Current Graduate Students

Integrative Physiology & Molecular Medicine (IPMM) students


Weilun Ai
– 2nd year PhD IPMM student Weilun Ai
BS (Medicine), Jianghan University; MSc (Cell Biology), Capital Medical University
Supervisor:  Saraswathi Viswanathan
Research Interest: Non-alcoholic fatty liver disease and obesity-linked metabolic disease.

 

Upendra Chalise – 3rd year PhD IPMM student Upendra Chalise
B Pharmacy, Tribhuvan University
Supervisor:  Merry L. Lindsey
Research Interest: Studying potential resolution promoting factors which promotes wound healing after Myocardial infarction.

  • Tenkorang MAA, Chalise U, Daseke Ii MJ, Konfrst SR, Lindsey ML.  Understanding the mechanisms that determine extracellular matrix remodeling in the infarcted myocardium.  Biochem Soc Trans. 2019 Dec 20; 47(6):1679-1687.  Abstract
  • Daseke MJ 2nd, Tenkorang-Impraim MAA, Ma Y, Chalise U, Konfrst SR, Garrett MR, DeLeon-Pennell KY, Lindsey ML. Exogenous IL-4 shuts off pro-inflammation in neutrophils while stimulating anti-inflammation in macrophages to induce neutrophil phagocytosis following myocardial infarction. J Mol Cell Cardiol. 2020 Aug; 145:112-121. Abstract
  • Daseke MJ 2nd, Tenkorang MAA, Chalise U, Konfrst SR, Lindsey ML. Cardiac fibroblast activation during myocardial infarction wound healing: Fibroblast polarization after MI. Matrix Biol. 2020 Sep;91-92:109-116. Abstract

 

Safwan Elkhatib – 3rd year PhD IPMM student (M.D./Ph.D. Scholar)Safwan Elkhatib
BS (Kinesiology & Health), Iowa State University
Supervisors:  Adam J. Case and Kaushik P. Patel
Research Interest: How does extreme psychological stress (i.e., PTSD) modulate neuroimmune interactions to predispose patients to hypertension?

  • Elkhatib SK, Moshfegh CM, Watson GF, Case AJ. Peripheral inflammation is strongly linked to elevated zero maze behavior in repeated social defeat stress. Brain Behav Immun. 2020 Sep 2:S0889-1591(20)30827-8. Abstract
  • Elkhatib SK, Case AJ. Autonomic regulation of T-lymphocytes: Implications in cardiovascular disease. Pharmacol Res. 2019 Jun 6; 146:104293.  Abstract
  • Moshfegh CM, Elkhatib SK, Collins CW, Kohl AJ, Case AJ.  Autonomic and Redox Imbalance Correlates With T-Lymphocyte Inflammation in a Model of Chronic Social Defeat Stress.  Front Behav Neurosci. 2019 May 14; 13:103.  Abstract
  • Elkhatib SK, Neilsen BK, Sleightholm RL, Baine MJ, Zhen W.  A 47-year-old woman with nuclear protein in testis midline carcinoma masquerading as a sinus infection: a case report and review of the literature.  J Med Case Rep. 2019 Mar 11; 13(1):57.  Abstract

 

Adrian Flores - 2nd year PhD IPMM StudentAdrian Flores
BA (Biology), Roosevelt University
Supervisor: Gurudutt Pendyala
Research Interest: The vulnerability of pre and postnatal oxycodone exposed offspring to nicotine abuse.
  • Shahjin F, Guda RS, Schaal VL, Odegaard K, Clark A, Gowen A, Xiao P, Lisco SJ, Pendyala G, Yelamanchili SV. Brain-Derived Extracellular Vesicle microRNA Signatures Associated with In Utero and Postnatal Oxycodone Exposure.  Cells 2019 Dec 19; 9(1):21.  Abstract
  • Gowen A, Shahjin F, Chand S, Odegaard KE, Yelamanchili SV. Mesenchymal Stem Cell-Derived Extracellular Vesicles: Challenges in Clinical Applications.  Front Cell Dev Biol. 2020 Mar 12; 8:149.  Abstract
  • Azadmanesh J, Gowen AM, Creger PE, Schafer ND, Blankenship JR. Filamentation Involves Two Overlapping, but Distinct, Programs of Filamentation in the Pathogenic Fungus Candida albicans.  G3 (Bethesda). 2017 Nov 6; 7(11):3797-3808.  Abstract
 
