University of Nebraska Medical Center
University of Nebraska Medical Center

Marburg Virus Disease

 

Green microscopic marburg viruses on a red background.

About Marburg 

Marburg Virus Disease (MVD) is a severe, often fatal viral hemorrhagic fever caused by Marburg virus, a member of the Filoviridae family (the same family as Ebola). It is characterized by sudden onset, rapid clinical deterioration, and multi-organ involvement, with high mortality if not managed promptly.

Currently, there are no Food and Drug Administration (FDA)-approved vaccines or treatments for MVD. In the absence of early diagnosis and appropriate supportive care, the mortality rate for MVD ranges from 23% to 90%. With prompt intensive supportive care and fluid replacement, it is possible to achieve lower mortality rates.