Iraklis Pipinos, MD, FACS

Iraklis Pipinos, MDProfessor
Department of Surgery
Division of Vascular Surgery
University of Nebraska Medical Center
982500 Nebraska Medical Center
Omaha, NE 68198-2500, USA
Phone: 402-559-9549
Fax: 402-559-8985

Curriculum Vitae

University of Crete, School of Medicine, Crete, Greece, MD

Henry Ford Hospital, Dept. of Surgery, Detroit, Michigan

Vascular Surgery: Henry Ford Hospital, Division of Vascular Surgery
Endovascular Surgery: Stanford University, Division of Vascular Surgery, Stanford, CA

Board Certification:
American Board of Surgery
American Board of Surgery Vascular Surgery

Academic Appointment:
Professor of Surgery

Vascular Surgery
Endovascular Surgery
Complex Aortic Surgery

Research Interests:
Open versus endovascular repair for abdominal aortic aneurysms
Mitochondrial dysfunction in chronically ischemic skeletal muscle
Carotid stenting
Walking impairment in claudication


  • Becker RA, Cluff K, Duraisamy N, Mehraein H, Farhoud H, Collins T, Casale GP, Pipinos II, Subbiah J.  Optical probing of gastrocnemius in patients with peripheral artery disease characterizes myopathic biochemical alterations and correlates with stage of disease.  Physiol Rep. 2017 Mar;5(5). pii: e13161. Abstract
  • Powell JT, Sweeting MJ, Ulug P, Blankensteijn JD, Lederle FA, Becquemin JP, Greenhalgh RM; EVAR-1, DREAM, OVER and ACE Trialists.  Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years.  Br J Surg. 2017 Feb;104(3):166-178.  Abstract
  • Long CA, Timmins LH, Koutakis P, Goodchild TT, Lefer DJ, Pipinos II, Casale GP, Brewster LP.  An endovascular model of ischemic myopathy from peripheral arterial disease.  J Vasc Surg. 2016 Sep 29. pii: S0741-5214(16)31096-5.  Abstract
  • Myers SA, Applequist BC, Huisinga JM, Pipinos II, Johanning JM.  Gait kinematics and kinetics are affected more by peripheral arterial disease than by age.  J Rehabil Res Dev. 2016;53(2):229-38.  Abstract
  • Gupta PK, Ramanan B, Grossman L, Gupta H, Fang X, MacTaggart JN, Lynch TG, Baxter BT, Pipinos II.  Outcomes of Aortic Surgery for Abdominal Aortic Graft Infections.  Vasc Endovascular Surg. 2016 Apr 21.  Abstract
  • Ha DM, Carpenter LC, Koutakis P, Swanson SA, Zhu Z, Hanna M, DeSpiegelaere HK, Pipinos II, Casale GP.  Transforming growth factor-beta 1 produced by vascular smooth muscle cells predicts fibrosis in the gastrocnemius of patients with peripheral artery disease.  J Transl Med. 2016 Feb 4;14:39.  Abstract
  • Myers SA, Huben NB, Yentes JM, McCamley JD, Lyden ER, Pipinos II, Johanning JM.  Spatiotemporal Changes Posttreatment in Peripheral Arterial Disease.  Rehabil Res Pract. 2015;2015:124023.  Abstract
  • Rand TJ, Wurdeman SR, Johanning JM, Pipinos II, Myers SA.  Increased minimum toe clearance variability in patients with peripheral arterial disease.  Med Eng Phys. 2015 Dec;37(12):1141-5.  Abstract
  • Polhemus DJ, Bradley JM, Islam KN, Brewster LP, Calvert JW, Tao YX, Chang CC, Pipinos II, Goodchild TT, Lefer DJ.  Therapeutic potential of sustained-release sodium nitrite for critical limb ischemia in the setting of metabolic syndrome.  Am J Physiol Heart Circ Physiol. 2015 Jul 1;309(1):H82-92.  Abstract
  • Koutakis P, Myers SA, Cluff K, Ha DM, Haynatzki G, McComb RD, Uchida K, Miserlis D, Papoutsi E, Johanning JM, Casale GP, Pipinos II.  Abnormal myofiber morphology and limb dysfunction in claudication.  J Surg Res. 2015 Jun 1;196(1):172-9.  Abstract
  • Koutakis P, Miserlis D, Myers SA, Kim JK, Zhu Z, Papoutsi E, Swanson SA, Haynatzki G, Ha DM, Carpenter LA, McComb RD, Johanning JM, Casale GP, Pipinos II.  Abnormal accumulation of desmin in gastrocnemius myofibers of patients with peripheral artery disease: associations with altered myofiber morphology and density, mitochondrial dysfunction and impaired limb function.  J Histochem Cytochem. 2015 Apr;63(4):256-69.  Abstract
  • Melin AA, Schmid KK, Lynch TG, Pipinos II, Kappes S, Longo GM, Gupta PK, Johanning JM.  Preoperative frailty Risk Analysis Index to stratify patients undergoing carotid endarterectomy.  J Vasc Surg. 2015 Mar;61(3):683-9.  Abstract
  • Kamenskiy AV, Pipinos II, Carson JS, MacTaggart JN, Baxter BT.  Age and disease-related geometric and structural remodeling of the carotid artery.  J Vasc Surg. 2015 Dec;62(6):1521-8.  Abstract
  • Kamenskiy AV, Pipinos II, Dzenis YA, Phillips NY, Desyatova AS, Kitson J, Bowen R, MacTaggart JN.  Effects of age on the physiological and mechanical characteristics of human femoropopliteal arteries.  Acta Biomater. 2015 Jan;11:304-13.  Abstract
  • Yanala UR, Johanning JM, Pipinos II, Larsen G, Velander WH, Carlson MA.  Development of a fatal noncompressible truncal hemorrhage model with combined hepatic and portal venous injury in normothermic normovolemic swine.  PLoS One. 2014 Sep 24;9(9):e108293.  Abstract

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