University of Nebraska Medical Center

Dr. Santarpia's Publications




  1. Santarpia, J.L., Li, R. J., & Collins, D.R. (2004). Direct measurement of the hydration state of ambient aerosol populations.  Journal of Geophysical Research-Atmospheres, 109(D18), 16.  doi:10.1029/2004jd004653
  2. Santarpia, J. L., Gasparini, R., Li, R. J., & Collins, D. R. (2005). Diurnal variations in the hygroscopic growth cycles of ambient aerosol populations. Journal of Geophysical Research-Atmospheres, 110(D3), 12. doi:10.1029/2004jd005279
  3. Kaku, K. C., Hegg, D. A., Covert, D. S., Santarpia, J. L., Jonsson, H., Buzorius, G., & Collins, D. R. (2006). Organics in the Northeastern Pacific and their impacts on aerosol hygroscopicity in the subsaturated and supersaturated regimes. Atmospheric Chemistry and Physics, 6, 4101-4115. doi:10.5194/acp-6-4101-2006
  4. Ratnesar-Shumate, S., Wagner, M. L., Kerechanin, C., House, G., Brinkley, K. M., Bare, C., . . . Santarpia, J. L. (2011). Improved Method for the Evaluation of Real-Time Biological Aerosol Detection Technologies. Aerosol Science and Technology, 45(5), 635-644. doi:10.1080/02786826.2010.551144
  5. Santarpia, L., Collins, D. R., Hegg, D. A., Kaku, K. C., Covert, D. S., Jonsson, H., & Buzorius, G. (2011). Estimates of aqueous-phase sulfate production from tandem differential mobility analysis. Atmospheric Environment, 45(31), 5484-5492. doi:10.1016/j.atmosenv.2011.06.05
  6. Santarpia, J.L., Pan, Y.L., Hill, S.C., Baker, N., Cottrell, B., McKee, L,. . . . Pinnick, R.G. (2012). Changes in fluorescence spectra of bioaerosols exposed to ozone in a laboratory reaction chamber to simulate atmospheric aging.  Optics Express, 20(28), 29867-29881.   doi:10.1364/oe.20.029867
  7. Hill, S. C., Pan, Y. L., Williamson, C., Santarpia, J. L., & Hill, H. H. (2013). Fluorescence of bioaerosols: mathematical model including primary fluorescing and absorbing molecules in bacteria. Optics Express, 21(19), 22285-22313. doi:10.1364/oe.21.022285
  8. Santarpia, J. L., Ratnesar-Shumate, S., Gilberry, J. U., & Quizon, J. J. (2013). Relationship Between Biologically Fluorescent Aerosol and Local Meteorological Conditions. Aerosol Science and Technology, 47(6), 655-661. doi:10.1080/02786826.2013.781263
  9. Hill, S. C., Doughty, D. C., Pan, Y. L., Williamson, C., Santarpia, J. L., & Hill, H. H. (2014). Fluorescence of bioaerosols: mathematical model including primary fluorescing and absorbing molecules in bacteria: errata. Optics Express, 22(19), 22817-22819. doi:10.1364/oe.22.022817
  10. Pan, Y. L., Hill, S. C., Santarpia, J. L., Brinkley, K., Sickler, T., Coleman, M., . . . Gardner, W. (2014). Spectrally-resolved fluorescence cross sections of aerosolized biological live agents and simulants using five excitation wavelengths in a BSL-3 laboratory. Optics Express, 22(7), 8165-8189. doi:10.1364/oe.22.008165
  11. Pan, Y. L., Santarpia, J. L., Ratnesar-Shumate, S., Corson, E., Eshbaugh, J., Hill, S. C., . . . Kinahan, S. (2014). Effects of ozone and relative humidity on fluorescence spectra of octapeptide bioaerosols particles. Journal of Quantitative Spectroscopy & Radiative Transfer, 133, 538-550. doi:10.1016/j.jqsrt.2013.09.017
