Category: Published Research
(PLoS Pathogens) Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. Little is known about the role of mutations in the viral neuraminidase (NA) that accompanied bird-to-human transmission to support AIV infection of mammals. Here, after detailed analysis […]
Feb 8, 2023
First molecular detection of SARS-CoV-2 virus in cockroaches
Biologia Coronavirus is one of the main pathogens that primarily targets the human respiratory system. There are several ways to transmit this virus, such as direct contact or droplets spread by coughing or sneezing, and direct contact with fomites and surfaces is another way. This cross-sectional study was conducted in Shiraz, southern Iran, in 2021. […]
Feb 7, 2023
Highly pathogenic avian influenza A(H5N1) virus infection in farmed minks, Spain, October 2022
(Eurosurveillance) This report describes an outbreak of highly pathogenic avian influenza (HPAI) A(H5N1) detected in intensively farmed minks in Europe, which occurred in the Galicia region in northwest Spain in October 2022. We present an in-depth description of the epidemiological, clinical and genetic investigations of this outbreak affecting a single farm and discuss public health […]
Jan 31, 2023
Plasma from patients with pulmonary embolism show aggregates that reduce after anticoagulation
(Nature) Background Microclots, a term also used for amyloid fibrin(ogen) particles and henceforth named aggregates, have recently been reported in the plasma of patients with COVID-19 and long COVID. These aggregates have been implicated in the thrombotic complications of these diseases. Methods Plasma samples from 35 patients with acute pulmonary embolism were collected and analysed […]
Jan 31, 2023
Planning for Mpox on a College Campus: A Model-Based Decision-Support Tool
(Annals of Internal Medicine) In spring and summer 2022, an outbreak of mpox occurred worldwide, largely confined to men who have sex with men (MSM). There was concern that mpox could break swiftly into congregate settings and populations with high levels of regular frequent physical contact, like university campus communities. Objective: To estimate the likelihood […]
Jan 31, 2023
A systematic review and meta-analysis of the evidence on learning during the COVID-19 pandemic
(Nature) To what extent has the learning progress of school-aged children slowed down during the COVID-19 pandemic? A growing number of studies address this question, but findings vary depending on context. Here we conduct a pre-registered systematic review, quality appraisal and meta-analysis of 42 studies across 15 countries to assess the magnitude of learning deficits […]
Jan 31, 2023
(JAMA) Question Where does COVID-19 rank as an underlying cause of death for children and young people aged 0 to 19 years in the US? Findings Among children and young people aged 0 to 19 years in the US, COVID-19 ranked eighth among all causes of deaths, fifth in disease-related causes of deaths (excluding unintentional injuries, assault, […]
Jan 31, 2023
Assessment of Efficacy and Safety of mRNA COVID-19 Vaccines in Children Aged 5 to 11 Years
(JAMA Pediatrics) Are messenger RNA (mRNA) COVID-19 vaccines safe and effective in children aged 5 to 11 years? In this systematic review and meta-analysis including 17 studies with 10 935 541 vaccinated and 2 635 251 unvaccinated children aged 5 to 11 years, COVID-19 vaccination was associated with lower risks of SARS-CoV-2 infection, symptomatic COVID-19, hospitalization, and multisystem inflammatory […]
Jan 24, 2023
Antigenic mapping of emerging SARS-CoV-2 omicron variants BM.1.1.1, BQ.1.1, and XBB.1
(The Lancet) Novel SARS-CoV-2 omicron variants, including BM.1.1.1, BQ.1.1, and XBB.1, continue to emerge at an unprecedented rate, evading pre-existing immunity from vaccination and previous infection. Quantifying the antigenic diversity of variants might assist in selecting future vaccine strains. To determine the antigenic relationships between emerging SARS-CoV-2 omicron variants, we and others used antigenic cartography, […]
Jan 17, 2023
(BMJ) Despite a growing body of research on the risks of SARS-CoV-2 infection during pregnancy, there is continued controversy given heterogeneity in the quality and design of published studies. We screened ongoing studies in our sequential, prospective meta-analysis. We pooled individual participant data to estimate the absolute and relative risk (RR) of adverse outcomes among pregnant […]
Jan 17, 2023