Give to GCHS

- Our Expertise Overview
- Why Nebraska?
  Nebraska’s difference is an all-star, all-volunteer team that dedicated itself to being ready for any biocontainment crisis at any time.
- Leadership
  The Global Center is led by experts in biopreparedness and high-consequence infections research, education and clinical care.
- Scholars
  Our scholars represent the pinnacle of health security expertise and are integral to advancing the mission of the GCHS in the domains of clinical care, operational response, research and development, and training in health security, and emergency response. GCHS scholars play a critical role by contributing to strategic priorities, shaping initiatives, and advancing the GCHS’s global leadership.
- Affiliates
  Our affiliates are innovative experts collaborating to advance global health security.
- C-STARS
  C-STARS, the Center for Sustainment of Trauma Readiness Skills- Omaha is a collaboration between UNMC, Nebraska Medicine, and the Air Force Research Laboratory’s School of Aerospace Medicine. C-STARS Omaha works closely with UNMC’s Global Center for Health Security, iEXCEL, and the Nebraska Biocontainment Unit to take advantage of the medical center’s capabilities and expertise in biopreparedness training and research.
- Our Team
  Our team consists of a variety of professionals providing support and project management to further the Global Center for Health Security’s mission.
- Domains Overview
- Clinical Operations
  The Global Center for Health Security is the premier U.S. institution for management of high-consequence infections. Further, our clinical capabilities include biological, chemical, burn, and radiation domains.
- Education & Training
  Our expertise is now sought worldwide and officially sanctioned by the U.S. government. The GCHS is the home base to the national Training, Simulation, and Quarantine Center and the Nebraska Biocontainment Unit.
- Research
  The GCHS has laser-focused existing work by our leading scientists in fields like chemical weapons, drug discovery and public health.
- International Partnerships & Innovation
  The GCHS tackles the most pressing problems in emerging infectious diseases through international partnerships and innovation.
- Programs Overview
- Core Capabilities
  Learn about the GCHS’ 4 core capabilities: Emerging Pathogens Lab , Nebraska Biocontainment Unit , the National Quarantine Unit, and deployable teams.
- Core Programs
  The GCHS works with multiple core programs to enhance our capabilities to respond effectively to public health challenges.
- Partnerships
  The GCHS partners with many outside organizations to strengthen our commitment to addressing global health challenges through research and innovation.
- Associated Groups & Programs
  Learn more about the impactful programs led by GCHS leadership, scholar, and affiliates.
- Academic Programs
  Explore GCHS academic programs which include the Health Security Fellowship and the Biological Defense and Health Security program.
- Health Emergencies Overview
- Outbreaks to Watch
  Find information about emerging pathogens, diseases and outbreaks from around the world. Stay updated on the most recent information on worldwide global health and emerging pathogens outbreaks.
- Measles
  The GCHS is currently monitoring measles cases. This page provides information, resources, and news.
- HPAI H5N1- Avian Influenza
  Learn more about the current worldwide outbreak of HPAI H5N1- Avian Influenza and explore resources, news, webinars, and our unofficial map.
- COVID-19
  Explore our COVID-19 page for recent news, resources, manuals, and playbooks. Biweekly overviews of new data and developments presented by James V. Lawler, MD, MPH, FIDSA can now be found on the Health Emergencies page.
- Mpox
  The Global Center for Health Security is currently monitoring the spread of mpox. Learn more by viewing our resources.
- Marburg Virus Disease
  Explore this page for comprehensive resources, information, news, and situational updates on the ongoing Marburg Virus Disease outbreak.
The Transmission
- News Overview
- Events
  Find scheduled and past events involving the Global Center for Health Security.
- Annual Reports
  Find annual reports for our center and several of our programs.
- Videos
  Watch our Year in Review videos, ISTARI videos, and more!

Author: Claudinne Miller

In vitro evolution of H5N1 avian influenza virus toward human-type receptor specificity

(Virology) Acquisition of α2-6 sialoside receptor specificity by α2-3 specific highly-pathogenic avian influenza viruses (H5N1) is thought to be a prerequisite for efficient transmission in humans. By in vitro selection for binding α2-6 sialosides, we identified four variant viruses with amino acid substitutions in the hemagglutinin (S227N, D187G, E190G, and Q196R) that revealed modestly increased α2-6 and […]

Jan 5, 2012