  12. Pan, Y. L., Wang, C. J., Hill, S. C., Coleman, M., Beresnev, L. A., & Santarpia, J. L. (2014). Trapping of individual airborne absorbing particles using a counterflow nozzle and photophoretic trap for continuous sampling and analysis. Applied Physics Letters, 104(11), 4. doi:10.1063/1.4869105
  13. Hill, S. C., Williamson, C. C., Doughty, D. C., Pan, Y. L., Santarpia, J. L., & Hill, H. H. (2015). Size-dependent fluorescence of bioaerosols: Mathematical model using fluorescing and absorbing molecules in bacteria. Journal of Quantitative Spectroscopy & Radiative Transfer, 157, 54-70. doi:10.1016/j.jqsrt.2015.01.011
  14. Ratnesar-Shumate, S., Pan, Y. L., Hill, S. C., Kinahan, S., Corson, E., Eshbaugh, J., & Santarpia, J. L. (2015). Fluorescence spectra and biological activity of aerosolized bacillus spores and MS2 bacteriophage exposed to ozone at different relative humidities in a rotating drum. Journal of Quantitative Spectroscopy & Radiative Transfer, 153, 13-28. doi:10.1016/j.jqsrt.2014.10.003
  15. Lai, C. W., Schwab, M., Hill, S. C., Santarpia, J., & Pan, Y. L. (2016). Raman scattering and red fluorescence in the photochemical transformation of dry tryptophan particles. Optics Express, 24(11), 1654-1667. doi:10.1364/oe.24.011654
  16. Fu, R., Wang, C. J., Munoz, O., Videen, G., Santarpia, J. L., & Pan, Y. L. (2017). Elastic back-scattering patterns via particle surface roughness and orientation from single trapped airborne aerosol particles. Journal of Quantitative Spectroscopy & Radiative Transfer, 187, 224-231. doi:10.1016/j.jqsrt.2016.09.018
  17. Kalume, A., Beresnev, L. A., Santarpia, J., & Pan, Y. L. (2017). Detection and characterization of chemical aerosol using laser-trapping single-particle Raman spectroscopy. Applied Optics, 56(23), 6577-6582. doi:10.1364/ao.56.006577
  18. Kalume, A., Zhu, E., Wang, C. J., Santarpia, J., & Pan, Y. L. (2017). Position-resolved Raman spectra from a laser-trapped single airborne chemical droplet. Optics Letters, 42(24), 5113-5116. doi:10.1364/ol.42.005113
  19. Pan, Y.L., Wang, C. J., Beresnev, L. A., Yufa, A. J., Videen, G., Ligon, D., & Santarpia, J. L. (2017). Measurement of back-scattering patterns from single laser trapped aerosol particles in air. Applied Optics, 56(3), B1-B4. doi:10.1364/ao.56.0000b1
  20. Pan, Y.L., Kalume, A., Wang, C., Santarpia, J. L. (2018). Optoaerodynamic focusing of aerosol particles. Aerosol Science and Technology, 52(1), 13-18.
  21. Kalume, A., Gong, Z., Wang, C., Santarpia, J.L., Pan, Y.L. (Jan 1, 2018). Detection and characterization of chemical and biological aerosols using laser-trapping single-particle Raman spectroscopy.  WIT Transactions on Ecology and the Environment. 230, p. 323-329.
  22. Kalume, A., Wang, C. Santarpia J.L., Pan Y.L., (Jan 1, 2018). Liquid-liquid phase separation and evaporation of a laser-trapped organic-organic airborne droplet using temporal spatial-resolved Raman spectroscopy.  Physical Chemistry Chemical Physics. 20, 28, p. 19151-19159
  23. Kalume, A., Wang C., Santarpia, J.L., Pan, Y.L.. (Aug 16, 2018).  Study of single airborne particle using laser-trapped submicron position-resolved temporal Raman spectroscopy.  Chemical Physics Letters.  706, P. 255-260.
