Category: Published Research
Climate-driven changes in zoonotic risk of arenaviral hemorrhagic fevers in South America
Nature Climate change is expected to significantly alter the ecological dynamics of zoonotic diseases, yet its long-term impact on rodent-borne hemorrhagic fevers in South America remains poorly understood. Here, we developed a robust predictive modeling framework that integrates species distribution models with a mechanistic force-of-infection approach to evaluate the effects of climate change on zoonotic […]
Apr 15, 2026
Wildlife trade drives animal-to-human pathogen transmission over 40 years
Science The closer and longer the contact between species, the higher the chances of transmission of pathogens. This rule of thumb applies to human-to-human contacts as well as contacts with other species. Gippet et al. examined trade data for wildlife species from the past 40 years and showed that the longer a species had been legally […]
Apr 15, 2026
ChatGPT Health performance in a structured test of triage recommendations
Nature ChatGPT Health launched in January 2026 as OpenAI’s consumer health tool, reaching millions of users. Here, we conducted a structured stress test of triage recommendations using 60 clinician-authored vignettes across 21 clinical domains under 16 factorial conditions (960 total responses). Performance followed an inverted U-shaped pattern, with the most dangerous failures concentrated at clinical […]
Feb 25, 2026
The expanding H5N1 avian influenza panzootic causes high mortality of skuas in Antarctica
Nature High pathogenicity avian influenza virus H5N1 subtype (H5N1 HPAIV), clade 2.3.4.4b, is expanding its host and geographical range, and invaded Antarctica in 2023. Although mortality in Antarctic wildlife from H5N1 HPAIV has been suspected, mainly based on virological analysis of swabs collected from dead animals, it has not been unequivocally diagnosed. Here we show […]
Jan 14, 2026
Tiger deaths in Vietnam due to infection with H5N1 highly pathogenic avian influenza virus bearing mutations associated with mammalian host adaptation
NIH Abstract Recently, infections with the H5N1 subtype of highly pathogenic avian influenza virus (H5N1-HPAIV) in mammals have been reported worldwide, including in cows in the United States and successive human cases in Cambodia. In Vietnam, 47 tigers and three leopards died from H5N1-HPAIV infection between August and October 2024. This study aimed to determine […]
Oct 29, 2025
This ‘minor’ bird flu strain has potential to spark human pandemic
Nature Experiments suggests H9N2 has adapted to human cells but cases of person-to-person transmission haven’t been reported yet. A bird flu virus that has often been ignored because it mostly causes minor disease in birds has the potential to cause a human pandemic, says a team that has tracked how the H9N2 virus has become […]
Oct 29, 2025
Long COVID associated with SARS-CoV-2 reinfection among children and adolescents in the omicron era (RECOVER-EHR): a retrospective cohort study
The Lancet Background Post-acute sequelae of SARS-CoV-2 infection (PASC) remain a major public health challenge. Although previous studies have focused on characterising PASC in children and adolescents after an initial infection, the risks of PASC after reinfection with the omicron variant remain unclear. We aimed to assess the risk of PASC diagnosis (U09.9) and symptoms […]
Oct 29, 2025
Long-term cardiovascular complications in COVID-19 survivors according to disease severity
Nature Post-sepsis syndrome is a major concern affecting sepsis survivors. COVID-19 increases the risk of long-term complications, but existing data lack detail on patient-specific factors and long-term cardiovascular complications, namely major adverse cardiovascular events (MACE). Our objective was to analyze and compare the MACE occurrence, among COVID-19 survivors, according to the severity of infection. Adults […]
Oct 29, 2025
SARS-CoV-2 mRNA vaccines sensitize tumours to immune checkpoint blockade
Nature Immune checkpoint inhibitors (ICIs) extend survival in many patients with cancer but are ineffective in patients without pre-existing immunity1,2,3,4,5,6,7,8,9. Although personalized mRNA cancer vaccines sensitize tumours to ICIs by directing immune attacks against preselected antigens, personalized vaccines are limited by complex and time-intensive manufacturing processes10,11,12,13,14. Here we show that mRNA vaccines targeting SARS-CoV-2 also […]
Oct 22, 2025
Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans
NEJM We conducted an observational study that used the electronic health records of the Department of Veterans Affairs to evaluate the effectiveness of the 2024–2025 Covid-19 vaccine among veterans who received the Covid-19 and influenza vaccines on the same day (164,132 participants) and in an active-comparator group of veterans who received the influenza vaccine only […]
Oct 15, 2025