University of Nebraska Medical Center
University of Nebraska Medical Center

Urinary Tract Infection Metric Frequently Asked Questions

Who receives a peer comparison?

Any clinician that prescribed 10 or more antibiotics for UTI within the targeted six-month period. Clinicians without at least 10 qualifying visits will not receive a peer comparison, but performance can be requested by emailing Mackenzie.keintz@unmc.edu.

What visits are included?

Visits are identified using ICD-10 codes for acute uncomplicated cystitis (N30.00, N30.01, N30.80, N30.81, N30.90, N30.91, N34.1, N34.2, N34.3, N39.0, N39.9), complicated UTI (N10), and asymptomatic UTI (R82.71).

What visits are not included?

We excluded patients with ICD-10 codes for renal transplant, neutropenia, nephrolithiasis, immunosuppression, urinary catheter use, or any additional code requiring antibiotics at time of visit. For a full list see below. Additionally, we excluded antibiotic prescriptions for >28 days duration (to avoid prophylactic antibiotic use) and patients with an exclusionary urologic procedure.

Excluded Patient Codes

Exclusion ICD-10 codes

Exclusion ICD-10 codes

Pregnancy

 

 

Z34.90, Z3A.01, Z3A.08-Z3A.42, Z3A.49, O48.1, O98.911-O98.919, Z33.1, Z32.01, O23.40, B95.5, O23.41, O99.891

Renal Transplant

 

T86.10, Z94.0

Neutropenia 

D70.9, D70.1-D70.4, Z91.89

Nephrolithiasis

N20.0

Immunosuppression

 

D84.9, D84.821

Urinary Catheter Use

  

 

T83.9XXA, Z96.00000, T83.518A,S, D, Z46.6, T83.511A,S,D, T83.098A,S,D, Z91.89

Additional code requiring antibiotics

H05.01*, H60.0*, H60.1*, H60.2*, H60.3*, H60.6*, H60.8*, H60.9*, H62.4*, H66.00*, H66.01*, H66.9*, H67.*, H70.00*, H70.01*, H70.09*, H70.9*, H79.89*, J01.*, J02.*, J03.*, J04.3*, J05.*, J15.*, J18.* except J18.2, K57.0*, K57.2*, K57.4*, K57.8*, K61.*, K65.* except K65.3 & K65.4, L01.* except L01.02 & L01.03, L02.*, L03.01*, L03.03*, L03.11*, L03.31*, L03.81*

Excluded Patient Codes

What antibiotics were evaluated?

Antibiotics associated with the included visit with UTI code (per inclusion/exclusion above) were evaluated.

What is considered an appropriate prescription?

To be considered an appropriate prescription the agent prescribed must be for either a first- or second-line UTI agent as well as have an appropriate daily dose (calculated from dose and frequency) and duration as defined below. Further information on antibiotic choice, duration, and dose can be found in our ambulatory UTI guidelines and the table below.

Where can I review the cases that were included?

You can request the list of included cases by emailing Dr. Mackenzie Keintz, ambulatory stewardship lead, at Mackenzie.keintz@unmc.edu.

Who has access to my performance data?

The ambulatory antibiotic stewardship team and your clinic medical director have access to your data. All provider performance data including those with <10 UTI prescriptions is provided to clinical medical directors.

Why is this data being provided to me and what should I do with it? 

This data is being provided as part of an ambulatory antibiotic stewardship initiative to improve patient outcomes and antibiotic use within Nebraska Medicine’s primary and immediate care clinics. We hope this helps clinicians identify opportunities for improvement in UTI antibiotic prescribing. Some clinicians will be invited to meet with antimicrobial stewardship experts for an in-deption review their personal data for. If you would like to meet for one of these sessions, please email Mackenzie.keintz@unmc.edu.

Should I try to get to 100% compliant?

The goal for appropriate prescribing is 90% to allow for some patients requiring an antibiotic that differs from general guidance (i.e. previous resistance patterns, antibiotic allergies, renal function abnormalities).

Antibiotic Recommendations for Urinary Tract Infections

Antimicrobial

Dosea

Frequencya

Duration

Cystitis - First-line antibiotics

Dosea

Frequencya

Duration

Nitrofurantoin

100mg

2 times daily

5 days

Trimethoprim-sulfamethoxazole

160/800mg

2 times daily

3 days

Fosfomycin

3g

Once

-

Cystitis - Second-line antibiotics

Dosea

Frequencya

Duration

Cephalexin

500-1000mg

2-3 times daily

5-7 days

Amoxicillin

500-1000mg

2-3 times daily

5-7 days

Amoxicillin/clavulanate

875/125mg

2 times daily

5-7 days

Cefadroxil

500-1000mg

2 times daily

5-7 days

Cefuroxime

250mg

2 times daily

5-7 days

Cefdinir

300mg

2 times daily

5-7 days

Cefpodoxime

100mg

2 times daily

5-7 days

Cystitis - Not routinely recommended

Dosea

Frequencya

Duration

Fluoroquinolone (levo-, moxi-, or ciprofloxacin)

-

-

-

Doxycycline

-

-

-

Minocycline

-

-

-

Omadacycline

-

-

-

Azithromycin

-

-

-

Clindamycin

-

-

-

Metronidazole

-

-

-

Complicated UTI - First line antibiotic

Dosea

Frequencya

Duration

Levofloxacin 

750mg

daily

5-7 days

Ciprofloxacin

500mg

2 times daily

5-7 days

Trimethoprim/sulfamethoxazole 

160/800mg

2 times daily

7--14 days

Complicated UTI - Second line antibiotics

Dosea

Frequencya

Duration

Amoxicillin-clavulanate

875/125mg

2 times daily

7-10 days

Cephalexin

500-1000mg

2-3 times daily

7-10 days

Cefuroxime

500-1000mg

2-3 times daily

7-10 days

Cefdinir

300mg

2 times daily

7-10 days

Cefpodoxime-proxetil 

100mg

2 times daily

7-10 days

Amoxicillin 

500-1000mg

2-3 times daily

7-10 days

Complicated UTI - Not routinely recommended

Dosea

Frequencya

Duration

Moxifloxacin 

-

-

-

Doxycycline 

-

-

-

Minocycline 

-

-

-

Omadacycline 

-

-

-

Azithromycin 

-

-

-

Clindamycin 

-

-

-

Metronidazole 

-

-

-

Antibiotic Recommendations for Urinary Tract Infections