  24. Gibbs, S.G., Herstein, J.J., Le, A.B., Beam, E.L., Cieslak, T.J., Lawler, J.V., Santarpia, J.L., Stentz, T.L., Kopocis-Herstein, K.R., Achutan, C., Carter, G.W.; Lowe, J-M. J. (May 1 2019) Need for Aeromedical Evacuation High-Level Containment Transport Guidelines. Emerging infectious diseases. 25, 5, p. 1033-1034.  PMID #30741629
  25. Kinahan, S.M., Tezak, M.S.,  Siegrist, C.M., Lucero, G., Servantes, B.L.,  Santarpia, J.L., Kalume, A., Zhang, J., Felton, M., Hill, S.C., Williamson, C.C., Pan, Y.L.. (2019). Changes of fluorescence spectra and viability from aging aerosolized coli cells under various laboratory-controlled conditions in an advanced rotating drum. Aerosol Science and Technology, 53:11, 1261-1276, DOI: 10.1080/02786826.2019.1653446.
  26. Santarpia, J.L., Ratnesar-Shumate, S., Haddrell, A. (2020). Laboratory Study of Bioaerosols: Traditional Test Systems, Modern Approaches, and Environmental Control. Aerosol Science and Technology. 54 (5), 585-600.
  27. Pan Y-L., Kalume A., Lenton I.C.D., Nieminen T.A., Stilgoe A.B., Rubinsztein-Dunlop H., Beresnev L.A., Wang C., Santarpia J.L. (2019). Optical-trapping of particles in air using parabolic reflectors and a hollow laser beam.  Express 27, 33061-33069.
  28. Gibbs, S.G., Herstein, J.J.,  Le, A.B.,  Beam, E.L.,  Cieslak, T.J.,  Lawler, J.V., Santarpia, J.L., Stentz, T.L.,  Kopocis-Herstein, K.R.,  Achutan, C.,  Carter, G.W.,  Lowe, J.J (2019). Review of literature for air medical evacuation high-level containment transport. Air medical journal, 38(5), 359-365.
  29. Santarpia, J.L., Rivera, D.N., Herrera, V.L. et al. Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care. Sci Rep 10, 12732 (2020). https://doi.org/10.1038/s41598-020-69286-3
  30. Siegrist, C.M., Kinahan, S.M., Settecerri, T., Greene, A.C. & Santarpia, J.L. (2020). CRISPR/Cas9 as an antiviral against Orthopoxviruses using an AAV vector. Sci Rep 10, 19307 (2020). https://doi.org/10.1038/s41598-020-76449-9
  31. Pan, Y. L., Kalume, A., Kinahan, S., Tezak, M., & Santarpia, J. (2020). Bioaerosol property and viability affected by various environmental factors. International Journal of Environmental Impacts, 3(1), 19-30.
  32. Hubbard, J.A., Boyle, T.J., Zepper, E.T., Brown, A., Settecerri, T., Santarpia, J.L., Kotula, P., McKenzie, B., Lucero, G.A., Lemieux, L.J. and Zigmond, J.A. (2021). Airborne Release Fractions from Surrogate Nuclear Waste Fires Containing Lanthanide Nitrates and Depleted Uranium Nitrate in 30% Tributyl Phosphate in Kerosene. Nuclear Technology, 207(1), pp.103-118. doi:10.1080/002955450.2020.1739995
  33. McCarthy, A., Saldana, L., Ackerman, D.N., Su, Y., John, J.V., Chen, S., Weihs, S., Reid, S.P., Santarpia, J.L., Carlson, M.A. and Xie, J., 2021. Ultra-absorptive Nanofiber Swabs for Improved Collection and Test Sensitivity of SARS-CoV-2 and other Biological Specimens. Nano Letters, 21(3), pp.1508-1516.
  34. Hubbard, J.A., Boyle, T.J., Zepper, E.T., Brown, A., Settecerri, T., Santarpia, J.L., Bell, N., Zigmond, J.A., Storch, S.S., Maes, B.J. and Zayas, N.D., 2021. Determination of Airborne Release Fractions from Solid Surrogate Nuclear Waste Fires. Nuclear Technology, pp.1-17.
