University of Nebraska Medical Center
University of Nebraska Medical Center

Category: TB

Safety and immunogenicity of a thermostable ID93 + GLA-SE tuberculosis vaccine candidate in healthy adults

Nature Adjuvant-containing subunit vaccines represent a promising approach for protection against tuberculosis (TB), but current candidates require refrigerated storage. Here we present results from a randomized, double-blinded Phase 1 clinical trial (NCT03722472) evaluating the safety, tolerability, and immunogenicity of a thermostable lyophilized single-vial presentation of the ID93 + GLA-SE vaccine candidate compared to the non-thermostable two-vial vaccine […]

Mar 7, 2023

Temperature-Stable TB Vaccine Safe, Prompts Immune Response in NIH-Supported Study

NIH A clinical trial testing a freeze-dried, temperature-stable experimental tuberculosis (TB) vaccine in healthy adults found that it was safe and stimulated both antibodies and responses from the cellular arm of the immune system. The Phase 1 trial was supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes […]

Mar 7, 2023

Delaware County confirms tuberculosis case at William Penn School District

(NPR) The Delaware County Health Department is confirming a case of tuberculosis at Penn Wood Middle School in the William Penn School District. The district notified the county Health Department on Sunday. Health officials are working in concert with the district to locate people who may have been exposed to the individual. “The general public […]

Jan 24, 2023

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