Amanda J. Brinkworth, PhD

Department Affiliations
Assistant Professor

Survival of pathogenic bacteria during environmental stress through transcriptional and translational adaptation mechanisms.

Education and Training
PhD, Microbiology, University of Louisville School of Medicine, KY, 2011
MS, Microbiology, University of Louisville School of Medicine, KY, 2007
BS, Biology, Indiana University, Bloomington, IN, 2006

Notable Publications
Brinkworth AJ, Wildung MA, Carabeo, RA. Genomewide Transcriptional Responses of Iron-Starved Chlamydia trachomatis Reveal Prioritization of Metabolic Precursor Synthesis over Protein Translation. mSystems. 2018 Feb 13:3(1): e00184-17.

Kobayashi SD, Porter AR, Dorward DW, Brinkworth AJ, Chen L, Kreiswirth BN, DeLeo FR. Phagocytosis and killing of carbapenem-resistant ST258 Klebsiella pneumoniae by human neutrophils. Journal of Infectious Diseases. 2016 May 15; 213(10): 1615-22.

Brinkworth AJ, Hammer CH, Olano LR, Kobayashi SD, Chen L, Kreiswirth BN, DeLeo FR. (2015) Identification of outer membrane and exoproteins of the carbapenem-resistant strain K.pneumoniae ST258. PLoS One. 2015 Apr 20; 10(4): e0123219.

Brinkworth, AJ.; Malcom, DS.; Pedrosa, AT.; Roguska, K; Shahbazian, S.; Graham, JE; Hayward, RD; Carabeo, RA. (2011) Chlamydia trachomatis Slc1 is a type III secretion chaperone that enhances the translocation of its invasion effector substrate TARP. Mol Microbiol 82(1): 134-144.