Microgravity pushed evolution into corners of the phage we still don’t fully understand” The International Space Station (ISS) is a closed ecosystem, and the biology inside it — including its microbial residents — don’t necessarily behave the same way on our home planet.
To better understand how microbes may act differently in space, researchers at the University of Wisconsin-Madison studied bacteriophages — viruses that infect bacteria, also called phages — in identical settings both on the ISS and on Earth. Their results, published recently in the journal PLOS Biology, suggest that microgravity can delay infections, reshape evolution of both phages and bacteria and even reveal genetic combinations that may help the performance against disease-linked bacteria on Earth.
“Studying phage–bacteria systems in space isn’t just a curiosity for astrobiology; it’s a practical way to understand and anticipate how microbial ecosystems behave in spacecraft and to mine new solutions for phage therapy and microbiome engineering back home.” Dr. Phil Huss, a professor at the University of Wisconsin-Madison and one of the study’s lead authors, told Space.com.