Austin Gowen - 1st year PhD IPMM StudentAustin Gowen
BS (Biology), University of Nebraska - Omaha
Supervisor: Sowmya Yelamanchili
Research Interest: Pre-natal drug exposure and its impact on mild traumatic brain injury-related biological and behavioral sequelae
 
Taija Hahka - 2nd year PhD IPMM StudentTaija Hahka
BS (Biology), Doane College; M.S. (Physiology), UNMC
Supervisor: Hanjun Wang
Research Interest: Neural control & mechanisms that underlie cardiovascular and pulmonary responses; investigating diseases/disorders such as chronic heart failure, hypertension, COPD, & pain control.
 
Kajal Kamra - 2nd year PhD IPMM StudentKamra Kajal
BS (Zoology), University of Delhi; MS (Physiology), Wright State University
Supervisor: Harold D. Schultz
Research Interest: Physiology and molecular signaling pathways by which carotid body chemoreceptors regulate cardiovascular-respiratory function in health and disease.
 
Sumit KarSumit Kar - 3rd year PhD IPMM Student
BS (Biology), Creighton University
Supervisor: Paras Kumar Mishra
Research Interest: Hydrogen sulfide signaling and non-coding RNA in diabetic cardiomyopathy.
  • Mishra PK, Adameova A, Hill JA, Baines CP, Kang PM, Downey JM, Narula J, Takahashi M, Abbate A, Piristine HC, Kar S, Su S, Higa JK, Kawasaki NK, Matsui T.  Guidelines for evaluating myocardial cell death.  Am J Physiol Heart Circ Physiol. 2019 Nov 1; 317(5):H891-H922.   Abstract
  • Kar S, Shahshahan HR, Hackfort BT, Yadav SK, Yadav R, Kambis TN, Lefer DJ, Mishra PK.  Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy.  Antioxidants (Basel). 2019 Dec 11; 8(12). pii: E638.   Abstract
  • Kar S, Kambis TN, Mishra PK.  Hydrogen sulfide-mediated regulation of cell death signaling ameliorates adverse cardiac remodeling and diabetic cardiomyopathy.  Am J Physiol Heart Circ Physiol. 2019 Jun 1; 316(6):H1237-H1252.  Abstract
  • Kar S, Shahshahan HR, Kambis TN, Yadav SK, Li Z, Lefer DJ, Mishra PK.  Hydrogen Sulfide Ameliorates Homocysteine-Induced Cardiac Remodeling and Dysfunction.  Front Physiol. 2019 May 24; 10:598.  Abstract
  • Kambis TN, Shahshahan HR, Kar S, Yadav SK, Mishra PK.  Transgenic Expression of miR-133a in the Diabetic Akita Heart Prevents Cardiac Remodeling and Cardiomyopathy.  Front Cardiovasc Med. 2019 Apr 24; 6:45.  Abstract
 
Mane Polite Roneldine Mesidor - 1st year PhD IPMM StudentRoneldine Mesidor
BS (Biochemistry), Oklahoma Baptist University
Research Interest: Immunology and molecular biology
 
Corrine Monaco - 2nd year PhD IPMM StudentCorrine Monaco
BS (Zoology), State University of New York at Oswego
Supervisor: John S. Davis
Research Interest: Ovarian physiology
 
