Peter J. Giannini, DDS, MS

Dr. Giannini

Associate Professor

Director, Clinical and Translational Research
Cruzan Center for Dental Research
Department of Oral Biology
University Dental Associates, Biopsy Service

Contact Information

Room 1463, UNMC College of Dentistry
4000 East Campus Loop South
Lincoln, NE 68583-0740


Teaching Responsibilities 
  • Course Director - General Pathology I (ORBI 539), Integrated General and Oral Pathology for the Dental Hygienist (ORBI 366)
  • Course Instructor - A Review of Biomedical/Dental Sciences (ORBI 471), Clinical Oral Pathology (ORBI 491), General Pathology II (ORBI 540), Oral Medicine (ORBI 648), Oral Pathology (ORBI 566)
  • Module Coordinator, Clinical Oral Pathology (CCC 4)
Research Interests 
  • Management of oral mucosal disease
  • Oral carcinogenesis and cytoprotective enzymes
  • Oral manifestations of drug abuse
Selected Publications 
  • Rector J, Kapil S, Treude KJ, Kumm P, Glanzer JG, Byrne BM, Liu S, Smith LM, DiMaio DJ, Giannini P, Smith RB, and Oakley GG. S4S8-RPA Phosphorylation as an Indicator of Cancer Progression in Oral Squamous Cell Carcinomas. Oncotarget 8(6):9243-50. 2017.
  • Badger, GR, Fryer CES, Giannini PJ, Townsend JA, and Huja S. Helping dental students make informed decisions about private practice employment options in a changing landscape. J of Dental Educ 79(12):1396-1401, 2015.
  • Knudsen M, Bury M, Holwegner C, Reinhardt AL, Yuan, F, Zhang Y, Giannini P, Marx DB, Wang D, and Reinhardt RA. Effect of dexamethasone prodrug on inflamed TMJs in juvenile rats. Arthritis Res & Therapy 17:267, 2015.
  • Untrauer JB, Giannini PJ, Talmon GA, and Johansson SL. Malignant PEComa involving the mandible: Report of a unique case. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology 117(1):e3-e8, January 2014.
  • Wang L, Luong VQ, Giannini PJ, and Peng A. Mastl kinase, a promising therapeutic target, promotes cancer recurrence. Oncotarget 5(22):11479-89, November 30, 2014.
  • George MD, Owen CM, Reinhardt AL, Giannini PJ, Marx DB, and Reinhardt RA. Effect of Simvastatin injections on temporomandibular joint inflammation in growing rats. J of Oral and Maxillofacial Surgery 71(5):846-853, 2013.
  • Gonzalez, S.M., Spalding, P.M., Payne, J.B., and Giannini, P.J.  A dentigerous cyst associated with bilaterally impacted mandibular canines in a girl: A case report. Journal of Medical Case Reports 5:230, 2011.
  • Giannini, P.J. and Shetty, K.V.  Diagnosis and Management of oral candidiasis. Otolaryngologic Clinics of North America 44:231-40, 2011.
  • Rutledge, J., Schieber, MD, Chamberlain, J.M., Byarlay, M., Killeen, A.C., Giannini, P.J., Marx, D.B., and Reinhardt, R.A. Simvastatin application to augment facial jaw bone in a dog model: Pilot study. Journal of Periodontology 82(4):597-605, April 2011.
  • Fung, E.Y.K. and Giannini, P.J. Implications of drug dependence on dental patient management. General Dentistry 236-241, May/June 2010.
  • Narayana, N., Gifford, R., Giannini, P.J., and Casey, J.H. Oral histoplasmosis: An unusual presentation: A case report. Head Neck 31(2):274-7, February, 2009.
  • Morris, MS, Lavin, MT, Giannini, P.J., Schmid, M.J., Marx, D.B., and Reinhardt, R.A. Injectable simvastatin in periodontal defects and alveolar ridges in dogs. J Periodontology 79(8):1465-73, August 2008.
  • Giannini, P.J., Gross, H.B., Strong, B.M., and Litchmore, L.A. Differential diagnosis of periapical radiolucencies and case presentation. Inside Dentistry 4(7):38-44, July/August 2008.
  • Giannini, P.J., Morse, M.A., Weghorst, C.M., Pei, P. and Mallery, S.R. Functional activities and immunohistochemical cellular distribution of glutathione S-transferases in normal, dysplastic, and squamous cell carcinoma human oral tissues. Clinical Medicine Oncology 2:159-68, 2008.
  • Gross, H.B., Giannini, P.J., Lantzy, L.A., Gordon, S.C. and Reid, W.D. Oral pathology quiz #17: Incidental red and white lesion. J of the Michigan Dental Association 88(6):34, 52-3, June 2006.
  • Shetty, K.V., Giannini, P.J. and Springstead, M.C. What the dental hygienist should know about prion disease. Contemporary Oral Hygiene 6(3):29-33, March 2006.
  • Shetty, K.V., Giannini, P.J. and Achong, R. Chronic craniofacial dematiaceous fungal infection: A case report. Special Care Dentistry 26(4):155-58, 2006.
  • Giannini, P.J., Shetty, K.V., Horan, S.L., Reid, W.D. and Litchmore, L.A. Adenoid cystic carcinoma of the buccal vestibule: A case report and review of the literature. Oral Oncology 42(10):1029-1032, 2006.
  • Shetty, K.V., Vastardis, S. and Giannini, P.J. Management of an unusually large adenomatoid odontogenic tumor. Oral Oncology EXTRA 41(10):316-18, November 2005.
