Category: Marburg Virus
Tanzania reports a Marburg outbreak, Africa’s second this year
STAT News Africa is grappling with not one, but two outbreaks of Marburg fever, a disease that causes symptoms and a death rate comparable to Ebola, its viral cousin. Health officials in Tanzania announced Tuesday that they had confirmed the country’s first-ever Marburg outbreak, involving at least eight people so far, five of whom have […]
Mar 21, 2023
Cameroon Situation Update on Marburg
DOWNLOAD Marburg Virus Disease (MVM) Situation Report No. 3 HIGHLIGHTS Machine Translated AREAS OF INTERVENTION 1. MONITORING 1.1 Alert management Alerts come from health facilities (71.4%), calls from the community (21.4%) and investigation teams (7.2%). 1.2 Surveillance at points of entry In total 285 Disembarked, 285 Screened, 285 Sensitized and no suspected cases 2. CONTACT INVESTIGATION […]
Mar 14, 2023
Marburg virus outbreaks are increasing in frequency and geographic spread – three virologists explain
(The Conversation) The World Health Organization confirmed an outbreak of the deadly Marburg virus disease in the central African country of Equatorial Guinea on Feb. 13, 2023. To date, there have been 11 deaths suspected to be caused by the virus, with one case confirmed. Authorities are currently monitoring 48 contacts, four of whom have developed symptoms and […]
Mar 14, 2023
Cameroon – Anticipatory action for Marburg
Relief Web Since February 7, 2023, several suspected cases with symptoms of Marburg Hemorrhagic Fever have been declared in Equatorial Guinea in districts of Kie-Ntem province. On February 13, 2023, the first Marburg epidemic was declared by confirmation of a positive sample. Several contact cases are to be traced and Cameroon has recorded suspect cases […]
Mar 7, 2023
What is Marburg virus and should we be worried?
(The Conversation) An epidemic outbreak of Marburg virus in Equatorial Guinea, Central Africa, was confirmed this week, the first time the virus has occurred there. At least 16 cases have been detected, and nine deaths. There are no approved treatments for Marburg virus, which is closely related to Ebola virus, but vaccines are in development. Following an unprecedented […]
Feb 17, 2023
Marburg virus outbreak: researchers race to test vaccines
(Nature) Control measures such as quarantine could end the outbreak in Equatorial Guinea quickly — good news for inhabitants but a mixed blessing for clinical trials. Health officials worldwide are sprinting to test whether experimental vaccines can protect against a deadly illness, after Equatorial Guinea confirmed its first outbreak of Marburg virus disease on 13 […]
Feb 15, 2023
Cameroon detects two suspected cases of Marburg virus near Eq. Guinea
(Reuters) – Cameroonian authorities detected two suspected cases of Marburg disease on Monday in Olamze, a commune on the border with Equatorial Guinea, the public health delegate for the region, Robert Mathurin Bidjang, said on Tuesday. Equatorial Guinea officially declared its first outbreak of the Marburg virus, an illness similar to Ebola, on Monday. Neighbouring Cameroon had restricted movement along the […]
Feb 14, 2023
Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in-human, phase 1, open-label, dose-escalation trial
(The Lancet) WHO has identified Marburg virus as an emerging virus requiring urgent vaccine research and development, particularly due to its recent emergence in Ghana. We report results from a first-in-human clinical trial evaluating a replication-deficient recombinant chimpanzee adenovirus type 3 (cAd3)-vectored vaccine encoding a wild-type Marburg virus Angola glycoprotein (cAd3-Marburg) in healthy adults.
Feb 14, 2023
Marburg vaccine shows promising results in first-in-human study
(NIH) A newly published paper in The Lancet shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial. The vaccine, developed by researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, could someday be an important tool […]
Feb 14, 2023