University of Nebraska Medical Center

Karuna Rasineni, PhD

Assistant Professor, Division of Gastroenterology and Hepatology


Karuna Rasineni, PhD

Dr. Rasineni has been working in the field of alcoholic and non-alcoholic liver disease, with special interest in the role of ghrelin hormone in development of fatty liver. She is also interested in a role for ghrelin in impairing adipose tissue metabolism in the development of hepatic steatosis during the pathogenesis of both alcohol and/or non-alcoholic fatty liver disease. 

Dr. Rasineni has a broad background in endocrinology and metabolic diseases with specific training and expertise. These studies are part of an overall goal to investigate organ interactions particularly stomach-pancreas-liver cross talks in the development of fatty liver disease. Her studies are important since a proper understanding of the mechanisms involved in ghrelin mediated dysregulation of adipose metabolism would provide valuable information for designing effective therapeutic strategies against fatty liver disease development.


  • Alcohol-associated fatty liver disease
  • Non-alcoholic fatty liver disease
  • Aging and its effects on alcohol-associated fatty liver disease
Active Grant Support


  • "Altered Lipid Droplet Trafficking Role in Alcoholic Fatty Liver Disease" Other (Casey), DHHS/NIH/NIAAA
  • "Role of alcohol-induced ghrelin in modulating organ cross-talk to promote the development of fatty liver disease" Principal Investigator, DHHS/NIH/NIAAA
  • "IPA for Karuna Rasineni" Other (Casey), VA Medical Center - Omaha
  • "Pancreas-Adipose-Liver Axis: Role of Ghrelin and Insulin in Alcoholic Fatty Liver" Principal Investigator, DHHS/NIH/NIAAA


  • "Alcohol Center Of Research-Nebraska (ACORN)" Co-Investigator (Casey), DHHS/NIH/NIAAA
  • BS: Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India, 2001
  • MSC: Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India, 2003
  • M. Phil: Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India, 2006
  • PhD: Sri Krishnadevaraya University, Anantapur, Andhra Pradesh, India, 2009