Category: Published Research
Optical pooled screens shed light on Ebola infection
Nature Filoviruses, a group of negative-sense single-stranded RNA viruses that encompasses Ebola, Marburg and Sudan viruses, among others, cause frequent deadly outbreaks. While some therapies and vaccines have been developed, treatment options are still limited, and the need to better understand the interplay between host factors and viral infection throughout the viral life cycle is […]
Sep 10, 2025
Pregnancy reduces COVID-19 vaccine immunity against novel variants
Nature Pregnant women are at heightened risk for severe outcomes from infectious diseases like COVID-19, yet were not included in initial vaccine trials, which may contribute to low booster uptake (15% or lower). We explored the serological and cellular responses to COVID-19 mRNA booster vaccines (i.e., ancestral and BA.5) in pregnant and age-matched, non-pregnant females […]
Aug 13, 2025
Accelerated brain ageing during the COVID-19 pandemic
Nature The impact of SARS-CoV-2 and the COVID-19 pandemic on brain health is recognised, yet specific effects remain understudied. We investigate the pandemic’s impact on brain ageing using longitudinal neuroimaging data from the UK Biobank. Brain age prediction models are trained from hundreds of multi-modal imaging features using a cohort of 15,334 healthy participants. These […]
Jul 30, 2025
Increasing Predominance of Norovirus GII.17 over GII.4, United States, 2022–2025
CDC Norovirus is the leading cause of acute gastroenteritis outbreaks in the United States (1). Genetically, noroviruses are classified into 10 genogroups (GI–GX) and further into 48 genotypes and 60 P-types (2). Most outbreaks are caused by genogroup GI and GII viruses. During 2011–2024, GII.4 viruses have caused >50% of US outbreaks each season (defined […]
Jun 3, 2025
Mpox poses an ever-increasing epidemic and pandemic risk
Nature The human interaction with mpox has changed across its entire endemic range, revealing the endemic and pandemic risk of monkeypox virus and the current knowledge gaps on its biology that hamper virus control. Humans are an ecological niche for orthopoxviruses (OPXV) such as mpox, a niche originally filled by smallpox (variola virus; VARV). Since […]
Apr 1, 2025
Transmission dynamics of the 2022 mpox epidemic in New York City
Nature The 2022 global mpox epidemic was caused by transmission of MPXV clade IIb, lineage B.1 through sexual contact networks, with New York City (NYC) experiencing the first and largest outbreak in the United States. By performing phylogeographic analysis of MPXV genomes sampled from 757 individuals in NYC between April 2022 and April 2023, and […]
Mar 26, 2025
Exposure and survival of wild raptors during the 2022–2023 highly pathogenic influenza a virus outbreak
Nature The global outbreak of clade 2.3.4.4b H5N1 highly pathogenic influenza A virus (HP H5N1) has had an unprecedented impact on wild birds including raptors, but long-term population impacts have not been addressed. To determine if raptors survive infections with HP H5N1, raptors from the upper Midwest United States were serologically tested for antibodies to […]
Feb 26, 2025
Incidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study
Journal of Internal Medicine Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) may occur after infection. How often people develop ME/CFS after SARS-CoV-2 infection is unknown. Objective To determine the incidence and prevalence of post-COVID-19 ME/CFS among adults enrolled in the Researching COVID to Enhance Recovery (RECOVER-Adult) study. Design, Setting, and Participants RECOVER-Adult is a longitudinal observational […]
Jan 14, 2025
Evidence of Influenza A(H5N1) Spillover Infections in Horses, Mongolia
CDC Recent outbreaks of influenza A(H5N1) have affected many mammal species. We report serologic evidence of H5N1 virus infection in horses in Mongolia. Because H3N8 equine influenza virus is endemic in many countries, horses should be monitored to prevent reassortment between equine and avian influenza viruses with unknown consequences. Avian influenza viruses (AIVs) of the […]
Jan 7, 2025
The Emerging Threat of H5N1 to Human Health
NEJM Highly pathogenic avian influenza (HPAI) A(H5N1) emerged in 1997.1 Since then, it has spread globally by migratory birds, resulting in infections in animals on every continent. HPAI A(H5N1) clade 2.3.4.4b emerged in 2021 and resulted in fatal infections in poultry as well as terrestrial and marine mammals.1 In early 2024, influenza A infection was first recognized […]
Jan 7, 2025