Cassandra Moshfegh - 4th year PhD IPMM StudentPicture of Cassandra Moshfegh
BS (Biology), George Washington University
Supervisor: Adam J. Case
Research Interest: Studying the regulation of immune cell functions in psychological stress models
  • Elkhatib SK, Moshfegh CM, Watson GF, Case AJ. Peripheral inflammation is strongly linked to elevated zero maze behavior in repeated social defeat stress. Brain Behav Immun. 2020 Sep 2:S0889-1591(20)30827-8. Abstract
  • Moshfegh CM, Case AJ. The Redox-Metabolic Couple of T Lymphocytes: Potential Consequences for Hypertension. Antioxid Redox Signal. 2020 Apr 30. Abstract
  • Yu Z, Swiercz AP, Moshfegh CM, Hopkins L, Wiaderkiewicz J, Speth RC, Park J, Marvar PJ.  Angiotensin II Type 2 Receptor-Expressing Neurons in the Central Amygdala Influence Fear-Related Behavior.  Biol Psychiatry. 2019 Dec 15;86(12):899-909.  Abstract
  • Moshfegh CM, Collins CW, Gunda V, Vasanthakumar A, Cao JZ, Singh PK, Godley LA, Case AJ.  Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes.  Redox Biol. 2019 Oct;27:101141. Abstract
  • Moshfegh CM, Elkhatib SK, Collins CW, Kohl AJ, Case AJ.  Autonomic and Redox Imbalance Correlates With T-Lymphocyte Inflammation in a Model of Chronic Social Defeat Stress.  Front Behav Neurosci. 2019 May 14; 13:103. Abstract
 
Sarah Schlichte - 4th year PhD IPMM StudentPicture of Sarah Schlichte
BS (Biology), Buena Vista University
Supervisor: Matthew C. Zimmerman
Research Interest: Mechanisms of SOD Mimics in Hypertension
  • Schlichte SL, Romanova S, Katsurada K, Kosmacek EA, Bronich TK, Patel KP, Oberley-Deegan RE, Zimmerman MC. Nanoformulation of the superoxide dismutase mimic, MnTnBuOE-2-PyP5+, prevents its acute hypotensive response. Redox Biol. 2020 Jun 20;36:101610. Abstract
  • Price ME, Gerald CL, Pavlik JA, Schlichte SL, Zimmerman MC, Devasure JM, Wyatt TA, Sisson JH.  Loss of cAMP-dependent stimulation of isolated cilia motility by alcohol exposure is oxidant dependent.  Alcohol. 2018 Oct 3. pii: S0741-8329(18)30170-8.  Abstract
  • Clemens DL, Duryee MJ, Sarmiento C, Chiou A, McGowan JD, Hunter CD, Schlichte SL, Tian J, Klassen LW, O'Dell JR, Thiele GM, Mikuls TR, Zimmerman MC, Anderson DR.  Novel Antioxidant Properties of Doxyclycline.  Int J Mol Sci. 2018 Dec 17;19(12).  Abstract
 
Zhiqiu (Claire) Xia - 5th year PhD IPMM Student Picture of Claire Xia
MD (Clinical Medicine) Sun Yat-Sen University
Supervisor: Hanjun Wang
Research Interest: Role of cardiac afferents in the cardiorenal axis in heart failure
  • Adam RJ, Xia Z, Pravoverov K, Hong J, Case AJ, Schultz HD, Lisco SJ, Zucker IH, Wang HJ.  Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure.  Am J Physiol Heart Circ Physiol. 2019 Apr 1; 316(4):H862-H872.  Abstract
  • Schiller AM, Hong J, Xia Z, Wang HJ.  Increased Brain-Derived Neurotrophic Factor in Lumbar Dorsal Root Ganglia Contributes to the Enhanced Exercise Pressor Reflex in Heart Failure.  Int J Mol Sci. 2019 Mar 24; 20(6). pii: E1480.  Abstract
  • Shanks J, Xia Z, Lisco SJ, Rozanski GJ, Schultz HD, Zucker IH, Wang HJ.  Sympatho-excitatory response to pulmonary chemosensitive spinal afferent activation in anesthetized, vagotomized rats.  Physiol Rep. 2018 Jun; 6 (12):e13742. Abstract
 

