Category: Emerging Infectious Diseases
COVID Autopsies Reveal The Virus Spreading Through The ‘Entire Body’
(ScienceAlert) Dozens of recent autopsies show persistent evidence of SARS-CoV-2 throughout the body, including in the lungs, the heart, the spleen, the kidneys, the liver, the colon, the thorax, muscles, nerves, the reproductive tract, the eye, and the brain. Related Study in Nature
Jan 10, 2023
Study Finds There Are 4 Subtypes of Long COVID
(Prevention) Research has found that long COVID impacts one in five adults under the age of 65, but scientists are still trying to learn more about the condition. Now, a new study has found there are actually four main subtypes of long COVID. The study, which was published in the journal Nature Medicine, used machine learning to analyze clusters of symptoms […]
Jan 10, 2023
Data-driven identification of post-acute SARS-CoV-2 infection subphenotypes
(Nature) The post-acute sequelae of SARS-CoV-2 infection (PASC) refers to a broad spectrum of symptoms and signs that are persistent, exacerbated or newly incident in the period after acute SARS-CoV-2 infection. Most studies have examined these conditions individually without providing evidence on co-occurring conditions. In this study, we leveraged the electronic health record data of […]
Jan 10, 2023
Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate
(Nature)Vaccines against SARS-CoV-2 have been shown to be safe and effective but their protective efficacy against infection in the brain is yet unclear. Here, in the susceptible transgenic K18-hACE2 mouse model of severe coronavirus disease 2019 (COVID-19), we report a spatiotemporal description of SARS-CoV-2 infection and replication through the brain. SARS-CoV-2 brain replication occurs primarily […]
Jan 10, 2023
Most people who ended up with long COVID started with a mild case, new study shows
(CBS News) Even mild COVID-19 cases can have major and long-lasting effects on people’s health. That is one of the key findings from our recent multicountry study on long COVID-19 – or long COVID – recently published in the Journal of the American Medical Association. Long COVID is defined as the continuation or development of symptoms three months after the […]
Jan 10, 2023
Omicron COVID booster cuts hospitalization in over 65s, Israeli study finds
(Reuters) The Omicron-adapted COVID-19 vaccine booster developed by Pfizer Inc (PFE.N) and BioNTech SE (22UAy.DE) sharply reduced hospitalizations among older patients, Israeli researchers said on Monday, in some of the first evidence of the jab’s real-world effectiveness.
Jan 9, 2023
FDA releases important information about risk of COVID-19 due to certain variants not neutralized by Evusheld
(FDA) FDA is closely monitoring the emergence of the XBB.1.5 subvariant, a SARS-CoV-2 Omicron variant that is currently estimated to account for 28% of circulating variants in the U.S. Because of its similarity to variants that are not neutralized by Evusheld (e.g., XBB), FDA does not anticipate that Evusheld will neutralize XBB.1.5. This means that Evusheld may […]
Jan 9, 2023
People who haven’t had COVID will likely catch XBB.1.5 – and many will get reinfected, experts say
(USA Today) Variant XBB.1.5 is very contagious, meaning everyone is at risk even if you’ve already been infected. As the U.S. enters year 3 of the pandemic, here’s an update on the state of COVID. The newest COVID-19 variant is so contagious that even people who’ve avoided it so far are getting infected and the roughly 80% of […]
Jan 9, 2023
Pandemic response gets a permanent new home at the White House
(STAT News) The era of the rotating cast of public health czars at the White House may finally be over. Presidents for decades have brought fresh faces to the White House to coordinate federal responses to threats such as Covid-19, mpox, Ebola, AIDS, and the bird flu. Now, Congress aims to give pandemic response a permanent home […]
Jan 3, 2023
Comparative effectiveness of third doses of mRNA-based COVID-19 vaccines in US veterans
(Nature) Vaccination against SARS-CoV-2 has been effective in reducing the burden of severe disease and death from COVID-19. Third doses of mRNA-based vaccines have provided a way to address waning immunity and broaden protection against emerging SARS-CoV-2 variants. However, their comparative effectiveness for a range of COVID-19 outcomes across diverse populations is unknown. We emulated […]
Jan 3, 2023