Vax Before Travel The WHO Director-General recently determined that the upsurge of mpox cases in Africa continues to meet the criteria of a public health emergency of international concern and issued temporary recommendations to States Parties as of July 10, 2025.
The first human case of mpox was recorded in 1970 in the Democratic Republic of the Congo, which has subsequently spread to other central and western African countries.
According to the U.S. Centers for Disease Control and Prevention (CDC), outbreaks of clade II mpox have been reported in Liberia and Sierra Leone, where mpox is endemic.
The CDC’s updated Level 2 – Practice Enhanced Precautions, Travel Health Advisory states that, unlike the ongoing global clade II mpox outbreak, which began in May 2022, these outbreaks have affected males and females approximately equally.