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University of Nebraska Medical Center

1 in 5 COVID survivors still have symptoms 3 years after severe infection, analysis estimates

CIDRAPmeta-analysis of 11 studies suggests that 20% of patients, most with severe COVID-19, had at least one symptom 3 years after infection, primarily fatigue, sleep disturbances, and shortness of breath.

Researchers in Europe, Asia, and Australia assessed the pooled prevalence of persistent COVID-19 symptoms 3 years after infection in observational studies published in 2023 and 2024. The studies, which reported data from 142,171 long-COVID patients aged 36 to 86 years (87% men), were conducted in Bulgaria, China, Japan, Italy, Romania, and the United States. 

All but one study focused on COVID-19 patients hospitalized in 2020; the other involved non-hospitalized patients. The authors reported the findings late last week in the Journal of Medical Virology.

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