10/2022-Present “NECTAR Trial: Novel Experimental COVID Therapies Affecting Host Response”. NHLBI funded. Site PI- Aaron Barksdale
03/2021-Present “ICECAP: Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients”. NHLBI/NINDS funded (SIREN Network). Site PI- Aaron Barksdale
09/2020-Present “Evaluation of Stressors related to COVID-19 in Emergency Medicine Physicians”. Emergency Medicine Foundation Grant. Site PI- Jordan Warchol
June 2020-Present “PsySTART Rapid Triage and Linkage for Emergency Department Providers During COVID-19”. CDC funded. Site PI- Aaron Barksdale. Total Funding- $150,001
June 2020-Present Healthcare Worker Exposure Response and Outcomes of Hydroxychloroquine Trial (HERO-HCQ Trial). PCORI funded. Site PI- Jim McClay. Total Funding-$533,678
09-2019-Present “Hyperbaric Oxygen Brain Injury Treatment (HOBIT) Trial”. SIREN/NIH funded. Site PI- Jeff Cooper
04-2019-Present Use of Methylene Blue in Acquired Methemoglobinemia: Prospective Observational Registry (metHb). Hospital Quality Foundation. Site PI Aaron Barksdale
2015-01/2020 ED-SAFE-2: Translating Safety Planning into Practice. Site PI- Wes Zeger Total Funding- $180,470
11/2018-01/2020 “VICTAS Trial”, A multi-center, randomized, placebo-controlled, ouble-blind, adaptive clinical trial of vitamin C, thiamine and steroids, as combination therapy in patients with sepsis. Marcus Foundation. Total funding- $86,185.84. Site PI- Aaron Barksdale
2/2015 – 1/2017 “AQT90 FLEX TnI and TnT – Clinical Sensitivity and Specificity Trial”, multi-center trial. Radiometer. Site PI- Aaron Barksdale. Total funding- $215,479.11
7/2015 – 1/2017 “Reverse AD Trial, evaluating the effectiveness of a reversal agent for dabigatran”, multi-center, opened ended phase III trial. Boehringer-Ingelheim. Site PI- Aaron Barksdale. Total funding- $33,999.09
12/2016 – 8/2017 “Sepsis-ACT”, multi-center trial, Selepression Evaluation Programme for Sepsis-Induced Shock-Adaptive Clinical Trail. Ferring. Site Co-I- Aaron Barksdale
5/2014 – 3/2016 “RELAX-AHF-2” Trial, A multicenter, randomized, double-blind, placebo-controlled phase IIIb study to evaluate the efficacy, safety, and tolerability of Serelaxin when added to standard therapy in acute heart failure patients. Novartis. Site Co-I- Aaron Barksdale
7/2014 – 9/2015 “SOCRATES” Trial (Acute Stroke Or Transient Ischemic Attack Treated with Aspirin or Ticagrelor and Patient Outcomes), A Randomized, Double-Blind, Multinational Study to Prevent Major Vascular Events with Ticagrelor Compared to Aspirin (ASA) in Patients with Acute Ischaemic Stroke or TIA. AstraZeneca. Site Co-I- Aaron Barksdale
June 2020-Current “PsySTART Rapid Triage and Linkage for Emergency Department Providers During COVID-19”. CDC funded. Site PI- Aaron Barksdale. Total Funding- $150,001
May 2020-Current Novel Self-collection respiratory pathogen specimen collection device. UNMC COVID-19 Rapids Response Grant. Site PI- Thang Nguyen, CoI-Wes Zeger, Make Wadman. Total Funding- $14,000
08/2017-04/2022 Novel target mechanism (renal denervation) to reduce sodium retention in chronic heart failure. NIH/NIDDK, 1R01DK114663-01 (Co-Investigator: Yu-Long Li). Total Funding- $2,072,021.
08/201/-07/2022 Potential therapies to improve ventricular vagal function in type 2 diabetes. NIH/NHLBI, 1R01HL144146-01 (Principal Investigator: Yu-Long Li). Total funding- $1,525,000
07/2017-06/2021 Mechanisms of cardiac sympathetic hyperactivity in chronic heart failure. NIH/NHLBI, 1R01HL137832-01 (Principal Investigator: Yu-Long Li). Total Funding $1,505,000.
06/2019-12/2020 Development of a Culturally Sensitive Domestic Violence, Child Abuse, and Sexual Assacult Infomred Care lectureship in Japan. United States-Japan Foundation. Site PI- Wes Zeger, CI- Thang Nguyen, Aaron Barksdale, Mike Wadman
01/2020-09/2020 Advancement of PCORnet Infrastructure: Clinical Research Network. Site PI- Jim McClay. Total Funding- $187,512
07/2016-08/2020 Aspirain Dosing: A Patient –Centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE). Site PI- Jim McClay, Total Funding-$85,800
07/2019-06-2020 Multi-layered vascularized cardiac patch for the treatment of chronic heart failure. University of Nebraska Collaboration Initiative Seed Grant (Co-Principal Investigator: Yu-Long Li). Total Funding- $150,000.
11/2018-02/2020 PCRF- PCORnet 2.0/PCRnet Clinical Research Network Infrastructure. Site PI- Jim McClay. Total Funding- $250,898
03/2017-08/2019 Optimized liposomal dexamethasone therapy improves functional outcome of post-traumatic skeletal muscle and neuromuscular junction. USAMRAA grant from Department of Defense, W81XWH-17-1-0037 (Principal Investigator: Yu-Long Li). Total Funding- $360,645.
08/2013-06/2019 Molecular and cellular determinants of the exercise pressor reflex in CHF. NIH/NHLBI, R01HL116608-01A1 (Co-Investigator: Yu-Long Li). Total Funding- $1,849,140
09/2015-03/2019 Greater Plains Collaborative Clinical Data Research Network. Site PI-Jim McClay. Total Funding-$399,000
09/2016-09/2018 Greate Plains Collaborative Clinic Data Research Network. Site PI- Jim McClay. Total Funding- $108,526
04/2017-09/2018 Dodecafluoropentane prevents ischemia reperfusion injury in contemporary acute myocardial infarction management. NIH/NHLBI, 1R43HL137545-01 (Co-Investigator: Yu-Long Li). Total Funding $317,743.
09/2017-05/2018 Greate Plains Collaborative Clinical Data Research Network. Site PI- Jim McClay. Total Funding- $77,003
02/2016-01/2018 PCORNet Bariatric Study. Site PI- Jim McClay. Total Funding-$41,706
07/2015-06/2017 Role of ventricular vagal dysfunction in ventricular arrhythmogenesis in heart failure. Grant-in-Aid from American Heart Association, 15GRANT24970002 (Principal Investigator: Yu-Long Li). Total funding-$143,000.
01/2016-12/2016 Informatics Education. Site PI- Jim McClay. Total Funding-$10,000
2014-2016 Team Dynamics in Emergency Medicine. Vietnam Educations Foundation. Site PI- Wes Zeger, Co-I- Thang Nguyen, Mike Wadman. Total Funding- $47,214