Steven D. Carson, PhD

Department Affiliations
Professor, in transition to retirement and Professor Emeritus

Coxsackievirus, Adenovirus cell surface Receptor (CAR), Blood Coagulation (tissue factor), Cell Membranes, Protein Chemistry

Please see Dr. Carson's lab for details on his research, as well as his work with the Enterovirus Research Group.

Education and Training
BA, Rice University, 1973
PhD, University of Texas Graduate School of Biomedical Sciences, 1978
NSF, National Needs Postdoctoral Fellow, Yale University School of Medicine, 1978-1979
NIH Individual Research Service Award, Yale University School of Medicine, 1979-1981

Teaching History
Medical Students - Lectures on Blood Coagulation
Graduate students - Graduate student supervisor/mentor
PAMM 940 Molecular Basis of Human Disease (with Dr. Maurice Godfrey)

Notable Publications 

Carson, S.D., and W.H. Konigsberg. 1980. Cadmium increases tissue factor (coagulation factor III) activity by facilitating its reassociation with lipids.  Science 208:307-309.

Carson, S.D. 1981. Plasma high density lipoproteins inhibit the activation of factor X by factor VIIa and tissue factor (factor III). FEBS Letts. 132:37-40.

Carson, S.D., W.M. Henry, and T.B. Shows. 1985. Tissue factor gene localized to human chromosome 1 (1pter-1p21). Science 229:991-993.

Carson, S.D., S.E. Ross, R. Bach, and A. Guha. 1987. An inhibitory monoclonal antibody against human tissue factor.  Blood 70:490-493.

Carson, S.D. 1987. Continuous chromogenic tissue factor assay: Comparison to clot-based assays and sensitivity established using pure tissue factor.  Thrombos. Res. 47:379-387.

Faulk, W.P., C.A. Labarrere, and S.D. Carson. 1990. Tissue factor: Identification and characterization of cell types in human placentae. Blood 76:86-96.

Carson, S.D., N.M. Chapman, and S.M. Tracy. 1997. Purification of the putative coxsackievirus B receptor from HeLa cells. Biochem. Biophys. Res. Commun. 233:325-328.

McComb, R.D., K.A. Miller, and S.D. Carson. 1991. Tissue factor antigen in
senile plaques of Alzheimer's disease. Am. J. Path. 139:491-494.

Carson, S.D., N.M. Chapman, and S.M. Tracy. 1997. Purification of the putative coxsackievirus B receptor from HeLa cells. Biochem. Biophys. Res. Commun. 233:325-328.

Mody, R.S. and S.D. Carson. 1997. Tissue factor cytoplasmic domain peptide is multiply phosphorylated in vitro. Biochemistry 36:7869-7875.

Carson, S.D., J.T. Hobbs, S.M. Tracy, and N.M. Chapman. 1999. Expression of the coxsackievirus and adenovirus receptor in cultured human umbilical vein endothelial cells: regulation in response to cell density. J. Virol. 73:7077-7079.

Carson, S.D. 2004. Coxsackievirus and adenovirus receptor (CAR) is modified and shed in membrane vesicles. Biochemistry 43:8136-8142.

Carson, S.D., N.M. Chapman, S. Hafenstein, and S. Tracy. 2011. Variation of coxsackievirus B3 capsid primary structure, ligands, and stability are selected in a coxsackievirus and adenovirus receptor-limited environment. J. Virol. 85:3306-3314.

Organtini, L. J., A. M. Makhov, J. F. Conway, S. Hafenstein, and S. D. Carson. 2014. Kinetic and structural analysis of coxsackievirus B3 receptor interactions and formation of the A-particle. J. Virol. 88:5755-5765.

Carson, S. D. 2014. Kinetic models for receptor-catalyzed conversion of
coxsackievirus B3 to A-particles. J. Virol. 88:11568-11575.

Carson, S. D., and A. J. Cole. 2020. Albumin enhances the rate at which
coxsackievirus B3 strain 28 converts to A-particle. J. Virol. 94:1-17

Dr. Carson's personal website.

For a detailed list of publications, click here.