Current Graduate Students

Weilun Ai – 1st year Ph.D. IPMM student Weilun Ai
B.S. (Medicine), Jianghan University; MSc (Cell Biology), Capital Medical University
Supervisor:  Saraswathi Viswanathan
Research Interest: Non-alcoholic fatty liver disease and obesity-linked metabolic disease.

Upendra Chalise – 2nd year Ph.D. IPMM student Upendra Chalise
B. Pharmacy, Tribhuvan University
Supervisor:  Merry L. Lindsey
Research Interest: Studying potential resolution promoting factors which promotes wound healing after Myocardial infarction.

  • Tenkorang MAA, Chalise U, Daseke Ii MJ, Konfrst SR, Lindsey ML.  Understanding the mechanisms that determine extracellular matrix remodeling in the infarcted myocardium.  Biochem Soc Trans. 2019 Dec 20; 47(6):1679-1687.  Abstract

Safwan Elkhatib – 2nd year Ph.D. IPMM student (M.D./Ph.D. Scholar)Safwan Elkhatib
B.S (Kinesiology & Health), Iowa State University
Supervisors:  Adam J. Case and Kaushik P. Patel
Research Interest: How does extreme psychological stress (i.e., PTSD) modulate neuroimmune interactions to predispose patients to hypertension?

  • Elkhatib SK, Case AJ. Autonomic regulation of T-lymphocytes: Implications in cardiovascular disease. Pharmacol Res. 2019 Jun 6; 146:104293.  Abstract
  • Moshfegh CM, Elkhatib SK, Collins CW, Kohl AJ, Case AJ.  Autonomic and Redox Imbalance Correlates With T-Lymphocyte Inflammation in a Model of Chronic Social Defeat Stress.  Front Behav Neurosci. 2019 May 14; 13:103.  Abstract
  • Elkhatib SK, Neilsen BK, Sleightholm RL, Baine MJ, Zhen W.  A 47-year-old woman with nuclear protein in testis midline carcinoma masquerading as a sinus infection: a case report and review of the literature.  J Med Case Rep. 2019 Mar 11; 13(1):57.  Abstract

Taija Hahka - 1st year Ph.D. IPMM StudentTaija Hahka
B.S. (Biology), Doane College; M.S. (Physiology), UNMC
Supervisor: Hanjun Wang
Research Interest: Neural control & mechanisms that underlie cardiovascular and pulmonary responses; investigating diseases/disorders such as chronic heart failure, hypertension, COPD, & pain control.

Cassie Hays - 3rd year Ph.D. IPMM StudentPicture of Cassie Hays
B.S. (Biology), Doane College; M.S. (Physiology), UNMC
Supervisor: Wallace B. Thoreson
Research Interest: Retinal physiology

