Paul D. Fey, Ph.D.

Department Affiliations
Professor
Vice Chair, Research
Medical Director, Nebraska Medical Center Microbiology Section

Interests
Staphylococcal biology and pathogenesis, antibiotic resistance of clinical relevant pathogens
For more details on Dr. Fey's research, please visit his webpage.

Education and Training
B.S., Kansas State University, 1990 (Biology and Microbiology)
Ph.D., Creighton University, 1995 (Medical Microbiology)
Post-Doctoral Fellowship, Medical College of Virginia, 1995-1997
Diplomat American Board of Medical Microbiology D(ABMM), 2012 

Teaching Activities
Course coordinator/director: 

PAMM950 Bacterial Pathogenesis 

PAMM 871 Antibiotics-Mechanism of Action and Resistance 


Faculty advisor:
Tra-My N. Hoang, PhD candidate
Paroma Roy, PhD student
Chunyi Zhou, PhD Student

Medical school:
Defenders and Invaders Core leader
Medical Students - Streptococcal infections 

Direct clinical microbiology rounds for Infectious Disease/Pathology residents and fellows

National Activities
Member: American Society for Microbiology
Editor:  mSphere
Editorial Board: Antimicrobial Agents and Chemotherapy
March 2017: Center for Scientific Review Special Emphasis Panel.  Antimicrobial Resistance Rapid, Point of Need Diagnostic Test Challenge.  ZRG1 IDM-V (50); 
December 2016: Congressionally Directed Medical Research Programs; Infectious Disease (ID-2) study section; 
October 2016: NIH/NIAID ZRG1 IDM-B (80) S Topics in Bacterial Pathogenesis Study Section.  
March 2016: NIH/NIAID ZRG1 IDM-B (80) S Topics in Bacterial Pathogenesis Study Section. 
Editorial Board: Antimicrobial Agents and Chemotherapy


Publications (the last 2 years)

M. R. Galac, J. Stam, R. Maybank, M. Hinkle, D. Mack, H. Rohde, A. L. Roth, and P. D. Fey.  2017.  Complete genome sequence of Staphylococcus epidermidis 1457.  Genome Announce. 5(22) 

C.T. Marolf, R. Alter, E. Lyden, P.D. Fey, M.E. Rupp.  2017.  Susceptibility of Nosocomial Staphylococcus aureus to chlorhexidine after implementation of a hospital-wide antiseptic bathing regimen.  Infect Control Hosp Epidemiol. 5:1-3.   doi: 10.1017/ice.2017.80.

V.C. Thomas and P.D. Fey.  2017.  Biofilms:  Take my breath away.  eLife; 6:324739

Cawcutt, K., P.D. Fey, and A.C. Kalil.  2017.  Respiratory Pathogen Panels in the Hospital:  Good or Unnecessary? Curr Opin Infect Dis. 30:226-230

Cortney R. Halsey, Shulei Lei, Jacqueline Wax, McKenzie K. Lehman, Austin S. Nuxoll, Laurey Steinke, Marat Sadykov, Robert Powers, and Paul D Fey. 2017. Amino acid catabolism in Staphylococcus aureus and the function of carbon catabolite repression. mBio 2017 Feb 14;8(1).

Alexandra E. Paharik, Marta Kotasinska, Henning Büttner, Anna Both, Tra-My Hoang, Paroma Roy, Paul D. Fey, Alexander R. Horswill, and Holger Rohde.  2017.  The metalloprotease SepA governs processing of accumulation-associated protein and shapes intercellular adhesive surface properties in Staphylococcus epidermidis.  Mol Microbiol 103(5):860-874

C. N Murphy, R. C. Fowler, P. C. Iwen, and P. D. Fey.  2016.  Evaluation of the BioFire FilmArray® Gastrointestinal Panel in a Midwestern Academic Hospital.  Eur J Clin Microbiol Infect Dis. Epub ahead of print

C. R. Schaeffer, Tra-My N. Hoang, C. M. Sudbeck, M. Alawi, I. E. Tolo, D. A. Robinson, A. R. Horswill, H. Rohde, and P.D. Fey.  2016.  Versatility of biofilm matrix molecules in Staphylococcus epidermidis clinical isolates and importance of polysaccharide intercellular adhesin (PIA) expression during high shear stress.  mSphere Oct 5;1(5). pii: e00165-16 PMID: 27747298

Andre C. Kalil, Mark L. Metersky, Michael Klompas, John Muscedere, Daniel A. Sweeney, Lucy B. Palmer, Lena M. Napolitano, Naomi P. O'Grady, John G.Bartlett, Jordi Carratal, Ali A. El Solh, Santiago Ewig, Paul D. Fey, Thomas M. File, Jr., Marcos I. Restrepo, Jason A. Roberts, Grant W. Waterer, Peggy Cruise, MLIS, Shandra Protzko, MLIS, and Jan L. Brozek. 2016. Executive Summary: Management of Adults with Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society. Clin Infect Dis 63(5):575-828 doi: 10.1093/cid/ciw504.

Sarah Rowe, Christopher Campbell, Colm Lowry, Sinead O'Donnell, Michael Olson, Jill Lindgren, Elaine Waters, Paul D Fey, and James O'Gara.  2016 AraC-type regulator Rbf controls the Staphylococcus epidermidis biofilm phenotype by negatively regulating the icaADBC repressor SarR.   J. Bacteriol. 198:2914-2924.  PMID: 27521441

Andre C. Kalil, Mark L. Metersky, Michael Klompas, John Muscedere, Daniel A. Sweeney, Lucy B. Palmer, Lena M. Napolitano, Naomi P. O'Grady, John G. Bartlett, Jordi Carratalà, Ali A. El Solh, Santiago Ewig, Paul D. Fey, Thomas M. File, Jr. Marcos I. Restrepo, Jason A. Roberts, Grant W. Waterer, Peggy Cruise, MLIS, Shandra Protzko, MLIS, and Jan L. Brozek.  2016.  Management of Adults with Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society.  Clin Infect Dis. 63(5):e61-e111 doi: 10.1093/cid/ciw353

 International Typhoid Consortium, Wong VK, Holt KE, Okoro C, Baker S, Pickard DJ, Marks F, Page AJ, Olanipekun G, Munir H, Alter R, Fey PD, Feasey NA, Weill FX, Le Hello S, Hart PJ, Kariuki S, Breiman RF, Gordon MA, Heyderman RS, Jacobs J, Lunguya O, Msefula C, MacLennan CA, Keddy KH, Smith AM, Onsare RS, De Pinna E, Nair S, Amos B, Dougan G, Obaro S. 2016. Molecular Surveillance Identifies Multiple Transmissions of Typhoid in West Africa.  PLoS Negl Trop Dis Sep 22;10(9):e0004781. doi: 10.1371/journal.pntd.0004781.

 H. McCarthy, E. Waters, J. Bose, S. Foster, K. Bayles, E. O'Neill, P.D. Fey, J. P. O'Gara.  2016.  The major autolysin is redundant for Staphylococcus aureus USA300 LAC JE2 virulence in a murine device-related infection model.  FEMS Microbiol Lett 363(9). pii: fnw087. doi: 10.1093/femsle/fnw087.

 V.K. Yajjala, V.C. Thomas, C. Bauer, T.D. Scherr, P.D. Fey, K.W. Bayles, T. Kielian, and K. Sun.  2016.  Resistance to Macrophage killing promotes airway fitness of prevalent community-acquired S. aureus strains.  J Immunol 15;196(10):4196-203. doi: 10.4049/jimmunol.1600081.

For a detailed list of publications, click here.