University of Nebraska Medical Center

Clinical Trials

Participants are able to take a more active role in their own health care, gain access to new drugs and treatments before they become widely available, and help other patients by contributing to medical research. Information on sponsored studies is available at ClinicalTrials.gov.

Current Transplant Clinical Studies

  1. Intestinal Transplant Registry. Comprehensive registry of all recipients of small intestine transplants throughout the world.
    PI: Alan Langnas

  2. Pediatric Liver Unresectable Tumor Observatory (PLUTO). A multicenter research registry to collect scientific data on pediatric liver tumors.
    PI: Alan Langnas

  3. A Phase II Randomized Multicenter Placebo-Controlled Blinded Study of Sorafenib Adjuvant Therapy in High Risk Orthotopic Liver Transplant (OLT) Recipients with Hepatocellular Carninoma (HCC).
    PI: Alan Langnas

  4. A Prospective, Multicenter Comparison of Multiphase Contrast-Enhanced CT and Multiphase Contrast-Enhanced MRI for Diagnosis of Hepatocellular Carcinoma and Liver Transplant Allocation.
    PI: Wendy Grant

  5. A Collaborative Islet Registry. Collection, analysis and communication of comprehensive and current data on all islet transplants.
    PI: Luciano Vargas

  6. A Multicenter, Randomized, Open-Label, Active-Controlled, Trial to Evaluate the Safety and Efficacy of Rifaximin 550mg With and Without Lactulose in Subjects With a History of Recurrent Overt Hepatic Encephalopathy.
    PI: Timothy McCashland

  7. Isolation, Storage and Transplantation of Human Hepatocytes for Development of Animal Models of Human Liver Disease.
    PI: David F. Mercer

  8. Studies of Inflammation, Immune Function and Infection in Intestinal Failure Patients.
    PI: David F. Mercer

  9. A 12-Pharmacokinetic, Safety, and Pharmacodynamic Study of Teduglutide in Pediatric Subjects Aged 1 through 17 Years, with Short Bowel Syndrome who are Dependent on Parenteral Support-TED-C13-003.
    PI: David F. Mercer

  10. Prospective Evaluation of a Parenteral Omega-3 Fatty Acid Preparation (Omegaven) In Therapy of Patients with TPN-Induced Cholestasis.
    PI: David F. Mercer