Category: COVID
Study aims to understand how SARS-CoV-2 affects the brain long-term
Medical News – In addition to the lungs, COVID-19 also affects the central nervous system (CNS) through anoxic, viral neurotoxicity, inflammation, and cerebrovascular mechanisms. As a result, about one-third of COVID-19 patients develop different neurologic problems, such as seizures, loss of sense of smell or taste, and stroke. Related study in Translational Research and Clinical Interventions
Sep 29, 2022
Effectiveness of primary series and booster vaccination against SARS-CoV-2 infection and hospitalisation among adolescents aged 12–17 years in Singapore: a national cohort study
The Lancet – Singapore offered the BNT162b2 vaccine (tozinameran; Pfizer-BioNTech) to adolescents aged 12–17 years in May 18, 2021, and extended booster vaccines to this group in Jan 21, 2022. Literature on the effectiveness of primary series and booster vaccination among adolescents is scarce outside of Europe and North America. We aimed to determine primary […]
Sep 29, 2022
What comes after Omicron? New variants are emerging.
National Geographic – Infections over the last three months have been dominated by new sublineages of Omicron: BA.2, BA.2.12.1, BA.4., and BA.5. In the U.K., symptomatic infections have steadily increased since August 27—the day they hit lowest level this year—according to the ZOE COVID-19 study, an App-based project in which patients enter their symptoms on their […]
Sep 29, 2022
Mental Health During the COVID-19 Pandemic
NIH – Both SARS-CoV-2 and the COVID-19 pandemic have significantly affected the mental health of adults and children. In a 2021 study, nearly half of Americans surveyed reported recent symptoms of an anxiety or depressive disorder, and 10% of respondents felt their mental health needs were not being met. Rates of anxiety, depression, and substance […]
Sep 29, 2022
Repurposing existing drugs to fight new COVID-19 variants
Michigan State University – MSU researchers are using big data and AI to identify current drugs that could be applied to treat new COVID-19 variants. Finding new ways to treat the novel coronavirus and its ever-changing variants has been a challenge for researchers, especially when the traditional drug development and discovery process can take years. […]
Sep 29, 2022
Association of SARS-CoV-2 Seropositivity With Myalgic Encephalomyelitis and/or Chronic Fatigue Syndrome Among Children and Adolescents in Germany
JAMA – Question Is SARS-CoV-2 seropositivity associated with symptoms of myalgic encephalomyelitis and/or chronic fatigue syndrome (ME/CFS) in children and adolescents? Findings This cross-sectional study of hospital-based SARS-CoV-2 seroprevalence surveys in Germany compared seropositive and seronegative children and adolescents and identified an excess of possible ME/CFS symptoms with serological evidence of preceding SARS-CoV-2 infection. This association almost […]
Sep 28, 2022
Remdesivir resistance in transplant recipients with persistent COVID-19
Clinical Infectious Diseases – New mutations conferring resistance to SARS-CoV-2 therapeutics have important clinical implications. We describe the first cases of an independently acquired V792I RNA-dependent RNA polymerase mutation developing in renal transplant recipients after remdesivir exposure. Our work underscores the need for augmented efforts to identify concerning mutations and address their clinical implications. Download […]
Sep 28, 2022
SARS-CoV-2 mutation leads to resistance to remdesivir in 2 patients
CIDRAP – A report published yesterday in Clinical Infectious Diseases describes a new SARS-CoV-2 mutation that confers resistance to the COVID-19 antiviral drug remdesivir in two persistently infected kidney transplant recipients treated with immunosuppressive drugs. NYU researchers identified the V792I RNA-dependent 25 RNA polymerase mutation in the transplant patients, who were hospitalized and experienced life-threatening COVID-19 complications […]
Sep 28, 2022
Japan’s COVID herd immunity near 90% after Omicron wave, study says
Reuters – Japan’s population level immunity to COVID-19 has reached about 90% in major population areas after a recent Omicron wave, though that level of protection is likely to diminish in a matter of months, according to a study published on Tuesday.
Sep 28, 2022