Booster vaccines reduced the risk of COVID‑19-related hospitalization and death, according to a new study of over 3 million adults who had the autumn 2022 vaccine in England. The research, led by the universities of Bristol and Oxford, provides further evidence of the effectiveness of booster vaccination against COVID‑19. The study is published in Vaccine. The research also found that this effectiveness was similar for Moderna (BA.1 mRNA-1273) and Pfizer-BioNTech (BA.1 BNT162b2) booster vaccines, but that protection declined over time.
Previous work has shown the initial COVID‑19 vaccination was effective in reducing the risk of hospitalization and death due to COVID‑19. This latest research, carried out at the National Institute for Health and Care Research (NIHR) Bristol Biomedical Research Centre (BRC), looked at the impact of giving people a booster vaccine.