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University of Nebraska Medical Center

Research

Our faculty work on clinical trials related to inflammatory bowel diseases, eosinophilic esophagitis, gastroparesis, alcoholic and non-alcoholic hepatitis, NASH, and other gastrointestinal and hepatology illnesses.

The Alcohol Liver Study Unit is comprised of a large team of basic scientists conducting ongoing research investigating:

  • How alcohol consumption affects protein degradation in the liver and the brain.
  • Ethanol metabolism on cellular replication.
  • Ethanol as it relates to altered protein trafficking and the pathogenesis of alcoholic liver injury.
  • The role of iron as a secondary risk factor in liver diseases, including oxidative stress induced by agents such as alcohol or hepatitis C viral proteins is one of the primary underlying mechanisms of iron overload.

Understanding these processes may help researchers develop novel diagnostic markers and therapeutic strategies.

 

Donate to the IBD Research and Education Fund

Faculty Research

Derrick Eichele, MD

Derrick Eichele, MD

Clinical outcomes in inflammatory bowel disease, clinical investigations of experimental pharmacological therapies.

Dr. Eichele's Clinical Trials

Alexander Hewlett, DO

Alexander Hewlett, DO

Outcomes in Gastroparesis, Pharmacological studies in Eosinophilic esophagitis, Patient outcomes in Eosinophilic esophagitis.

Dr. Hewlett's Clinical Trials

Peter J. Mannon, MD, MPH

Peter J. Mannon, MD, MPH

Specimen and Tissue Banking for the Study of Inflammatory Bowel Diseases

Wuttiporn (Shane) Manatsathit, MD

Wuttiporn (Shane) Manatsathit, MD

Non-alcoholic fatty liver disease (NAFLD), Non-invasive liver fibrosis measurements, Clinical care of liver transplant candidates and post-transplant care.

Dr. Manasathit's Clinical Trials