  35. Pan, Y. L., Kalume, A., Wang, C., & Santarpia, J. (2021). Atmospheric aging processes of bioaerosols under laboratory-controlled conditions: A review. Journal of Aerosol Science, 155, 105767.
  36. Santarpia, J. L., Herrera, V. L., Rivera, D. N., Ratnesar-Shumate, S., Reid, S. P., Ackerman, D. N., ... & Lowe, J. J. (2021). The size and culturability of patient-generated SARS-CoV-2 aerosol. Journal of exposure science & environmental epidemiology, 1-6.
  37. Barksdale, A. N., Zeger, W. G., Santarpia, J. L., Herrera, V. L., Ackerman, D. N., Lowe, J. J., & Wadman, M. C. (2021). Implementation of a COVID-19 cohort area resulted in no surface or air contamination in surrounding areas in one academic emergency department. The American Journal of Emergency Medicine, 47, 253-257.
  38. Sirmollo, C. L., Collins, D. R., McCormick, J. M., Milan, C. F., Erickson, M. H., Flynn, J. H., ... & Santarpia, J. L. (2021). Captive Aerosol Growth and Evolution (CAGE) chamber system to investigate particle growth due to secondary aerosol formation. Atmospheric Measurement Techniques, 14(5), 3351-3370.
  39. Crowe, A. T. Schnaubelt, S. Schmidt-Bonne, K. Angell, J. Bai, T. Eske, M. Nicklin, C. Pratt, B. White, B. Crotts-Hannibal, N. Staffend, V. Herrera, J. Cobb, J. Conner, J. Carstens, J. Tempero, L. Bouda, M. Ray, J. V. Lawler, W. S. Campbell, J.-M. Lowe, J. L. Santarpia, S. Bartelt-Hunt, M. Wiley, D. Brett-Major, C. Logan, M. J. Broadhurst. (2021). Assessment of a program for SARS-CoV-2 screening and environmental monitoring in an urban public school district. JAMA network open, 4(9), e2126447-e2126447.
  40. Kinahan, S. M., Silcott, D. B., Silcott, B. E., Silcott, R. M., Silcott, P. J., Silcott, B. J., ... & Santarpia, J. L. (2021). Aerosol tracer testing in Boeing 767 and 777 aircraft to simulate exposure potential of infectious aerosol such as SARS-CoV-2. PloS one, 16(12), e0246916.
  41. Lowe, A. E., Dineen, K. K., Herstein, J. J., Wynia, M. K., Santarpia, J. L., Lee, L. M., ... & Mohapatra, S. (2021). Emerging science, personal protective equipment guidance, and resource scarcity: Inaction and inequity for workers in essential industries. Health security, 19(5), 564-569.
  42. Ratnesar-Shumate, S., & Santarpia, J. (2021). Aerosol Science and the Dynamics of Airborne Transmission. Journal of Dental Infection Control and Safety, 3, 28941.
  43. Pan, Y. L., Aptowicz, K., Arnold, J., Cheng, S., Kalume, A., Piedra, P., Wang, C., Santarpia, J.L., & Videen, G. (2022). Review of elastic light scattering from single aerosol particles and application in bioaerosol detection. Journal of Quantitative Spectroscopy and Radiative Transfer, 108067.
  44. Pan, Y. L., Kalume, A., Arnold, J., Beresnev, L., Wang, C., Rivera, D. N., ... & Santarpia, J. (2022). Measurement of circular intensity differential scattering (CIDS) from single airborne aerosol particles for bioaerosol detection and identification. Optics Express, 30(2), 1442-1451.
  45. John, J. V., McCarthy, A., Su, Y., Ackerman, D. N., Shahriar, S. S., Carlson, M. A., Reid, S.P., Santarpia, J.L., Zhu, W., & Xie, J. (2022). Nanofiber capsules for minimally invasive sampling of biological specimens from gastrointestinal tract. Acta Biomaterialia.
