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Associate Professor of Surgery |
Graduate: | University of Alberta |
Fellowship: | University Nebraska Medical Center |
Board Certification: |
American Board of Surgery, Royal College of Physicians and Surgeons of Canada |
Academic Appointment: |
2017 – University of Nebraska Medical Center. |
Special Interests: |
Clinical interest in liver and pancreatic surgery as well as liver and intestinal transplantation. Research focus on the clinical outcomes of intestinal transplantation, specifically exploring strategies to optimize graft function and patient survival. |
Publications:
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Kidney injury and status 1 liver transplantation: Outcomes, kidney function, and listing for kidney transplantation
Cloonan, D. J., Cloonan, M. R., Westphal, S. G., Dageforde, L. A. & Merani, S., Apr 2023 -
Kidney injury and status 1 liver transplantation: Outcomes, kidney function, and listing for kidney transplantation
Cloonan, D. J., Cloonan, M. R., Westphal, S. G., Dageforde, L. A. & Merani, S., Feb 13 2023 -
Unusual dMMR Phenotype Locally Advanced Pancreatic Ductal Adenocarcinoma with Germline and Somatic BRCA2 Mutation in a Jehovah Witness Patient
Copur, M. S., Tun, S. M., Vargas, L., Merani, S., Wedel, W., Duckert, R., Horn, A., Lintel, N., Herold, D. & Lavudi, S., Mar 2023 -
A North American single-center experience with liver transplantation using thoracoabdominal normothermic regional perfusion for donation after circulatory death
Merani, S., Urban, M., Um, J. Y., Maskin, A., Vargas, L. M., Castleberry, A. W., Mercer, D. F., Grant, W. & Langnas, A. N., Feb 2022, -
Cholecystectomy prior to short bowel syndrome does not alter nutritional prognosis
Thompson, J. S., Rochling, F. A., Lyden, E., Merani, S., Vargas, L. M., Grant, W. J., Langnas, A. N. & Mercer, D. F., 2022 -
Impact of Portable Normothermic Blood-Based Machine Perfusion on Outcomes of Liver Transplant: The OCS Liver PROTECT Randomized Clinical Trial
Markmann, J. F., Abouljoud, M. S., Ghobrial, R. M., Bhati, C. S., Pelletier, S. J., Lu, A. D., Ottmann, S., Klair, T., Eymard, C., Roll, G. R., Magliocca, J., Pruett, T. L., Reyes, J., Black, S. M., Marsh, C. L., Schnickel, G., Kinkhabwala, M., Florman, S. S., Merani, S., Demetris, A. J., & 15 others, Mar 2022 -
Liver transplantation as a new standard of care in patients with perihilar cholangiocarcinoma? Results from an international benchmark study
Breuer, E., Mueller, M., Doyle, M. B., Yang, L., Murad, S. D., Anwar, I. J., Merani, S., Limkemann, A., Jeddou, H., Kim, S. C., López-López, V., Nassar, A., Hoogwater, F. J. H., Vibert, E., de Oliveira, M. L., Cherqui, D., Porte, R. J., Magliocca, J. F., Fischer, L., Fondevila, C., & 15 others, Nov 1 2022. -
Presentation of preclinical gastrointestinal anatomy via laparoscopic simulation
McCumber, T. L., Mott, J. L., Merani, S. & Rochling, F. A., Oct 2022 -
Successful lung transplantation with graft recovered after thoracoabdominal normothermic perfusion from donor after circulatory death
Urban, M., Castleberry, A. W., Markin, N. W., Chacon, M. M., Strah, H. M., Um, J. Y., Berkheim, D., Merani, S. & Siddique, A., Jan 2022 -
Thoracoabdominal Normothermic Perfusion in Donation After Circulatory Death
Urban, M., Castleberry, A. W., Duncan, K. F., Markin, N. W., Chacon, M. M., Siddique, A., Merani, S., Robertson, R., Fristoe, L. & Um, J. Y., Jun 2022. -
Immune function and infectious complications in children with jejunoileal atresia
