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University of Nebraska Medical Center

US government exercises $144m option for smallpox/mpox vaccine contract

Pharmaceutical Technology

The options are for the freeze-dried version of Bavarian Nordic’s Jynneos, a formulation that allows easier stockpiling.

Amid a US measles outbreak the US government has placed a $143.6m order for Bavarian Nordic’s smallpox/mpox jab Jynneos to bolster its infectious disease preparedness.

The order is part of a ten-year contract awarded to vaccine-developer Bavarian Nordic by the US government’s Biomedical Advanced Research and Development Authority (BARDA). The agreement between the pair includes options valued at $299m for the fill and finish of freeze-dried vaccines. Deliveries under the new contract options are planned for 2026.

The additional options exercised by BARDA support the manufacturing and supply of freeze-dried Jynneos by conversion of bulk vaccine, as well as supplemental payments for all doses procured under the freeze-dried contract. The latter was triggered after the freeze-dried formulation’s extended shelf life was demonstrated.

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