Frontiers Background:
Live animal and wet markets (LWM) serve as critical interfaces where humans closely interact with domestic and peri-domestic animals, facilitating the spillover of zoonotic pathogens. Previous outbreaks of avian influenza viruses (AIV) and coronaviruses (CoV) linked to these markets underscore their significant public health risks. Despite the high density of LWM and historical viral spillovers in Southeast Asia, studies on the prevalence of respiratory viruses in LWM in Laos remain limited.