Prachuapthunyachart, S., Merani, S., Cloonan, M., Langnas, A. N., Quiros-Tejeira, R. E. & Vo, H. D., Mar 2021 -
Increased Morbidity and Mortality of Patients with Non-cirrhotic Portal Vein Thrombosis After Abdominal and Pelvic Surgeries: a Study of the National Inpatient Sample 2002 to 2015
Manatsathit, W., Patel, K., Enke, T., Sayles, H., Jophlin, L. L. & Merani, S., Aug 2021 -
Not as Rare as Initially Described: Transplant Ureter Incarceration Within Inguinal Hernia. Two Cases, Literature Review, and Management Algorithm
Merani, S., Aufhauser, D. D., Maskin, A. T., Mezrich, J. & Al-Adra, D., Sep 2021 -
The impact of multi-organ transplant allocation priority on waitlisted kidney transplant candidates
Westphal, S. G., Langewisch, E. D., Robinson, A. M., Wilk, A. R., Dong, J. J., Plumb, T. J., Mullane, R., Merani, S., Hoffman, A. L., Maskin, A. & Miles, C. D., Jun 2021 -
Central diabetes insipidus unmasked by kidney transplantation: a case report and literature review
Merani, S., Emuron, D., Westphal, S. & Hoffman, A., Sep 2020 -
Hereditary vs familial pancreatic cancer: Associated genetic syndromes and clinical perspective
Copur, M. S., Talmon, G. A., Wedel, W., Hart, J. D., Merani, S. & Vargas, L. M., Jun 2020 -
Including colon in intestinal transplantation: a focus on post-transplant renal function – a retrospective study
Ewald, C., Swanson, B. J., Vargas, L., Grant, W. J., Mercer, D. F., Langnas, A. N. & Merani, S., Feb 1 2020 -
Pancreatic Neuroendocrine Tumor With Humoral Hypercalcemia and High Tumor PD-L1 Score
Copur, M. S., Vargas, L., Wedel, W., Merani, S., Cushman-Vokoun, A. & Drincic, A., Dec 7 2020 -
Viral enteritis in intestinal transplant recipients
Servais, A. M., Keck, M., Leick, M., Mercer, D. F., Langnas, A. N., Grant, W. J., Vargas, L. M., Merani, S. & Florescu, D. F., Apr 1 2020 -
Biliary cancer: Current multimodality treatment and future directions
Copur, M. S., Merani, S. & Vargas, L. M., Sep 2019 -
Double Obstruction Following Third Renal Transplant: A Case Report
Anderson, B., Merani, S. & Maskin, A., Nov 2019 -
Failure of abdominal wall closure after intestinal transplantation: Identifying high-risk recipients
Cloonan, M. R., Fortina, C. A., Mercer, D. F., Vargas, L. M., Grant, W. J., Langnas, A. N. & Merani, S., Nov 1 2019 -
Quality of follow-up: Systematic review of the research in bariatric surgery
Switzer, N. J., Merani, S., Skubleny, D., Pelletier, J. S., Kanji, R., Shi, X., Birch, D. W., De Gara, C., Sharma, A. M., Gill, R. S. & Karmali, S., 2016 -
Repeated metastasectomy in an adolescent with fibrolamellar hepatocellular carcinoma: A case report
Merani, S. & Lees, G. M., May 2016 -
Total pancreatectomy and autoislet transplant for chronic recurrent pancreatitis in a 5-year-old boy
Merani, S., Razzak, R., Kin, T., Haqq, A., Huynh, H. & Shapiro, A. M. J., Oct 1 2016 -
A prevascularized subcutaneous device-less site for islet and cellular transplantation
Pepper, A. R., Gala-Lopez, B., Pawlick, R., Merani, S., Kin, T. & Shapiro, A. M. J., May 12 2015 -
Perioperative factors predicting poor outcome in elderly patients following emergency general surgery: A multivariate regression analysis
Lees, M. C., Merani, S., Tauh, K. & Khadaroo, R. G., Oct 1 2015 -
Predictors of in-hospital mortality and complications in very elderly patients undergoing emergency surgery
Merani, S., Payne, J., Padwal, R. S., Hudson, D., Widder, S. L., Khadaroo, R. G., Brisebois, R., Buttenschoen, K., Fathimani, K., Hamilton, S. M., Lees, G. M., McMullen, T. P. W., Patton, W., Wijngaarden-Stephens, M. V., Sutherland, J. D. & Williams, D. C., Jul 7 2014 -
