Category: Monkeypox
US government exercises $144m option for smallpox/mpox vaccine contract
Pharmaceutical Technology The options are for the freeze-dried version of Bavarian Nordic’s Jynneos, a formulation that allows easier stockpiling. Amid a US measles outbreak the US government has placed a $143.6m order for Bavarian Nordic’s smallpox/mpox jab Jynneos to bolster its infectious disease preparedness. The order is part of a ten-year contract awarded to vaccine-developer […]
May 7, 2025
Stockpiling for mpox emergencies
Gavi Recent outbreaks of mpox have highlighted the global threat posed by this virus. Historically an infection that circulated in animals and only occasionally affected humans, mpox is increasingly spreading from person to person through close contact, causing a painful rash, fever, headache, muscle ache, backache, swollen lymph nodes, chills and exhaustion. Depending on the strain, it […]
Apr 30, 2025
Mpox found in North Carolina wastewater testing samples: What that means
15 News North Carolina health officials are warning the public and medical practitioners to be on alert after a type of mpox never before found in the state was detected during routine wastewater testing. In an April 22 news release, the North Carolina Department of Health and Human Services (NCDHHS) said the virus—formerly known as monkeypox—was found during […]
Apr 23, 2025
Mpox testing gaps raise risk of cross-border spread
The Independent Foreign aid cuts could result in a major outbreak of mpox across the African continent and beyond, with virus control measures already disrupted, public health experts warn. Mpox testing and monitoring efforts in hotspot areas like the Democratic Republic of Congo (DRC) were heavily reliant on foreign assistance, which has been slashed under […]
Apr 16, 2025
New ‘surprising’ case of mpox variant clade lb detected in England
Retuers Britain’s health security agency said on Monday another case of the mpox variant clade lb had been detected in England in a person who had no reported travel history or link with previously confirmed cases in the country. The case was diagnosed in March and all contacts have been followed up and no further […]
Apr 9, 2025
An animal source of mpox emerges — and it’s a squirrel
Nature Researchers solve the mystery of a disease outbreak through long-term surveillance of wildlife in Africa. One of the great mysteries of the monkeypox virus has been pinpointing its ‘reservoir’ hosts — the animals that carry and spread the virus without becoming sick from it. Now, an international team of scientists suggests that it has an answer: […]
Apr 9, 2025
New ‘surprising’ case of mpox variant clade lb detected in England
Reuters Britain’s health security agency said on Monday another case of the mpox variant clade lb had been detected in England in a person who had no reported travel history or link with previously confirmed cases in the country. The case was diagnosed in March and all contacts have been followed up and no further […]
Apr 8, 2025
Research highlights rising risk of human-to-human mpox transmission
Medical News Mpox has the potential to become a significant global health threat if taken too lightly, according to scientists at the University of Surrey. In a letter published in Nature Medicine, researchers highlight how mpox – traditionally spread from animals to humans – is now showing clear signs of sustained human-to-human transmission. Mpox is a […]
Apr 2, 2025
FDA approves Bavarian Nordic’s freeze-dried mpox and smallpox vaccine
Pharmaceutical Technology The formulation allows for greater stockpiling, with Bavarian Nordic already working with the US Government to add to vaccine reserves. The US Food and Drug Administration (FDA) has approved the freeze-dried formulation of Bavarian Nordic’s smallpox and mpox vaccine in a move expected to provide flexibility in stockpiling the jab. Marketed as Jynneos […]
Apr 2, 2025
Mpox poses an ever-increasing epidemic and pandemic risk
Nature The human interaction with mpox has changed across its entire endemic range, revealing the endemic and pandemic risk of monkeypox virus and the current knowledge gaps on its biology that hamper virus control. Humans are an ecological niche for orthopoxviruses (OPXV) such as mpox, a niche originally filled by smallpox (variola virus; VARV). Since […]
Apr 1, 2025