  • Hays CL, Grassmeyer JJ, Wen X, Janz R, Heidelberger R, Thoreson WB.  Simultaneous Release of Multiple Vesicles from Rods Involves Synaptic Ribbons and Syntaxin 3B.  Biophys J. 2019 Oct 10. pii: S0006-3495(19)30853-7.  Abstract
  • Grassmeyer JJ, Cahill AL, Hays CL, Barta C, Quadros RM, Gurumurthy CB, Thoreson WB.  Ca2+ sensor synaptotagmin-1 mediates exocytosis in mammalian photoreceptors.  Elife. 2019 Jun 7;8. pii: e45946.  Abstract
  • Hays CL, Okafor KC, Fan S, High R, Singh DP, Toris CB.  Consequences of Puberty on Efficacy of Intraocular Pressure-Lowering Drugs in Male Dutch-Belted Rabbits. J Ocul Pharmacol Ther. 2018 Jan/Feb; 34(1-2):76-84. Abstract
  • Toris CB, Fan S, Johnson TV, Camras LJ, Hays CL, Liu H, Ishimoto BM.  Aqueous Flow Measured by Fluorophotometry in the Mouse. Invest Ophthalmol Vis Sci. 2016 Jul 1; 57(8):3844-52.  Abstract
Kajal Kamra - 1st year Ph.D. IPMM StudentKamra Kajal
B.S. (Zoology), University of Delhi; M.S. (Physiology), Wright State University
Supervisor: Harold D. Schultz
Research Interest: Physiology and molecular signaling pathways by which carotid body chemoreceptors regulate cardiovascular-respiratory function in health and disease.
Sumit KarSumit Kar - 2nd year Ph.D. IPMM Student
B.S. (Biology), Creighton University
Supervisor: Paras Kumar Mishra
Research Interest: Hydrogen sulfide signaling and non-coding RNA in diabetic cardiomyopathy.
  • Mishra PK, Adameova A, Hill JA, Baines CP, Kang PM, Downey JM, Narula J, Takahashi M, Abbate A, Piristine HC, Kar S, Su S, Higa JK, Kawasaki NK, Matsui T.  Guidelines for evaluating myocardial cell death.  Am J Physiol Heart Circ Physiol. 2019 Nov 1; 317(5):H891-H922.   Abstract
  • Kar S, Shahshahan HR, Hackfort BT, Yadav SK, Yadav R, Kambis TN, Lefer DJ, Mishra PK.  Exercise Training Promotes Cardiac Hydrogen Sulfide Biosynthesis and Mitigates Pyroptosis to Prevent High-Fat Diet-Induced Diabetic Cardiomyopathy.  Antioxidants (Basel). 2019 Dec 11; 8(12). pii: E638.   Abstract
  • Kar S, Kambis TN, Mishra PK.  Hydrogen sulfide-mediated regulation of cell death signaling ameliorates adverse cardiac remodeling and diabetic cardiomyopathy.  Am J Physiol Heart Circ Physiol. 2019 Jun 1; 316(6):H1237-H1252.  Abstract
  • Kar S, Shahshahan HR, Kambis TN, Yadav SK, Li Z, Lefer DJ, Mishra PK.  Hydrogen Sulfide Ameliorates Homocysteine-Induced Cardiac Remodeling and Dysfunction.  Front Physiol. 2019 May 24; 10:598.  Abstract
  • Kambis TN, Shahshahan HR, Kar S, Yadav SK, Mishra PK.  Transgenic Expression of miR-133a in the Diabetic Akita Heart Prevents Cardiac Remodeling and Cardiomyopathy.  Front Cardiovasc Med. 2019 Apr 24; 6:45.  Abstract
May MaAnyun (May) Ma - 5th year Ph.D. CIP Student
B.Med. Tongji University
Supervisor: Irving H. Zucker
Research Interest: The Interaction between Nrf2 and ACE2 in Angiotensin II-Induced Hypertension
  • Ma A, Hong J, Shanks J, Rudebush T, Yu L, Hackfort BT, Wang H, Zucker IH, Gao L.  Upregulating Nrf2 in the RVLM ameliorates sympatho-excitation in mice with chronic heart failure.  Free Radic Biol Med. 2019 Jun 7; 141:84-92.  Abstract
Corrine Monaco - 1st year Ph.D. IPMM StudentCorrine Monaco
B.S. (Zoology), State University of New York at Oswego
Supervisor: John S. Davis
Research Interest: Ovarian physiology
Cassandra Moshfegh - 3rd year Ph.D. IPMM StudentPicture of Cassandra Moshfegh
B.S. (Biology), George Washington University
