The Missouri Department of Health and Senior Services confirmed two cases of clade I mpox in residents who recently traveled internationally.
Clade I mpox, formerly referred to as “monkeypox,” has been spreading globally since 2024. It is different from the clade II mpox outbreak in 2022.
Clade I mpox is “more likely to cause severe illness and death,” particularly in those who are immunocompromised.
These are the first known cases of clade I mpox in Missouri and the 13th and 14th nationally.
Both individuals had recently traveled to countries where mpox is more prevalent, the health department said. The two cases are reportedly unrelated.
“While risk to the general public remains low, mpox is still active,” said Dr. George Turabelidze, state epidemiologist, in a news release. “We recommend those who are at risk for mpox infection to get vaccinated and ensure they complete the 2-dose series.”
Both clade I and II mpox primarily spread through direct physical contact with a symptomatic person or through contact with used items contaminated with the virus.