Assistant Professor - Department of Neurological Sciences
Director - Seahorse Core
Durham Research Center, 3013
985800 Nebraska Medical Center
Omaha, NE 68198-5800
My major focus is the role of mitochondrial dysfunction and altered energy metabolism in the context of neurodegenerative diseases and aging. Mitochondrial abnormalities are implicated to play a major role in aging and age-related neurodegenerative diseases, such as Alzheimer’s disease and Parkinson’s disease (PD). Further, HIV appears to increase the risk for several age-associated diseases, including cognitive impairment and antiretroviral drugs are associated with neurotoxic side effects, including mitochondrial toxicity, which likely contribute to the development of HIV-associated neurocognitive disorders (HAND). The goal of my work in the laboratory is to elucidate the mechanisms leading to alterations in mitochondrial energy metabolism in order to develop therapeutic strategies to treat or prevent neurodegeneration.
Publications by Dr. Stauch in PubMed.