Supervisor: Adam J. Case
Research Interest: Studying the regulation of immune cell functions in psychological stress models
  • Yu Z, Swiercz AP, Moshfegh CM, Hopkins L, Wiaderkiewicz J, Speth RC, Park J, Marvar PJ.  Angiotensin II Type 2 Receptor-Expressing Neurons in the Central Amygdala Influence Fear-Related Behavior.  Biol Psychiatry. 2019 Dec 15;86(12):899-909.  Abstract
  • Moshfegh CM, Collins CW, Gunda V, Vasanthakumar A, Cao JZ, Singh PK, Godley LA, Case AJ.  Mitochondrial superoxide disrupts the metabolic and epigenetic landscape of CD4+ and CD8+ T-lymphocytes.  Redox Biol. 2019 Oct;27:101141. Abstract
  • Moshfegh CM, Elkhatib SK, Collins CW, Kohl AJ, Case AJ.  Autonomic and Redox Imbalance Correlates With T-Lymphocyte Inflammation in a Model of Chronic Social Defeat Stress.  Front Behav Neurosci. 2019 May 14; 13:103. Abstract
Sarah Schlichte - 3rd year Ph.D. IPMM StudentPicture of Sarah Schlichte
B.S. (Biology), Buena Vista University
Supervisor: Matthew C. Zimmerman
Research Interest: Mechanisms of SOD Mimics in Hypertension
  • Price ME, Gerald CL, Pavlik JA, Schlichte SL, Zimmerman MC, Devasure JM, Wyatt TA, Sisson JH.  Loss of cAMP-dependent stimulation of isolated cilia motility by alcohol exposure is oxidant dependent.  Alcohol. 2018 Oct 3. pii: S0741-8329(18)30170-8.  Abstract
  • Clemens DL, Duryee MJ, Sarmiento C, Chiou A, McGowan JD, Hunter CD, Schlichte SL, Tian J, Klassen LW, O'Dell JR, Thiele GM, Mikuls TR, Zimmerman MC, Anderson DR.  Novel Antioxidant Properties of Doxyclycline.  Int J Mol Sci. 2018 Dec 17;19(12).  Abstract
Ahmed WafiAhmed Wafi - 5th year Ph.D. Student
B.Med. (Medicine & Surgery), Jazan University; M.S. (Exercise Physiology), University of Louisville
Supervisor: Irving H. Zucker
Research Interest: Effect of exercise training on Nrf2 protein expression in the central nervous system during chronic heart failure
  • Wafi AM, Yu L, Gao L, Zucker IH.  Exercise training upregulates Nrf2 protein in the rostral ventrolateral medulla of mice with heart failure.  J Appl Physiol (1985). 2019 Nov 1; 127(5):1349-1359.   Abstract
  • Wafi AM, Hong J, Rudebush TL, Yu L, Hackfort BT, Wang HJ, Schultz HD, Zucker IH, Gao L.  Curcumin Improves Exercise Performance of Mice with Coronary Artery Ligation Induced HFrEF: Nrf2 and Antioxidant Mechanisms in Skeletal Muscle.  J Appl Physiol (1985). 2018 Nov 21.  Abstract
Zhiqiu (Claire) Xia - 4th year Ph.D. IPMM Student Picture of Claire Xia
M.D. (Clinical Medicine) Sun Yat-Sen University
Supervisor: Hanjun Wang
Research Interest: Role of cardiac afferents in the cardiorenal axis in heart failure
  • Adam RJ, Xia Z, Pravoverov K, Hong J, Case AJ, Schultz HD, Lisco SJ, Zucker IH, Wang HJ.  Sympathoexcitation in response to cardiac and pulmonary afferent stimulation of TRPA1 channels is attenuated in rats with chronic heart failure.  Am J Physiol Heart Circ Physiol. 2019 Apr 1; 316(4):H862-H872.  Abstract
  • Schiller AM, Hong J, Xia Z, Wang HJ.  Increased Brain-Derived Neurotrophic Factor in Lumbar Dorsal Root Ganglia Contributes to the Enhanced Exercise Pressor Reflex in Heart Failure.  Int J Mol Sci. 2019 Mar 24; 20(6). pii: E1480.  Abstract
  • Shanks J, Xia Z, Lisco SJ, Rozanski GJ, Schultz HD, Zucker IH, Wang HJ.  Sympatho-excitatory response to pulmonary chemosensitive spinal afferent activation in anesthetized, vagotomized rats.  Physiol Rep. 2018 Jun; 6 (12):e13742. Abstract