Paul D. Fey, PhD

Department Affiliations
Vice Chair, Research
Medical Director, Nebraska Medical Center Microbiology Section

Staphylococcal biology and pathogenesis, antibiotic resistance of clinical relevant pathogens
For more details on Dr. Fey's research, please visit his webpage.

Education and Training
BS, Kansas State University, 1990 (Biology and Microbiology)
PhD, Creighton University, 1995 (Medical Microbiology)
Post-Doctoral Fellowship, Medical College of Virginia, 1995-1997
Diplomat American Board of Medical Microbiology D(ABMM), 2012 

Teaching Activities
Course coordinator/director: 
PAMM910 Bacterial Pathogenesis 
PAMM 871 Antibiotics-Mechanism of Action and Resistance 

Medical school:
Defenders and Invaders Core leader
Medical Students - Streptococcal infections 
Direct clinical microbiology rounds for Infectious Disease/Pathology residents and fellows

National Activities
Member: American Society for Microbiology
Editor:  mSphere
Editorial Board: Antimicrobial Agents and Chemotherapy
March 2017: Center for Scientific Review Special Emphasis Panel.  Antimicrobial Resistance Rapid, Point of Need Diagnostic Test Challenge.  ZRG1 IDM-V (50); 
December 2016: Congressionally Directed Medical Research Programs; Infectious Disease (ID-2) study section; 
October 2016: NIH/NIAID ZRG1 IDM-B (80) S Topics in Bacterial Pathogenesis Study Section.  
March 2016: NIH/NIAID ZRG1 IDM-B (80) S Topics in Bacterial Pathogenesis Study Section. 
Editorial Board: Antimicrobial Agents and Chemotherapy

Publications (the last 2 years)

Bralita, D.M., Cushman-Vokoun, A.M., Wood, M.G., Crowley, A.M., Rapp, S.A., Fey, P.D., Rupp, M.E., Hewlett, A.L.  2022.  Prolonged SARS-CoV-2 Viral shedding in lower respiratory specimens of critically ill patients does not correlate with nasoparyngeal swab results.  Infect. Control Hosp. Epidemiol.  May 24:1-6.  Doi: 10.1017/ice.2022.139. PMID: 35607806 

Reslane, I., C. Halsey, A. Stastny, B.J. Cabrera, J.S. Ahn, D. Shinde, M.R. Galac, M. Sladek, F. Razvi, M.K. Lehman, K.W. Bayles, V.C. Thomas, L.D. Handke, and P.D. Fey.  2022.  Catabolic Ornithine Carbamoyl Transferase activity facilitates growth of Staphylococcus aureus in defined medium lacking glucose and arginine.  mBio. 2022 Apr 27:e0039522. doi: 10.1128/mbio.00395-22. PMID: 35475645  

Reslane, I., Sladek, M., Fey, P.D., and Abdalhamid, B.  2021.  Whole-Genome Sequences of Staphylococcus aureus isolates from positive blood cultures.  Microbiol Resour Announc. 2021 Oct 28;10(43):e0089821. doi: 10.1128/MRA.00898-21. Epub 2021 Oct 28. PMID: 34709047. 

P. Roy, A.R. Horswill, and Fey, P.D.  2021.  Glycan-dependent corneocyte adherence of Staphylococcus. epidermidis mediated by the surface protein Aap.  mBio.  Jul 13:e0290820. doi: 10.1128/mBio.02908-20. PMID: 34253065.

Commentary:  S. Rahmdel and F. Gotz.  2021.  The Multitasking Surface Protein of Staphylococcus epidermidis:  Accumulation-Associated Protein (Aap).  mBio.  September/October Volume 12 Issue 5 e01989-21  

C. Campbell, C. Fingleton, G.C. Clair, E. Bueno, M.S. Zeden, L.A. Gallagher, D. Shinde, J. Ahn, H.M. Olson, T.L. Filmore, F. Razvi, K.W. Bayles, P.D. Fey, V.C. Thomas, F. Cava, J.N. Adkins, and J. P. O’Gara.  2021.  Succinylome-controlled b-lactam antibiotic resistance in MRSA.  mBio.  Jun 29;12(3):e0053021.  doi: 10.1128/mBio.00530-21. Epub 2021 Jun 29. PMID: 34182779.   

Megan E. Bosch, Blake P. Bertrand, Cortney E. Heim, Abdulelah A. Alqarzaee, Sujata S. Chaudhari, Amy L. Aldrich, Paul D. Fey, Vinai C. Thomas, and Tammy Kielian.  2020.  Staphylococcus aureus ATP synthase promotes biofilm persistence by influencing innate immunity.  mBio. Sep 8;11(5):e01581-20. doi: 10.1128/mBio.01581-20. PMID: 32900803. 

Rearigh, L., A. Hewlett, P.D. Fey, J.M. Broadhurst, David M. Brett-Major, M.E. Rupp, T.C. Van Schooneveld.  2020.  Utility of Repeat Testing for COVID-19:  Lab Stewardship when the stakes are high.  Infect Control Hosp. Epidemiology.  PMID: 32741393. 

Creager, H.M., B. Cabrera, A. Schnaubelt, J.L. Cox, A. M. Cushman-Vokoun, S.M. Shakir, K.D. Tardif, M-Li Huang, K.R. Jerome, A.L. Greninger, D. Drobysheva, U. Spaulding, M. Rogatcheva, K.M. Bourzac, S.H. Hinrichs, M.J. Broadhurst, and P.D. Fey.  2020.  Clinical Evaluation of the BioFire® Respiratory Panel 2.1 and detection of SARS CoV-2.  J. Clin. Virology.  Aug;129:104538. doi: 10.1016/j.jcv.2020.104538. PMID: 32650276. 

Brett-Major, D.M., Schnaubelt, E.R., Creager, H.M., Lowe, A., Cieslak, T.J., Dahlke, J.M., Johnson, D.W., Fey, P.D., Hansen, K.F., Hewlett, A.L., Gordon, B.G., Kalil, A.S., Kortepeter, M.G., Kratochvil, C.J., Larson, L., Levy, D.A., Linder, J., Medcalf, S.J., Rupp, M.E., Schwedhelm, M.M., Sullivan, J., Vasa, A.M., Wadman, M.C., Lookadoo, R.E., Lowe, J.J., Lawler, J.V., and Broadhurst, M.J.  2020.  Advanced Preparation Makes Research in Emergencies and Isolation Care Possible:  The Case of Coronavirus Disease.  Am. J. Trop Med Hyg. 102:926-931. PMID: 32228780. 

Zhou, C and P.D. Fey.  2020.  The Acid Response Network of Staphylococcus aureus.  Current Opinion in Microbiol. 55:67-73. PMID: 32361405.  

M.S. Zeden, I. Kviatkovski, V.C. Thomas, P.D. Fey and A. Grundling.  2020.  Staphylococcus aureus can survive in the absence of c-di-AMP upon inactivation of the main glutamine transporter. Mol Microbiol 113(6):1085-1100. PMID: 31997474. 

Islam, M.M., V.C. Thomas, M. Van Beek, J-S. Ahm, A.A. Alqarzaee, C. Zhou, P.D. Fey, K.W. Bayles, and R. Saha.  2020.  An integrated and computational and experimental study to elucidate Staphylococcus aureus metabolism.  Nat. Systems Biol Appl. Jan 30;6(1):3. PMID: 32001720.

For a detailed list of publications, click here.