Research productivity of residents and surgeons with formal research training
Merani, S., Switzer, N., Kayssi, A., Blitz, M., Ahmed, N. & Shapiro, A. M. J., Nov 1 2014 -
A score predicting survival after liver retransplantation for hepatitis C virus cirrhosis
Andres, A., Gerstel, E., Combescure, C., Asthana, S., Merani, S., Majno, P., Berney, T., Morel, P., Kneteman, N., Mentha, G. & Toso, C., Apr 15 2012 -
Characterization of the transcriptome in isolated and transplanted mouse pancreatic islets: Associations with engraftment and dysfunction
Merani, S., Famulski, K. S., Ramassar, V., James Shapiro, A. M. & Halloran, P. F., Mar 2012 -
AEB071 (sotrastaurin) does not exhibit toxic effects on human islets in vitro nor after transplantation into immunodeficient mice
Merani, S., McCall, M., Pawlick, R. L., Edgar, R. L., Davis, J., Toso, C., Emamaullee, J. A., Kin, T. & Shapiro, A. M. J., Nov 2011 -
Bariatric surgery in serious mental illness
Merani, S., Gill, R. S., Sharma, A. M., Birch, D. W. & Karmali, S., Oct 2011 -
The impact of waiting list alpha-fetoprotein changes on the outcome of liver transplant for hepatocellular carcinoma
Merani, S., Majno, P., Kneteman, N. M., Berney, T., Morel, P., Mentha, G. & Toso, C., Oct 2011 -
Caspase inhibitor therapy synergizes with costimulation blockade to promote indefinite islet allograft survival
Emamaullee, J. A., Davis, J., Pawlick, R., Toso, C., Merani, S., Cai, S. X., Tseng, B. & Shapiro, A. M. J., Jun 2010 -
Increasing tuition fees in a country with two different models of medical education
Merani, S., Abdulla, S., Kwong, J. C., Rosella, L., Streiner, D. L., Johnson, I. L. & Dhalla, I. A., Jun 2010 -
Liraglutide, a long-acting human glucagon-like peptide 1 analogue, improves human islet survival in culture
Toso, C., McCall, M., Emamaullee, J., Merani, S., Davis, J., Edgar, R., Pawlick, R., Kin, T., Knudsen, L. B. & Shapiro, A. J., Mar 2010 -
Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellular carcinoma
Toso, C., Merani, S., Bigam, D. L., Shapiro, A. M. J. & Kneteman, N. M., Apr 2010 -
AEB-071 has minimal impact on onset of autoimmune diabetes in NOD mice
Merani, S., Edgar, R. L., Toso, C., Emamaullee, J., Thiesen, A. & Shapiro, A. M. J., 2009 -
BTLA targeting modulates lymphocyte phenotype, function, and numbers and attenuates disease in nonobese diabetic mice
Truong, W., Hancock, W. W., Plester, J. C., Merani, S., Rayner, D. C., Thangavelu, G., Murphy, K. M., Anderson, C. C. & Shapiro, A. M. J., Jul 1 2009 -
Costimulatory blockade with belatacept in clinical and experimental transplantation - A review
Emamaullee, J., Toso, C., Merani, S. & Shapiro, A. M. J., Jun 2009 -
Effect of different induction strategies on effector, regulatory and memory lymphocyte sub-populations in clinical islet transplantation
Toso, C., Edgar, R., Pawlick, R., Emamaullee, J., Merani, S., Dinyari, P., Mueller, T. F., Shapiro, A. M. J. & Anderson, C. C., Feb 2009 -
Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice
Emamaullee, J. A., Davis, J., Merani, S., Toso, C., Elliott, J. F., Thiesen, A. & Shapiro, A. M. J., Jun 2009 -
Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide
Emamaullee, J. A., Merani, S., Toso, C., Kin, T., Al-Saif, F., Truong, W., Pawlick, R., Davis, J., Edgar, R., Lock, J., Bonner-Weir, S., Knudsen, L. B. & Shapiro, A. M. J., May 2009 -
Protein kinase C inhibitor, AEB-071, acts complementarily with cyclosporine to prevent islet rejection in rats
Merani, S., Pawlick, R. L., Edgar, R. L., Toso, C., Emamaullee, J., Anderson, C. C. & Shapiro, A. M. J., Jan 15 2009 -
