University of Nebraska Medical Center

Laboratory of Kamalika Mukherjee, MSc, PhD

Research Goals

The goals of our research are to identify key proteins and RNAs present in the extracellular vesicles derived from natural sources and glial cells that have immunomodulatory role to affect the immunoinflammatory processes in degenerating brain. I am using proteomic and transcriptomics analysis of EVs to explore the anti-inflammatory potential of EVs and their cargo proteins and RNA to restrict the inflammatory processes in AD and PD mouse brain.

Techniques used in laboratory

  • Extracellular vesicles
  • Proteomics and Transcriptomics analyses of exosomes or extracellular vesicles
  • Extracellular vesicles drug delivery vehicles
  • Neurodegenerative disorders
  • RNA binding proteins
  • miRNA export and turnover
  • Pro-inflammatory immune response in metabolic and infectious diseases
  • Anti-inflammatory immune response in metabolic and infectious diseases
  • Cellular stress response in hepatic cells


Margaret R. Larson Professor of Internal Medicine and Infectious Diseases
Chair, Department of Pharmacology and Experimental Neuroscience


Laboratory of Howard E. Gendelman, MD

Howard E. Gendelman, MD