D. Zheng, J. Lu, A. Jefferson, C. Zhang, J. Wu, W. Sleeman, E. Weiss, N. Dogan, S. Song, and J. Williamson, "A protocol to extend the longitudinal coverage of on-board cone-beam CT", Journal of Applied Clinical Medical Physics, Journal of Applied Clinical Medical Physics, Vol 13, No 4, 141-151 (2012)
  7. B. Yao; D. Zheng; S. Liang; C. Zhang. "Conformational B-Cell Epitope Prediction on Antigen Protein Structures: A Review of Current Algorithms and Comparison with Common Binding Site Prediction Methods" PLoS ONE. 8 : 2013
  8. J J Souchek, M J Baine, C Lin, S Rachagani, S Gupta, S Kaur, K Lester, D Zheng, S Chen, L Smith, A Lazenby, S L Johansson, M Jain, and S K Batra, "Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation", British Journal of Cancer (2014) 111, 1139–1149.
  9. Q. Zhang, D. Zheng, L. Yu, B. Morgan, J. Driewer, M. Zhang, S. Li, S. Zhou, W. Zhen, R. Thompson, A. Wahl, C. Lin, C. Enke, "A new variable for SRS plan quality evaluation based on normal tissue sparing: The Effect of Prescription Isodose Levels", British Journal of Radiology, 2014, (87), 1043.
  10. X. Zhu, J. Driewer, S. Li, V. Verma, Y. Lei, M. Zhang, Q. Zhang, D. Zheng, T. Cullip, S. X. Chang, A. Z. Wang, S. Zhou and C. A Enke, "Technical Note: Fabricating Cerrobend grids with 3D printing for spatially modulated radiation therapy: A feasibility study", Med. Phys. 42, 6269 (2015)
  11. X. Liang, J. Penagaricano, D. Zheng, S. Morrill, X. Zhang, P. Corry, R. J.Griffin, E. Y. Han, M. Hardee, V. Ratanatharathom, "Radiobiological impact of dose calculation algorithms on biologically optimized IMRT lung stereotactic body radiation therapy plans", Radiation Oncology, 11:10  (2016)
  12. D. Zheng, Q. Zhang, X. Liang, X. Zhu, V. Verma, S. Wang, and S. Zhou, "Effect of the normalized prescription isodose line on the magnitude of Monte Carlo vs. pencil beam target dose differences for lung stereotactic body radiotherapy", Journal of Appllied Clinical Medical Physics 17:4 (2016)
  13. D. Zheng, X. Zhu, Q. Zhang, X. Liang, W. Zhen,  C. Lin, V. Verma, S. Wang, A. Wahl, Y. Lei, S. Zhou and C. Zhang, "Target dose conversion modeling from pencil beam (PB) to Monte Carlo (MC) for lung SBRT", Radiation Oncology 11:83 (2016)
  14. S. Zhou, X. Zhu, M. Zhang, D. Zheng, Y. Lei, S. Li, N. Bennion, V. Verma, W. Zhen and C. Enke, "Estimation of internal organ motion-induced variance in radiation dose in non-gated radiotherapy", Physics in Medicine and Biology 61:23 (2016)
  15. J. Gruhl, D. Zheng, J Longo, C. Enke, and A. Wahl, "Comparing organ-at-risk doses for high-dose rate vaginal brachytherapy between three different planning workflows", Brachytherapy, In press (2016)