Clinical Research
Dermatology Clinical Trials and Studies
Our department conducts clinical trials and participates in registries in these areas:
Skin Cancer & Prevention
- Incidence and Mortality of Melanoma and access to care in Nebraska.
- The efficiency of a multi-modal approach to sun-safety in skin cancer patients.
- Integration of patient, satisfaction, functional status and quality of life in determining appropriateness of skin cancer treatment in advanced age and high-risk patients.
- The Reveal Imager as an Intervention to Improve Sun-safety Behaviors
- Virtual Reality in Dermatologic Surgery
- Satisfaction of closing defects after facial skin cancer resection (SCAR) study
- The efficacy of an education e-module on patient understanding of melanoma prevention and early detection
- Postoperative complications, nasal function, and quality of life following interpolated flap repair for post-Mohs surgical defects of the nose: a multi-center prospective observational cohort study
Translational Squamous Cell Carcinoma & Personalized High-Risk Skin Cancer Care
- Cancer-associated genetic mutations and patterns of the tumor microenvironment in skin cancer
- Development and validation of a gene expression assay to predict the risk of recurrent disease in cutaneous squamous cell carcinoma
- IHC and high-risk squamous cell carcinoma
- Role of immunosupression in staging and gene expression of high-risk SCC
- UV dosimetry and reducation of sun exposure in transplant and other high-risk patients
- HIV and skin cancer
- Clinical Characterization Protocol for Severe Emerging Infections (COVID-19)
- The role of COVID-19 in cardiovascular disease & skin
- Autoimmune Skin Diseases
- Teledermatology and increasing access to care in agricultural populations
Other
- Quality of Life and Venolymphatic Disease: A prospective study
- Analysis of the impact of dermatology on patient care at an academic hospital
- A survey to assess the gender gap in academic medicine
Registries
The Integrated Cancer Respository for Cancer Research is a multi-institutional resource created and maintained by the Fred & Pamela Buffett Cancer Center to collect and manage standardized, multidimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. UNMC Dermatology is involved in iCaRe2 for melanoma, squamous cell carcinoma, basal cell carcinoma, merkel cell carcinoma and other rare cutaneous tumors.
For information about studies, email the Research Office or call 402-559-3825.
Studies Currently Enrolling
The efficacy of a multi-modal approach to sun-safety in skin cancer patients
To study how an interactive educational module and UV light tracker will influence sun safety knowledge and behavior. This knowledge will allow us to educate high-risk populations on how to minimize skin cancer risk.
To be eligible for this study, individuals must:
- Be 19 years or older and willing to participate.
- Have access to iPhone 7 or newer and the internet .
Teledermatology and increasing access to care in agricultural populations.
To study skin disease in agricultural populations. Currently enrolling patients in the Nebraska communities of Blue Hill, and Beatrice, and starting soon in Norfolk.
To be eligible for this study, individuals must:
- Work in agriculture or participate in agriculturally-related activities
- Have a dermatologic condition
- Be 19 years or older
Quality of Life and Venolymphatic Disease: A prospective study
To assess physical implications of chronic vascular disease on quality of life with the goal of validating the experiences of the patient and the efficacy of endovenous laser ablation and endovenous chemical ablation for this highly morbid disease.
To be eligible for this study, individuals must:
- Have chronic vascular disease
- Be 19 years or older
- Be able to provide informed consent
Dermatology Tissue Bank
The bank collects tissue and/or blood from patients with dermatologic conditions for the purpose of future genetic, cellular, molecular and clinical database studies
To be eligible for this study, individuals must:
- Have a dermatologic condition and be having a biopsy and/or blood drawn
- Be 19 years or older
- Be able to provide informed consent
Dermatology Patient Data Registry
This registry extracts and organizes information relevant to the presentation, course, management, and outcomes of patients with skin cancer, infectious, inflammatory, autoimmune, and rheumatologic conditions in addition to those patients seen on the inpatient and teledermatology consult service
To be eligible for this study, individuals must:
- Be seen at a clinic or outreach site associated with the UNMC Department of Dermatology.
- Be 19 years or older and willing to participate