Category: Published Research
(Nature) The purposes of our study are to map high-risk areas in Canada as well as quantifying the effects of vaccination intervention and socio-demographic factors on the transmission rates of infection, recovery, and death related to COVID-19. The data of this research included weekly number of COVID‑19 cases, recovered, and dead individuals from 2020 through […]
Oct 24, 2022
(The Lancet) Estimates of immunity and severity for the SARS-CoV-2 omicron subvariant BA.5 are important to assess the public health impact associated with its rapid global spread despite vaccination. We estimated natural and vaccine immunity and severity of BA.5 relative to BA.2 in Denmark, a country with high mRNA-vaccination coverage and free-of-charge RT-PCR testing.
Oct 18, 2022
Monkeypox after Occupational Needlestick Injury from Pustule
CDC EID – We report a case of monkeypox in a physician after an occupational needlestick injury from a pustule. This case highlights risk for occupational transmission and manifestations of the disease after percutaneous transmission: a short incubation period, followed by a solitary lesion at the injured site and later by systemic symptoms.
Oct 18, 2022
Outcomes among confirmed cases and a matched comparison group in the Long-COVID in Scotland study
Nature – With increasing numbers infected by SARS-CoV-2, understanding long-COVID is essential to inform health and social care support. A Scottish population cohort of 33,281 laboratory-confirmed SARS-CoV-2 infections and 62,957 never-infected individuals were followed-up via 6, 12 and 18-month questionnaires and linkage to hospitalization and death records. Of the 31,486 symptomatic infections,1,856 (6%) had not […]
Oct 13, 2022
SARS-CoV-2 variants of concern and
variants under investigation in England
UK Health Security Agency – This report has been published to share the detailed variant surveillance analyses whichcontribute to the variant risk assessments and designation of new SARS-CoV-2 variants.This specialist technical briefing contains early data and analysis on emerging variants andfindings have a high level of uncertainty. Unless stated otherwise, this technical briefing uses a […]
Oct 13, 2022
Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults
JAMA – In this systematic review and meta-analysis of 38 studies comprising 2160 participants, exercise capacity was reduced by 4.9 mL/kg/min among individuals with symptoms consistent with LC compared with individuals without symptoms more than 3 months after SARS-CoV-2 infection. Findings among individuals with exertional intolerance suggest that deconditioning, dysfunctional breathing, chronotropic incompetence, and abnormal […]
Oct 13, 2022
JAMA – This observational analysis involved bayesian meta-regression and pooling of 54 studies and 2 medical record databases with data for 1.2 million individuals (from 22 countries) who had symptomatic SARS-CoV-2 infection. The modeled estimated proportion with at least 1 of the 3 self-reported Long COVID symptom clusters 3 months after symptomatic SARS-CoV-2 infection was […]
Oct 11, 2022
PLoS – Five-factor model personality traits (neuroticism, extraversion, openness, agreeableness, conscientiousness) are thought to be relatively impervious to environmental demands in adulthood. The coronavirus pandemic is an unprecedented opportunity to examine whether personality changed during a stressful global event. Surprisingly, two previous studies found that neuroticism decreased early in the pandemic, whereas there was less […]
Oct 5, 2022
Characteristics of long COVID among older adults: a cross-sectional study
International Journal of Infectious Diseases – 2333 individuals were evaluated at an average of 5 months [146 days (95% CI 142-150)] following COVID-19 onset. Mean age was 51 and 20.5% were>65 years. Older adults were more likely to be symptomatic, with most common symptoms being fatigue (38%) and dyspnea (30%). They were more likely to […]
Oct 4, 2022
Nature – The Omicron variant has been associated with reduced vaccine effectiveness (VE) against mild disease with rapid waning. Meanwhile Omicron has also been associated with milder disease. Protection against severe disease has been substantially higher than protection against infection with previous variants. We used a test-negative case-control design to estimate VE against hospitalisation with […]
Sep 30, 2022