Sotrastaurin. Protein kinase C inhibitor treatment of transplant rejection treatment of psoriasis treatment of uveitis
McCall, M., Merani, S., Toso, C. & Shapiro, A. M. J., Aug 2009 -
Belatacept and basiliximab diminish human antiporcine xenoreactivity and synergize to inhibit alloimmunity
Emamaullee, J. A., Merani, S., Larsen, C. P. & Shapiro, A. M. J., Jan 2008 -
Combined coinhibitory and costimulatory modulation with anti-BTLA and CTLA4Ig facilitates tolerance in murine islet allografts (American Journal of Transplantation (2007) 7, 12, (2663-2674) DOI: 10.1111/j.1600-6143.2007.01996.x)
Truong, W., Plester, J. C., Hancock, W. W., Merani, S., Murphy, T. L., Murphy, K. M., Kaye, J., Anderson, C. C. & Shapiro, A. M. J., Feb 2008 -
Liraglutide, a long-acting human glucagon-like peptide 1 analog, improves glucose homeostasis in marginal mass islet transplantation in mice
Merani, S., Truong, W., Emamaullee, J. A., Toso, C., Knudsen, L. B. & Shapiro, A. M. J., Sep 2008 -
Optimal implantation site for pancreatic islet transplantation
Merani, S., Toso, C., Emamaullee, J. & Shapiro, A. M. J., Dec 2008 -
The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice
Emamaullee, J. A., Davis, J., Pawlick, R., Toso, C., Merani, S., Cai, S. X., Tseng, B. & Shapiro, A. M. J., Jun 2008 -
The role of macrophage migration inhibitory factor in mouse islet transplantation
Toso, C., Serre-Beinier, V., Emamaullee, J., Merani, S., Armanet, M., Wojtusciszyn, A., Bosco, D., Calandra, T., Roger, T., Morel, P., Shapiro, A. M. J. & Berney, T., Nov 27 2008 -
The role of macrophage migration inhibitory factor on glucose metabolism and diabetes
Toso, C., Emamaullee, J. A., Merani, S. & Shapiro, A. M. J., Nov 2008 -
Combined coinhibitory and costimulatory modulation with anti-BTLA and CTLA4Ig facilitates tolerance in murine islet allografts
Truong, W., Plester, J. C., Hancock, W. W., Merani, S., Murphy, T. L., Murphy, K. M., Kaye, J., Anderson, C. C. & Shapiro, A. M. J., Dec 2007 -
Human islet function is not impaired by the sphingosine-1-phosphate receptor modulator FTY720
Truong, W., Emamaullee, J. A., Merani, S., Anderson, C. C. & James Shapiro, A. M., Aug 2007 -
Negative and positive co-signaling with anti-BTLA (PJ196) and CTLA4Ig prolongs islet allograft survival
Truong, W., Plester, J. C., Hancock, W. W., Kaye, J., Merani, S., Murphy, K. M., Murphy, T. L., Anderson, C. C. & Shapiro, A. M. J., Nov 2007 -
Chemokines and their receptors in islet allograft rejection and as targets for tolerance induction
Merani, S., Truong, W. W., Hancock, W., Anderson, C. C. & Shapiro, A. M. J., 2006 -
Coinhibitory T-cell signaling in islet allograft rejection and tolerance
Truong, W., Hancock, W. W., Anderson, C. C., Merani, S. & Shapiro, A. M. J., 2006 -
Compaction of islets is detrimental to transplant outcome in mice
Merani, S., Schur, C., Truong, W., Knutzen, V. K., Lakey, J. R. T., Anderson, C. C., Ricordi, C. & Shapiro, A. M. J., Dec 2006 -
Current status of pancreatic islet transplantation
Merani, S. & Shapiro, A. M. J., Jun 2006 -
Frontline: Inhibition of allergen-induced pulmonary inflammation by the tripeptide feG: A mimetic of a neuro-endocrine pathway
Dery, R. E., Ulanova, M., Puttagunta, L., Stenton, G. R., James, D., Merani, S., Mathison, R., Davison, J. & Befus, A. D., Dec 2004 -
Inhibition of allergic inflammation in the airways using aerosolized antisense to Syk kinase
Stenton, G. R., Ulanova, M., Déry, R. E., Merani, S., Kim, M. K., Gilchrist, M., Puttagunta, L., Musat-Marcu, S., James, D., Schreiber, A. D. & Befus, A. D., Jul 15 2002