  46. Trent, S., Davis, A., Wu, T., Menard, D., Cummins, J.J., Santarpia, J.L., Olson, N. (2022). Inhaled Mass and Particle Removal Dynamics in Commercial Buildings and Aircraft Cabins. ASHRAE Journal, 64 (7).
  47. Mayes, C. M., & Santarpia, J. (2022). Evaluating the Impact of gRNA SNPs in CasRx Activity for Reducing Viral RNA in HCoV-OC43. Cells, 11(12), 1859.
  48. Santarpia, J.L.; Markin, N.W.; Herrera, V.L.; Ackerman, D.N.; Rivera, D.N.; Lucero, G.A.; Lisco, S.J. Infectious Aerosol Capture Mask as Environmental Control to Reduce Spread of Respiratory Viral Particles. Viruses 2022, 14, 1275. https://doi.org/10.3390/v14061275
  49. Santarpia, J.L., Collins, D.R., Ratnesar-Shumate, S.A., Glen, C.C., Sanchez, A.L., Antionetti, C.G., Taylor, J., Taylor, N.F., Bare, C.A., Kinahan, S.M., Rivera, D.N., Corson, E., Hill, S.C., Williamson, C.C., Coleman, M., Pan, Y.L. (2022). Changes in the Fluorescence of Biological Particles Exposed to Environmental Conditions in the National Capitol Region. Atmospheres, 2022, 13(9), 1358; https://doi.org/10.3390/atmos13091358
  50. Stein, S.J.; Ravnholdt, A.R.; Herrera, V.L.; Rivera, D.N.; Williams, P.T.; Santarpia, J.L. SARS-CoV-2 Aerosol and Surface Detections in COVID-19 Testing Centers and Implications for Transmission Risk in Public Facing Workers.  J. Environ. Res. Public Health202320, 976. https://doi.org/10.3390/ijerph20020976.
  51. Xu, Y., Su, Y., Xu, X., Arends, B., Zhao, G., Ackerman, D.N., Huang, H., Reid, S.P., Santarpia, J.L., Kim, C. and Chen, Z., 2023. Porous liquid metal–elastomer composites with high leakage resistance and antimicrobial property for skin-interfaced bioelectronics. Science Advances9(1), https://doi.org/10.1126/sciadv.adf0575
  52. Surkov, Y., Shkuratov, Y., Pan, Y.L., Kalume, A., Santarpia, J., Zubko, E., Hu, Y. and Videen, G., 2023. Light scattering from spiral particles. Journal of Quantitative Spectroscopy and Radiative Transfer, https://doi.org/10.1016/j.jqsrt.2023.108494
  53. Mayes, C.M. and Santarpia, J.L., 2023. Pan-Coronavirus CRISPR-CasRx Effector System Significantly Reduces Viable Titer in HCoV-OC43, HCoV-229E, and SARS-CoV-2. The CRISPR Journal. https://doi.org/10.1089/crispr.2022.0095
  54. Santarpia, J.L., Klug, E., Ravnholdt, A. and Kinahan, S.M., 2023. Environmental sampling for disease surveillance: Recent advances and recommendations for best practice. Journal of the Air & Waste Management Association73(6), pp.434-461. https://doi.org/10.1080/10962247.2023.2197825




  1. Santarpia Aerobiology: The Toxicology of Airborne Pathogens and Toxins. RSC; 2016. Chapter 6, Bioaerosols in the Environment: Populations, Measurement and Processes; 219-247
  2. Huffman JA; Santarpia Microbiology of Aerosols. 1st. Wiley-Blackwell; 2017. Chapter 1.4, Online Techniques for Quantification and Characterization of Biological Aerosols; 83-114
  3. Kalume A; Wang C; Santarpia JL; Pan YL. Clinical and Translational Biophotonics. F91-TRANSL. The Optical Society;TRANSLATIONAL; Submicron position-resolved Raman spectra for characterizing laser-trapped single airborne particles