Other StudentsTyler Kambis

Tyler Kambis - 4th year PhD MGCB student
BS (Biology), Sheperd University
Supervisor: Paras Kumar Mishra
Research Interest: Diabetic cardiomyopathy
  • Kambis TN, Shahshahan HR, Kar S, Yadav SK, Mishra PK. Transgenic Expression of miR-133a in the Diabetic Akita Heart Prevents Cardiac Remodeling and Cardiomyopathy.Front Cardiovasc Med. 2019 Apr 24; 6:45. Abstract
  • Kar S, Shahshahan HR, Kambis TN, Yadav SK, Li Z, Lefer DJ, Mishra PK. Hydrogen Sulfide Ameliorates Homocysteine-Induced Cardiac Remodeling and Dysfunction. Front Physiol. 2019 May 24; 10:598. Abstract
  • Kar S, Kambis TN, Mishra PK. Hydrogen sulfide-mediated regulation of cell death signaling ameliorates adverse cardiac remodeling and diabetic cardiomyopathy. Am J Physiol Heart Circ Physiol. 2019 Jun 1; 316(6):H1237-H1252.  Abstract
  • Yadav SK, Kambis TN, Kar S, Park SY, Mishra PK. MMP9 mediates acute hyperglycemia-induced human cardiac stem cell death by upregulating apoptosis and pyroptosis in vitro. Cell Death Dis. 2020 Mar 13; 11(3):186.  Abstract
  • Kar S, Shahshahan HR, Hackfort BT, Yadav SK, Yadav R, Kambis TN, Lefer DJ, Mishra PK. Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy. Antioxidants (Basel). 2019 Dec 11; 8(12):638. Abstract
 
Michael John Daseke - PhD student, University of Mississippi Medical CenterJohn Daseke
BA (Biology), DePauw University
Supervisor: Merry L. Lindsey
  • Daseke MJ 2nd, Valerio FM, Kalusche WJ, Ma Y, DeLeon-Pennell KY, Lindsey ML. Neutrophil proteome shifts over the myocardial infarction time continuum. Basic Res Cardiol. 2019 Aug 15; 114(5):37. Abstract
  • Mouton AJ, Ma Y, Rivera Gonzalez OJ, Daseke MJ 2nd, Flynn ER, Freeman TC, Garrett MR, DeLeon-Pennell KY, Lindsey ML. Fibroblast polarization over the myocardial infarction time continuum shifts roles from inflammation to angiogenesis. Basic Res Cardiol. 2019 Jan 11; 114(2):6. Abstract
  • Kaminski AR, Moore ET, Daseke MJ 2nd, Valerio FM, Flynn ER, Lindsey ML. The compendium of matrix metalloproteinase expression in the left ventricle of mice following myocardial infarction. Am J Physiol Heart Circ Physiol. 2020 Mar 1; 318(3):H706-H714. Abstract
  • Daseke MJ 2nd, Tenkorang-Impraim MAA, Ma Y, Chalise U, Konfrst SR, Garrett MR, DeLeon-Pennell KY, Lindsey ML. Exogenous IL-4 shuts off pro-inflammation in neutrophils while stimulating anti-inflammation in macrophages to induce neutrophil phagocytosis following myocardial infarction. J Mol Cell Cardiol. 2020 Aug; 145:112-121. Abstract
  • Daseke MJ 2nd, Tenkorang MAA, Chalise U, Konfrst SR, Lindsey ML. Cardiac fibroblast activation during myocardial infarction wound healing: Fibroblast polarization after MI. Matrix Biol. 2020 Sep; 91-92:109-116. Abstract
 
Linda Berg Luecke - PhD student, Medical College of WisconsinLinda Berg Luecke
Supervisor: Rebekah L. Gundry
  • Berg Luecke L, Waas M, Gundry RL. Reliable Protocols for Flow Cytometry Analysis of Intracellular Proteins in Pluripotent Stem Cell Derivatives: A Fit-For-Purpose Approach.  Curr Protoc Stem Cell Biol. 2019 Sep;50(1):e94.  Abstract