  • Shetty, K.V., Giannini, P.J., and Achong, R. Kaposi's sarcoma of lymph node leading to a diagnosis of HIV. Oral Oncology EXTRA 41(9):234-37, October 2005.
  • Devlin, H. and Giannini, P.J. Financing student education in the future. British Dental Journal 199:561-63, January 2005.
  • Mohammad, A.R. and Giannini, P.J. Oral candidiasis: Current concepts in the diagnosis and management in the institutionalized elderly patient. A review. Dental Forum 33(2):65-70, 2005.
  • Shetty, K.V., Giannini, P.J. and Leigh, J. E. A hybrid giant cell granuloma and fibro-osseous lesion of the mandible. Oral Oncology EXTRA 40(7):81-84, August 2004.
  • Mohammad, A.R., Giannini, P.J., Preshaw, P.M. and Alliger, H. Clinical and microbiological efficacy of chlorine dioxide (CIO2) in the management of chronic atrophic candidiasis. International Dental Journal 54(3):154-58, June 2004.
  • Bassiouny, M.A., Giannini, P.J. and Deem, L.P. Permanent incisors traumatized through predecessors: Sequelae and possible management. J of Clinical Pediatric Dentistry 27(3):223-28, 2003.
Selected Book Chapters 
  • Alonzo, T.A. and Giannini, P.J. Assessing Accuracy of Oral Health Diagnostic Tests. Statistical and Methodological Aspects of Oral Health Research, Lesaffre E, Feine J, Leroux B, Declerck D (eds.), pp. 205-218. Hoboken, NJ, John Wiley & Sons, Ltd., 2009. 
Selected Abstracts 
  • Knudsen M, Bury M, Giannini PJ, Holwegner CO, Marx DB, Wang D, and Reinhardt RA. Temporomandibular joint inflammation and mandibular development in growing rats. Presented at the International Association of Dental Research Meeting in Boston, Massachusetts, March 2015. 
  • Giannini PJ, Narayana N, Casey JH, and Jenkins M. Spindle cell carcinoma of the oral cavity in a patient with no prior history of radiation therapy to the head and neck: Unusual presentation. Presented at the 5th World Congress of the International Academy of Oral Oncology in Sao Paulo, Brazil, July 2015.
  • Giannini, P.J., Narayana, N., Casey, J.H., and Kugler, S. Malignant transformation associated with the use of smokeless tobacco. Presented at the 17th International Congress on Oral Pathology and Medicine, Istanbul, Turkey, May 2014.
  • Giannini, .PJ., Narayana, N., Casey, J.H., and Henriksen, B.J.  Metastatic adenocarcinoma of the breast presenting as a periapical abscess.  Oral Surgery, Oral Medicine, Oral Pathology, and Oral Radiology 114(4):e98, October 2012. Presented at the 16th International Congress on Oral Pathology and Medicine and 20thBrazilian Congress on Oral Pathology and Medicine Meeting in Sao Pedro, SP, Brazil, August 2012. 
  • Giannini, P.J. and Mack, E.L.  Adenocarcinoma of the lung initially presenting as a gingival metastasis.  Presented at the American Academy of Oral Medicine Meeting in Charleston, South Carolina, April 2012.
  • Giannini, P.J. and Glenn, A.R.  Clear cell odontogenic carcinoma of the mandible. Presented at the American Academy of Oral Medicine Meeting in Carolina, Puerto Rico, April 2011.
  • Giannini, P.J., Haralson, D.J., and Johansson, S.L.  Osteosarcoma of the maxilla secondary to radiation treatment.  Presented at the American Academy of Oral Medicine Meeting in Santa Ana Pueblo, New Mexico, April 2010.
  • Miller, A.R., Walke,r A., Fung, E., and Giannini, P.J. The influence of substance abuse on oral health.  Presented at the International Association of Dental Research Meeting in Miami Beach, Florida, April 2009.  
  • Giannini, P.J., Shetty, K.V., Narayana, N. and Zysset, M.K. Spontaneous necrosis of a pleomorphic adenoma of the palate: An unusual case. 19th Congress of the International Association for Disability and Oral Health Meeting in Santos, Brazil, October 2008.
  • Chamberlain, J.M., Schieber, MD, Byarlay, M.R., Giannini, P.J. Killeen, A.C., Marx, D.B. and Reinhardt, R.A. Effects of simvastatin on guided bone regeneration. International Association of Dental Research Meeting, Toronto, Ontario, July 2008.
  • Giannini, P.J., Shetty K.V., Narayana, N., Blaha, D.A. and Greiner, T.C. Plasmablastic lymphoma of the oral cavity in an HIV-negative patient: An unusual case report. American Academy of Oral Medicine Meeting in Scottsdale, Arizona, April 2008.
  • Shetty, K.V. and Giannini, P.J. Saliva as a diagnostic tool. Greater New York Dental Meeting, New York, New York, November 2007.
  • Narayana, N., Giannini, P.J. and Casey, J.H. Atypical oral lesion in a patient on Infliximab: A case report. American Academy of Oral and Maxillofacial Pathology Meeting, Kansas City, Missouri, May 2007.